Detailed information NTG0544680

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: J0J36_RS07345
• Genome accession: NZ_CP071293
• Coordinates: 1485395..1487542 (+)
• Length: 715 a.a.
• NCBI ID: WP_153925280.1
• Uniprot ID: -
• Organism: Lactococcus sp. LG1074
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	1480541..1499239	1485395..1487542	within	0

Gene organization within MGE regions

Location: 1480541..1499239

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J0J36_RS07300 (J0J36_07300)	-	1480541..1481242 (-)	702	WP_153925534.1	AbiH family protein	-
J0J36_RS07305 (J0J36_07305)	-	1481211..1481588 (-)	378	WP_153925264.1	hypothetical protein	-
J0J36_RS10735	-	1482109..1482243 (+)	135	WP_368819573.1	putative holin-like toxin	-
J0J36_RS07310 (J0J36_07310)	-	1482453..1482878 (-)	426	WP_153925267.1	hypothetical protein	-
J0J36_RS07315 (J0J36_07315)	-	1482907..1483296 (-)	390	WP_333493046.1	DUF5677 domain-containing protein	-
J0J36_RS07320 (J0J36_07320)	-	1483341..1483466 (-)	126	WP_242520601.1	helix-turn-helix domain-containing protein	-
J0J36_RS07325 (J0J36_07325)	-	1483468..1484014 (-)	547	Protein_1454	recombinase family protein	-
J0J36_RS10690 (J0J36_07330)	-	1484423..1484608 (+)	186	WP_165719075.1	bacteriocin	-
J0J36_RS07335 (J0J36_07335)	-	1484654..1484953 (+)	300	WP_153925273.1	hypothetical protein	-
J0J36_RS07340 (J0J36_07340)	-	1485021..1485287 (+)	267	WP_153925277.1	bacteriocin immunity protein	-
J0J36_RS07345 (J0J36_07345)	comA	1485395..1487542 (+)	2148	WP_153925280.1	peptide cleavage/export ABC transporter	Regulator
J0J36_RS07350 (J0J36_07350)	-	1487552..1488979 (+)	1428	WP_153925283.1	bacteriocin secretion accessory protein	-
J0J36_RS07355 (J0J36_07355)	-	1489436..1489885 (-)	450	WP_242520602.1	hypothetical protein	-
J0J36_RS10680	-	1489959..1490150 (-)	192	WP_255566820.1	tyrosine-type recombinase/integrase	-
J0J36_RS07360 (J0J36_07360)	-	1490096..1490896 (-)	801	WP_255566821.1	tyrosine-type recombinase/integrase	-
J0J36_RS07365 (J0J36_07365)	eno	1490983..1492284 (-)	1302	WP_003133057.1	surface-displayed alpha-enolase	-
J0J36_RS07370 (J0J36_07370)	-	1492422..1492898 (-)	477	WP_017370512.1	GNAT family N-acetyltransferase	-
J0J36_RS07375 (J0J36_07375)	rplT	1492959..1493318 (-)	360	WP_003133061.1	50S ribosomal protein L20	-
J0J36_RS07380 (J0J36_07380)	rpmI	1493494..1493694 (-)	201	WP_003133063.1	50S ribosomal protein L35	-
J0J36_RS07385 (J0J36_07385)	infC	1493724..1494299 (-)	576	WP_080567137.1	translation initiation factor IF-3	-
J0J36_RS07390 (J0J36_07390)	-	1494755..1496074 (-)	1320	WP_206886702.1	ISLre2 family transposase	-
J0J36_RS07395 (J0J36_07395)	-	1496154..1497311 (+)	1158	Protein_1469	IS3 family transposase	-
J0J36_RS07400 (J0J36_07400)	-	1497297..1498250 (-)	954	WP_003134352.1	family 20 glycosylhydrolase	-
J0J36_RS07405 (J0J36_07405)	-	1498346..1499239 (-)	894	WP_003134350.1	SPFH domain-containing protein	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80734.32 Da
• Isoelectric Point: 8.5587

>NTDB_id=544680 J0J36_RS07345 WP_153925280.1 1485395..1487542(+) (comA) [Lactococcus sp. LG1074]
MRFKKKYYTSQIDERDCGCAALSMVLKAYGTEQSLASLRLLAGTTIEGTSALGIKKAAEHLKFSVQAFRADSTLFDTKKL
PCPFIIHVVKEKKYPHYYVVKYSNKKHIIIADPDPTVKIRKMTWDQFYSEWTGVTLFIAPQPSYKPVKEKSESLFSFIPL
IAKQKLLVCQIIIASLLVTLINIIGSYYLQNIIDEYVPNALMKTLGIVSLGLMATYFIQQILNFAQTFLLTILGQRLAID
VILSYIRHIFQLPMSFFSTRRTGEITSRFSDANSIIDALASAILSLFLDVTIVILTGLVLGLQNMSLFFLVLFSIPLYVL
IIFIFIPLFEKQNNEVMQANSILNSSIIEDINGIETIKSLGSEEIRYQKIDREFADYMKKSFTRQKSEAFQTALKSGLQL
VLNVLILWYGATLVVSQKITLGQLITFNVLLSYFMNPLSNIINLQTKLQSAKVANHRLNEVYLVDSEFDTKTDEIILSNF
EMQLIGISYHYGFGRDILSNISLNIKENEKLTIVGMSGSGKSTLVKLLVNFFEPTQGTIILGGIDIKQMDKHQLRRIVSY
LPQHPYIFTGTVLDNLTLGVSEDISQEEIFQAVEAAEIRSDIEQLQLGYQTELSSDATTLSGGQKQRIALARTLLSPAKI
LIFDEATSNLDVITEKKILKNLFKLDKTIIFIAHRLSIAEKSDRIVVIDQGKIMEEGSHLELLSKNGFYAQLYNQ

