Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   J0J35_RS00290 Genome accession   NZ_CP071301
Coordinates   50229..50924 (+) Length   231 a.a.
NCBI ID   WP_019292077.1    Uniprot ID   A0A139ME49
Organism   Lactococcus sp. LG606     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 45229..55924
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J0J35_RS00265 (J0J35_00265) - 45462..46163 (+) 702 WP_206917019.1 DeoR/GlpR family DNA-binding transcription regulator -
  J0J35_RS00270 (J0J35_00270) pfkB 46160..47086 (+) 927 WP_206917021.1 1-phosphofructokinase -
  J0J35_RS00275 (J0J35_00275) - 47101..49005 (+) 1905 WP_019293248.1 fructose-specific PTS transporter subunit EIIC -
  J0J35_RS00280 (J0J35_00280) - 49117..49359 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  J0J35_RS00285 (J0J35_00285) - 49576..50127 (+) 552 WP_206917023.1 DUF177 domain-containing protein -
  J0J35_RS00290 (J0J35_00290) covR 50229..50924 (+) 696 WP_019292077.1 response regulator transcription factor Regulator
  J0J35_RS00295 (J0J35_00295) covS 51012..52502 (+) 1491 WP_019293246.1 HAMP domain-containing histidine kinase Regulator
  J0J35_RS00300 (J0J35_00300) - 52892..54463 (+) 1572 WP_019293245.1 ABC transporter permease subunit -
  J0J35_RS00305 (J0J35_00305) - 54464..55201 (+) 738 WP_019292074.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 27037.77 Da        Isoelectric Point: 5.2713

>NTDB_id=544787 J0J35_RS00290 WP_019292077.1 50229..50924(+) (covR) [Lactococcus sp. LG606]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQDNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTIEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=544787 J0J35_RS00290 WP_019292077.1 50229..50924(+) (covR) [Lactococcus sp. LG606]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGATATCAAACTGCGGTTCAAGACAATGGTCGTAAAGGTCTTGAAGAAGCAATGTCAAAAGATTATGATTTGATTTTGC
TCGACTTAATGCTCCCAGAGCTGGATGGCTTTGAAGTTGCACGACGCTTACGCCGTGAAAAAGATACACATATTATTATG
ATGACTGCACGTGATTCAACTATGGACCGTGTAGCAGGTCTTGATATTGGAGCGGATGACTATATTACAAAACCATTCGC
AATTGAAGAATTGTTAGCGCGTGTCCGTTCACTCTTCCGTCGTGAAGACCATATCCACACGATTGAAAAATCAGACAATA
CTTCATTCCGTGATTTGGTAATTGATAAAACAAACCGCACTGTACATCGCGGAAAAAAAGTTATTGACCTTACACGTCGT
GAATACGATTTGCTTTTGACCCTGATGCAAAATGTGGGTGATGTCGTAACACGCGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTTGACGTTTATATCCGCTATTTGCGTAACAAAATTGACGTGGAAGGCCGCG
AAAGTTATATTCAAACGGTTCGTGGTATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(7-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139ME49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

88.21

99.134

0.874
  covR Streptococcus salivarius strain HSISS4

67.241

100

0.675
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424