Detailed information
Bioinformatically predicted
Overview
| Name | mecA | Type | Regulator |
| Locus tag | JZY07_RS09790 | Genome accession | NZ_CP071305 |
| Coordinates | 1974379..1975101 (-) | Length | 240 a.a. |
| NCBI ID | WP_002938171.1 | Uniprot ID | A0A116M1G6 |
| Organism | Streptococcus suis strain SC183 | ||
| Function | degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1972822..2027262 | 1974379..1975101 | within | 0 |
Gene organization within MGE regions
Location: 1972822..2027262
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JZY07_RS09785 (JZY07_09785) | - | 1973210..1974382 (-) | 1173 | WP_002938168.1 | MraY family glycosyltransferase | - |
| JZY07_RS09790 (JZY07_09790) | mecA | 1974379..1975101 (-) | 723 | WP_002938171.1 | adaptor protein MecA | Regulator |
| JZY07_RS09795 (JZY07_09795) | - | 1975229..1976064 (-) | 836 | Protein_1908 | undecaprenyl-diphosphate phosphatase | - |
| JZY07_RS09800 (JZY07_09800) | - | 1976190..1977755 (+) | 1566 | WP_024412047.1 | ABC transporter substrate-binding protein/permease | - |
| JZY07_RS09805 (JZY07_09805) | - | 1977748..1978491 (+) | 744 | WP_012775335.1 | amino acid ABC transporter ATP-binding protein | - |
| JZY07_RS09810 (JZY07_09810) | - | 1978613..1978822 (-) | 210 | WP_009910800.1 | hypothetical protein | - |
| JZY07_RS09815 (JZY07_09815) | - | 1978908..1979810 (-) | 903 | WP_002937414.1 | SPFH domain-containing protein | - |
| JZY07_RS09820 (JZY07_09820) | ilvA | 1979820..1981070 (-) | 1251 | WP_024412048.1 | threonine ammonia-lyase IlvA | - |
| JZY07_RS09825 (JZY07_09825) | ilvC | 1981354..1982376 (-) | 1023 | WP_002942259.1 | ketol-acid reductoisomerase | - |
| JZY07_RS09830 (JZY07_09830) | ilvN | 1982508..1982984 (-) | 477 | WP_002937420.1 | acetolactate synthase small subunit | - |
| JZY07_RS09835 (JZY07_09835) | - | 1982977..1984679 (-) | 1703 | Protein_1916 | acetolactate synthase large subunit | - |
| JZY07_RS09840 (JZY07_09840) | - | 1984903..1985955 (+) | 1053 | WP_024412050.1 | bifunctional glycosyltransferase family 2/GtrA family protein | - |
| JZY07_RS09845 (JZY07_09845) | - | 1985942..1986880 (+) | 939 | WP_024400179.1 | phosphodiester glycosidase family protein | - |
| JZY07_RS11675 | - | 1986855..1987271 (+) | 417 | WP_079268037.1 | hypothetical protein | - |
| JZY07_RS09850 (JZY07_09850) | ilvD | 1987432..1989147 (+) | 1716 | WP_024400180.1 | dihydroxy-acid dehydratase | - |
| JZY07_RS09855 (JZY07_09855) | - | 1989202..1989597 (+) | 396 | WP_024400181.1 | DUF6176 family protein | - |
| JZY07_RS09860 (JZY07_09860) | - | 1989616..1989957 (-) | 342 | WP_009910815.1 | metal-sulfur cluster assembly factor | - |
| JZY07_RS11680 | - | 1990079..1990159 (-) | 81 | Protein_1923 | pyridoxamine 5'-phosphate oxidase family protein | - |
| JZY07_RS09865 (JZY07_09865) | - | 1990464..1993013 (-) | 2550 | WP_024400182.1 | SEC10/PgrA surface exclusion domain-containing protein | - |
| JZY07_RS09870 (JZY07_09870) | - | 1993144..1993485 (+) | 342 | WP_014638640.1 | helix-turn-helix transcriptional regulator | - |
| JZY07_RS09875 (JZY07_09875) | - | 1993960..1994517 (-) | 558 | WP_024412051.1 | hypothetical protein | - |
| JZY07_RS09880 (JZY07_09880) | - | 1994542..1996371 (-) | 1830 | WP_024412052.1 | XRE family transcriptional regulator | - |
| JZY07_RS09885 (JZY07_09885) | - | 1996380..1998605 (-) | 2226 | WP_024412053.1 | DEAD/DEAH box helicase family protein | - |
| JZY07_RS09890 (JZY07_09890) | - | 1998602..2000221 (-) | 1620 | WP_024412054.1 | site-specific DNA-methyltransferase | - |
| JZY07_RS09895 (JZY07_09895) | - | 2000807..2001292 (+) | 486 | WP_024412055.1 | helix-turn-helix transcriptional regulator | - |
| JZY07_RS09900 (JZY07_09900) | - | 2001436..2001756 (+) | 321 | WP_024401962.1 | hypothetical protein | - |
| JZY07_RS09905 (JZY07_09905) | - | 2001756..2002840 (+) | 1085 | Protein_1932 | AAA family ATPase | - |
| JZY07_RS09910 (JZY07_09910) | - | 2002840..2003451 (+) | 612 | WP_024412057.1 | hypothetical protein | - |
| JZY07_RS09915 (JZY07_09915) | - | 2003587..2004213 (+) | 627 | WP_024412058.1 | replication protein | - |
| JZY07_RS11685 | - | 2004176..2004364 (+) | 189 | WP_024412059.1 | helix-turn-helix domain-containing protein | - |
| JZY07_RS09920 (JZY07_09920) | - | 2004457..2005506 (+) | 1050 | WP_024412060.1 | site-specific integrase | - |