Nucleotide

• Length: 2148 bp

>NTDB_id=544680 J0J36_RS07345 WP_153925280.1 1485395..1487542(+) (comA) [Lactococcus sp. LG1074]
ATGCGTTTTAAAAAGAAATATTATACTTCACAAATAGATGAAAGAGATTGTGGGTGTGCTGCCCTTTCCATGGTTTTAAA
AGCTTATGGTACAGAACAATCTCTTGCTTCATTACGTTTACTTGCTGGTACAACGATAGAAGGTACCTCTGCTCTAGGTA
TTAAAAAAGCCGCAGAACATTTGAAATTCAGCGTTCAAGCCTTTCGTGCAGATTCAACTCTATTTGATACAAAAAAACTT
CCTTGTCCATTTATCATTCATGTGGTTAAAGAAAAGAAATATCCTCACTACTATGTGGTTAAATATTCCAATAAAAAACA
CATCATTATTGCAGACCCAGATCCCACGGTTAAAATTCGAAAAATGACGTGGGACCAATTTTATTCTGAATGGACAGGAG
TAACTTTATTTATTGCTCCTCAACCTTCTTATAAACCAGTGAAAGAAAAATCCGAGTCTTTGTTTTCTTTTATCCCCCTC
ATCGCAAAGCAAAAGCTGCTTGTTTGTCAGATTATTATTGCTTCTCTTTTAGTCACTTTAATTAATATTATTGGCTCTTA
TTATCTTCAGAATATTATTGACGAATATGTGCCTAATGCTTTAATGAAAACTTTAGGCATTGTTTCGCTTGGATTAATGG
CAACATATTTCATCCAGCAAATTCTTAATTTTGCTCAAACTTTCTTACTTACAATACTTGGACAACGTTTAGCCATTGAT
GTTATCCTTTCCTATATCCGTCATATTTTTCAACTTCCTATGTCTTTCTTTTCTACACGAAGAACGGGAGAAATTACCAG
TCGTTTCTCTGACGCCAATTCAATTATTGATGCCCTTGCTTCTGCCATCTTATCCCTTTTCTTAGATGTCACGATTGTCA
TTCTGACAGGGCTTGTTTTAGGACTTCAAAACATGAGCTTATTCTTCCTTGTCTTGTTTTCAATTCCGCTTTATGTTCTT
ATCATTTTTATTTTTATTCCTTTATTTGAAAAACAAAATAATGAAGTCATGCAAGCAAATTCTATTTTAAATTCTTCAAT
TATTGAGGATATCAATGGAATTGAAACCATAAAATCTCTTGGGAGTGAAGAGATTCGCTATCAAAAAATAGACCGTGAAT
TTGCGGACTACATGAAAAAATCATTCACGCGTCAAAAATCCGAAGCTTTTCAAACTGCCTTGAAATCAGGATTACAACTT
GTTTTAAATGTACTTATCTTGTGGTATGGAGCCACCCTCGTGGTGAGTCAAAAAATCACCTTGGGTCAATTAATTACTTT
CAATGTCTTACTTTCATACTTTATGAATCCTCTTTCTAATATCATCAACTTACAAACTAAACTTCAATCCGCTAAAGTAG
CTAATCATCGCTTAAATGAAGTTTACTTGGTAGACAGTGAATTTGATACAAAAACAGATGAAATTATTCTTTCAAATTTT
GAGATGCAGTTGATAGGTATATCTTACCACTATGGTTTTGGTAGAGACATTCTTTCTAATATTTCACTTAATATAAAAGA
AAATGAAAAATTAACAATTGTCGGAATGAGTGGCTCAGGTAAAAGTACCCTAGTCAAATTGTTGGTTAATTTTTTCGAAC
CTACACAAGGGACTATCATTCTTGGGGGGATAGATATAAAACAAATGGATAAACATCAACTCAGAAGGATTGTCAGCTAT
CTTCCCCAACACCCCTATATCTTCACTGGAACAGTACTTGATAATTTAACCTTAGGAGTAAGTGAGGATATTTCTCAGGA
AGAAATTTTCCAAGCTGTTGAAGCTGCGGAAATTCGTTCCGATATTGAACAACTTCAATTGGGCTATCAAACGGAGCTTT
CTAGTGATGCTACAACTCTCTCTGGAGGTCAAAAACAAAGAATCGCATTGGCTCGTACCTTACTTTCTCCCGCAAAGATC
CTTATTTTTGATGAAGCAACAAGTAATCTGGACGTAATTACCGAGAAAAAAATTTTGAAAAATCTATTTAAGTTAGATAA
AACCATTATTTTTATTGCCCATCGTCTGTCTATCGCGGAAAAGAGCGACAGGATTGTTGTTATTGATCAGGGAAAAATTA
TGGAAGAAGGTAGTCATTTAGAACTGCTTTCTAAAAATGGTTTTTATGCACAACTTTATAATCAATAG

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (6-142)

• ABC transporter (ABC_tran) (498-648)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	60.475	100	0.606
comA	Streptococcus mitis NCTC 12261	59.637	100	0.597
comA	Streptococcus mitis SK321	59.497	100	0.596
comA/nlmT	Streptococcus mutans UA159	59.275	100	0.594
comA	Streptococcus pneumoniae D39	59.218	100	0.593
comA	Streptococcus pneumoniae R6	59.218	100	0.593
comA	Streptococcus pneumoniae Rx1	59.218	100	0.593
comA	Streptococcus pneumoniae TIGR4	58.939	100	0.59