Detailed information NTG0054491

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: UC509_RS13615
• Genome accession: NC_019435
• Coordinates: 1720089..1720598 (-)
• Length: 169 a.a.
• NCBI ID: WP_228764033.1
• Uniprot ID: -
• Organism: Lactococcus cremoris subsp. cremoris UC509.9
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1719121..1720012	1720089..1720598	flank	77

Gene organization within MGE regions

Location: 1719121..1720598

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UC509_RS12660	-	1719121..1720012 (-)	892	Protein_1674	IS982-like element IS982B family transposase	-
UC509_RS13615	comEC	1720089..1720598 (-)	510	WP_228764033.1	MBL fold metallo-hydrolase	Machinery gene

Sequence

Protein

• Length: 169 a.a.
• Molecular weight: 18909.59 Da
• Isoelectric Point: 6.9787

>NTDB_id=54491 UC509_RS13615 WP_228764033.1 1720089..1720598(-) (comEC) [Lactococcus cremoris subsp. cremoris UC509.9]
MRASITAVDIGQGDSIFLQDKFNKENILIDTGGRLALPQKNWQKAQTQSNADKTLIPYLESMGVAHIDQLILTHTDADHV
GDFLSLADKIKIREIWVSPGELTNISFVEKLKKAKIPIHVSKVGDKIPIFDSFLQVLSNGYTKKGDNNDSIVTYGNFYHT
KFLFTDPNC

Nucleotide

• Length: 510 bp

>NTDB_id=54491 UC509_RS13615 WP_228764033.1 1720089..1720598(-) (comEC) [Lactococcus cremoris subsp. cremoris UC509.9]
ATGAGAGCAAGCATTACAGCAGTTGATATCGGACAAGGAGATAGTATTTTTCTACAAGATAAGTTTAATAAAGAAAACAT
TCTGATTGATACTGGGGGACGACTTGCTCTTCCTCAAAAAAATTGGCAAAAAGCGCAGACGCAATCAAATGCTGACAAAA
CGCTTATCCCTTATTTAGAATCCATGGGGGTGGCTCATATTGACCAACTTATTCTGACTCATACAGATGCTGACCATGTT
GGCGATTTCTTGTCCTTAGCTGATAAAATAAAAATAAGAGAAATCTGGGTCAGTCCGGGAGAATTAACCAACATTAGTTT
TGTGGAAAAATTAAAAAAAGCAAAAATTCCGATTCATGTTAGTAAAGTTGGGGATAAAATTCCGATTTTTGATAGTTTTC
TTCAAGTTTTATCAAATGGTTACACTAAAAAAGGGGATAATAATGATTCCATAGTGACTTATGGAAACTTTTACCATACA
AAATTTCTTTTTACAGACCCGAATTGCTAG

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (11-104)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	99.394	97.633	0.97
comEC/celB	Streptococcus mitis SK321	47.305	98.817	0.467
comEC/celB	Streptococcus pneumoniae TIGR4	45.509	98.817	0.45
comEC/celB	Streptococcus pneumoniae Rx1	44.91	98.817	0.444
comEC/celB	Streptococcus pneumoniae D39	44.91	98.817	0.444
comEC/celB	Streptococcus pneumoniae R6	44.91	98.817	0.444
comEC/celB	Streptococcus mitis NCTC 12261	44.311	98.817	0.438
comEC	Latilactobacillus sakei subsp. sakei 23K	38.037	96.45	0.367