Detailed information NTG0544788

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: J0J35_RS00295
• Genome accession: NZ_CP071301
• Coordinates: 51012..52502 (+)
• Length: 496 a.a.
• NCBI ID: WP_019293246.1
• Uniprot ID: A0AAJ2ML94
• Organism: Lactococcus sp. LG606
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 46012..57502

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J0J35_RS00270 (J0J35_00270)	pfkB	46160..47086 (+)	927	WP_206917021.1	1-phosphofructokinase	-
J0J35_RS00275 (J0J35_00275)	-	47101..49005 (+)	1905	WP_019293248.1	fructose-specific PTS transporter subunit EIIC	-
J0J35_RS00280 (J0J35_00280)	-	49117..49359 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
J0J35_RS00285 (J0J35_00285)	-	49576..50127 (+)	552	WP_206917023.1	DUF177 domain-containing protein	-
J0J35_RS00290 (J0J35_00290)	covR	50229..50924 (+)	696	WP_019292077.1	response regulator transcription factor	Regulator
J0J35_RS00295 (J0J35_00295)	covS	51012..52502 (+)	1491	WP_019293246.1	HAMP domain-containing histidine kinase	Regulator
J0J35_RS00300 (J0J35_00300)	-	52892..54463 (+)	1572	WP_019293245.1	ABC transporter permease subunit	-
J0J35_RS00305 (J0J35_00305)	-	54464..55201 (+)	738	WP_019292074.1	amino acid ABC transporter ATP-binding protein	-
J0J35_RS00310 (J0J35_00310)	murD	55341..56702 (+)	1362	WP_206917025.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56888.98 Da
• Isoelectric Point: 5.2995

>NTDB_id=544788 J0J35_RS00295 WP_019293246.1 51012..52502(+) (covS) [Lactococcus sp. LG606]
MVKFFDSKKKKAENLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESKLS
EDNLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSYGFPLRKDVGDSTHAVRTFGEYSGYLV
ERPVHSKKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLESIDFQDEDLICDPTEVSNFLKKNFLLIHPDLNLTVENYLTPGSLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
IVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=544788 J0J35_RS00295 WP_019293246.1 51012..52502(+) (covS) [Lactococcus sp. LG606]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAGCAGAAAATCTGCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
CTTTGCAAATACGATTTTTTGTTTTATAACCTTCACTATTTTTACAGTATTAGTTTATCAACTGACCATAACAACCTTCA
TCAATTCTGAAAAAGAGGACATGATGAAAGCTCTGGACAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCAAACTGTCG
GAGGACAATCTTGCGAATTATTTGGCTTATGCCAAAGACTACACAGCATCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGTTCTAGGAAGTCTTTTTATGTCTTTGATGTCGGTGAAAATTTGATTTATTCGACCAATTCGT
ATGGTTTCCCGCTAAGGAAAGATGTGGGGGATTCTACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTT
GAACGACCCGTTCATTCTAAGAAAACAGGGAAACTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTACAG
CGTGCGAACAAAGCTGCTGATTGCCCTGATTATCTTAGAAATTATTGCTCTCTTTATTGCTCAGTTTGTCGGTTATTTTA
TGGCAAGTCGCTATATCAAGCCTCTAGAGCGTTTGCACGATGCGATTACTACACGTGCCAATAATTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGCGATGAAATTGAAGAACTGGCGACTGTTTATAACGACATGATGATTAAGCTTAACGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGCTACGTACGCCACTTGCAGTTTTAGATGGTCATT
TGAATCTCTTGAATCGATGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTTAGC
ACGATGAGAACGATGTTAGAGGAGATGCTTGCATTGGCCCGTCTTGAAAGCATTGATTTTCAAGATGAAGATCTGATCTG
TGATCCAACAGAAGTTTCTAATTTTCTTAAGAAAAACTTTCTCCTTATTCATCCTGATTTAAATTTAACTGTTGAGAATT
ACTTGACGCCGGGTAGTTTGGCTCATATTTATCCCAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCGATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGACAAATACATTATTACAACAGTTGAGGA
TCGTGGCTATGGCATTAGTCAAGAAGATTTAAAACATGTCTTTGAGCGCTTTTTCCGTGCCGATAAAGCACGAAATCGAG
ATATAGGTGGAACAGGTCTTGGTCTGTCTATTATCCAACGCATAGTGGAAAACTATGACGGGGATGTCAGTGTGACTTCC
ATTGTAGGCGAAGGATCGAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• HAMP domain (HAMP) (214-266)

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• ArlS sensor domain (ArlS_N) (52-190)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.823	100	0.56