| JZY07_RS09925 (JZY07_09925) | rpsI | 2005563..2005955 (-) | 393 | WP_002942223.1 | 30S ribosomal protein S9 | - |
| JZY07_RS09930 (JZY07_09930) | rplM | 2005975..2006421 (-) | 447 | WP_024394920.1 | 50S ribosomal protein L13 | - |
| JZY07_RS09935 (JZY07_09935) | - | 2006886..2007749 (-) | 864 | WP_024400190.1 | DegV family protein | - |
| JZY07_RS09940 (JZY07_09940) | - | 2007746..2008267 (-) | 522 | WP_024400191.1 | NYN domain-containing protein | - |
| JZY07_RS09945 (JZY07_09945) | rlmB | 2008268..2008996 (-) | 729 | WP_002939457.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| JZY07_RS09950 (JZY07_09950) | - | 2009134..2009523 (+) | 390 | WP_024400192.1 | DUF1761 domain-containing protein | - |
| JZY07_RS09955 (JZY07_09955) | - | 2009598..2010566 (+) | 969 | WP_024400193.1 | aromatic acid exporter family protein | - |
| JZY07_RS09960 (JZY07_09960) | ugpC | 2010606..2011736 (-) | 1131 | WP_002938838.1 | sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC | - |
| JZY07_RS09965 (JZY07_09965) | - | 2011846..2012700 (-) | 855 | WP_024400194.1 | helix-turn-helix domain-containing protein | - |
| JZY07_RS09970 (JZY07_09970) | - | 2012702..2013100 (-) | 399 | WP_024400195.1 | Mini-ribonuclease 3 | - |
| JZY07_RS09975 (JZY07_09975) | cysS | 2013093..2014436 (-) | 1344 | WP_024400196.1 | cysteine--tRNA ligase | - |
| JZY07_RS09980 (JZY07_09980) | - | 2014626..2015399 (-) | 774 | WP_024400198.1 | nucleoside phosphorylase | - |
| JZY07_RS09985 (JZY07_09985) | cysE | 2015414..2016031 (-) | 618 | WP_024400199.1 | serine O-acetyltransferase | - |
| JZY07_RS09990 (JZY07_09990) | pnp | 2016084..2018303 (-) | 2220 | WP_024400200.1 | polyribonucleotide nucleotidyltransferase | - |
| JZY07_RS09995 (JZY07_09995) | - | 2018505..2019032 (+) | 528 | WP_024400201.1 | GNAT family N-acetyltransferase | - |
| JZY07_RS10000 (JZY07_10000) | - | 2019114..2020145 (-) | 1032 | WP_024400202.1 | MupG family TIM beta-alpha barrel fold protein | - |
| JZY07_RS10005 (JZY07_10005) | - | 2020135..2021562 (-) | 1428 | WP_024400203.1 | PTS transporter subunit EIIC | - |
| JZY07_RS10010 (JZY07_10010) | murQ | 2021564..2022475 (-) | 912 | WP_024400204.1 | N-acetylmuramic acid 6-phosphate etherase | - |
| JZY07_RS10015 (JZY07_10015) | - | 2022602..2023429 (+) | 828 | WP_024400205.1 | MurR/RpiR family transcriptional regulator | - |
| JZY07_RS10020 (JZY07_10020) | rpsO | 2023580..2023849 (-) | 270 | WP_024412061.1 | 30S ribosomal protein S15 | - |
| JZY07_RS10025 (JZY07_10025) | - | 2024053..2025330 (-) | 1278 | WP_014736408.1 | solute carrier family 23 protein | - |
| JZY07_RS10030 (JZY07_10030) | - | 2025549..2026022 (-) | 474 | WP_024395336.1 | DUF6773 family protein | - |
| JZY07_RS10035 (JZY07_10035) | - | 2026003..2026221 (-) | 219 | WP_014638668.1 | helix-turn-helix transcriptional regulator | - |
| JZY07_RS10040 (JZY07_10040) | - | 2026368..2026877 (-) | 510 | WP_024381091.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 240 a.a. Molecular weight: 27973.51 Da Isoelectric Point: 4.0497
>NTDB_id=544877 JZY07_RS09790 WP_002938171.1 1974379..1975101(-) (mecA) [Streptococcus suis strain SC183]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV
Nucleotide
Download Length: 723 bp
>NTDB_id=544877 JZY07_RS09790 WP_002938171.1 1974379..1975101(-) (mecA) [Streptococcus suis strain SC183]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTTTACACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATATTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGGGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACAGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATTGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTTTACACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATATTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGGGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACAGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATTGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| mecA | Streptococcus pneumoniae Rx1 |
51.639 |
100 |
0.525 |
| mecA | Streptococcus pneumoniae D39 |
51.639 |
100 |
0.525 |
| mecA | Streptococcus pneumoniae R6 |
51.639 |
100 |
0.525 |
| mecA | Streptococcus pneumoniae TIGR4 |
51.639 |
100 |
0.525 |
| mecA | Streptococcus mutans UA159 |
50 |
100 |
0.508 |
| mecA | Streptococcus thermophilus LMD-9 |
47.5 |
100 |
0.475 |
| mecA | Streptococcus thermophilus LMG 18311 |
47.083 |
100 |
0.471 |