Detailed information NTG0054469

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: UC509_RS08620
• Genome accession: NC_019435
• Coordinates: 1720595..1721866 (-)
• Length: 423 a.a.
• NCBI ID: WP_324187032.1
• Uniprot ID: -
• Organism: Lactococcus cremoris subsp. cremoris UC509.9
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1719121..1720012	1720595..1721866	flank	583

Gene organization within MGE regions

Location: 1719121..1721866

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UC509_RS12660	-	1719121..1720012 (-)	892	Protein_1674	IS982-like element IS982B family transposase	-
UC509_RS13615	comEC	1720089..1720598 (-)	510	WP_228764033.1	MBL fold metallo-hydrolase	Machinery gene
UC509_RS08620 (uc509_1725)	comEC	1720595..1721866 (-)	1272	WP_324187032.1	ComEC/Rec2 family competence protein	Machinery gene

Sequence

Protein

• Length: 423 a.a.
• Molecular weight: 49044.21 Da
• Isoelectric Point: 9.7194

>NTDB_id=54469 UC509_RS08620 WP_324187032.1 1720595..1721866(-) (comEC) [Lactococcus cremoris subsp. cremoris UC509.9]
MIPILIVFAVFFLLINSLSIRDNENQPKNLSKIELIPDTIQVNGDLLSFQGRMNGQKYQVYDTLKSLKEKGFYQNLSQNC
QLSFTGNLEIPETQRNFNGFDDQKYLTSQNIYRQITIQQITNVEIKKNFDLHTLRRKAIVWTQNHFPKPMSDYMTGLLFG
FLSKDFNQMSDIYSSLGIIHLFALSGMQVNFFIDWFRKILLRMGLTRERVNLVQIPFSIFYAFMTGLSVSVLRALFQKNI
RLTSLDNIAVTTLVLMLISPKFLLTTGGQLTLFYAFVISMLNHPFSNLNGLKKVLTESSVLSLCVLPLLIFDFHIFQPLS
ILLTIIFGFLFDFMLLPLLLCCFLISFLGFLLNLNYIFQILEWLVYKVDLPLHYPFVLGKPSSLELIILFVLIGLFVDSF
SHKKRRFFLIGFIFLFFSSLKIQ

Nucleotide

• Length: 1272 bp

>NTDB_id=54469 UC509_RS08620 WP_324187032.1 1720595..1721866(-) (comEC) [Lactococcus cremoris subsp. cremoris UC509.9]
ATGATTCCGATATTAATTGTTTTTGCTGTATTTTTTCTGTTAATCAATAGTCTTAGTATTAGGGATAATGAAAATCAACC
AAAAAATCTCTCAAAAATTGAATTAATTCCAGATACAATCCAAGTCAATGGTGATTTATTGAGTTTTCAGGGGAGAATGA
ATGGACAAAAATATCAAGTCTATGACACATTGAAAAGTCTAAAAGAGAAAGGGTTTTATCAGAACTTAAGTCAAAATTGT
CAGTTAAGTTTCACAGGAAACCTTGAAATACCAGAAACTCAGCGAAATTTTAATGGTTTTGATGACCAAAAATATTTAAC
TAGTCAAAATATCTATCGACAGATTACCATCCAACAAATTACAAATGTGGAAATAAAAAAGAATTTTGACCTTCATACTT
TAAGGCGAAAGGCAATTGTTTGGACACAAAATCATTTTCCAAAACCGATGAGTGACTATATGACAGGTTTGCTTTTTGGC
TTTTTAAGTAAGGATTTTAATCAGATGAGCGATATTTATAGCTCTTTAGGAATTATTCATCTTTTTGCTCTATCAGGAAT
GCAAGTAAATTTTTTTATTGATTGGTTTCGTAAAATACTTCTTCGCATGGGACTGACGAGAGAAAGAGTGAATCTTGTTC
AAATTCCATTTTCTATTTTTTATGCTTTTATGACGGGATTATCGGTTTCAGTTTTAAGAGCCCTTTTTCAAAAAAATATT
CGTCTGACTTCTTTGGATAATATCGCAGTTACGACATTAGTTTTGATGCTCATAAGTCCAAAATTTTTACTGACGACTGG
TGGTCAGCTTACCTTGTTTTATGCTTTTGTCATTTCGATGCTTAATCATCCTTTTTCTAATTTAAATGGATTGAAAAAAG
TGCTGACAGAATCATCAGTCCTTTCACTTTGTGTTCTTCCGTTACTCATCTTTGATTTCCATATTTTTCAGCCTCTTTCA
ATATTATTAACAATTATATTTGGTTTTCTTTTTGATTTTATGTTGCTCCCGCTGCTTTTATGCTGTTTTCTTATATCATT
TTTGGGATTTTTGCTCAATTTAAATTATATTTTTCAAATTCTAGAATGGCTAGTTTATAAAGTTGATTTACCCTTACATT
ACCCCTTTGTTTTGGGGAAACCTAGTTCACTCGAATTAATTATTCTATTTGTGTTAATTGGTTTATTCGTAGATTCATTT
TCTCATAAAAAAAGGAGATTTTTTTTAATTGGATTTATATTTTTATTTTTTTCATCACTAAAAATCCAATGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (157-397)

• Domain of unknown function (DUF4131) (DUF4131) (56-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	96.882	98.582	0.955
comEC/celB	Streptococcus mitis SK321	46.512	91.489	0.426
comEC/celB	Streptococcus mitis NCTC 12261	45.995	91.489	0.421
comEC/celB	Streptococcus pneumoniae TIGR4	45.995	91.489	0.421
comEC/celB	Streptococcus pneumoniae Rx1	45.22	91.489	0.414
comEC/celB	Streptococcus pneumoniae D39	45.22	91.489	0.414
comEC/celB	Streptococcus pneumoniae R6	45.22	91.489	0.414