Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   J0J32_RS02150 Genome accession   NZ_CP071285
Coordinates   444957..445652 (+) Length   231 a.a.
NCBI ID   WP_004259096.1    Uniprot ID   -
Organism   Lactococcus garvieae strain LG728     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 439957..450652
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J0J32_RS02125 (J0J32_02125) - 440190..440891 (+) 702 WP_004259114.1 DeoR/GlpR family DNA-binding transcription regulator -
  J0J32_RS02130 (J0J32_02130) pfkB 440888..441814 (+) 927 WP_004259111.1 1-phosphofructokinase -
  J0J32_RS02135 (J0J32_02135) - 441829..443733 (+) 1905 WP_004259108.1 fructose-specific PTS transporter subunit EIIC -
  J0J32_RS02140 (J0J32_02140) - 443845..444087 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  J0J32_RS02145 (J0J32_02145) - 444304..444855 (+) 552 WP_004259099.1 YceD family protein -
  J0J32_RS02150 (J0J32_02150) covR 444957..445652 (+) 696 WP_004259096.1 response regulator transcription factor Regulator
  J0J32_RS02155 (J0J32_02155) covS 445741..447231 (+) 1491 WP_004259093.1 HAMP domain-containing histidine kinase Regulator
  J0J32_RS02160 (J0J32_02160) - 447628..449199 (+) 1572 WP_004259090.1 ABC transporter permease subunit -
  J0J32_RS02165 (J0J32_02165) - 449200..449937 (+) 738 WP_004259087.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 26979.74 Da        Isoelectric Point: 5.4730

>NTDB_id=544581 J0J32_RS02150 WP_004259096.1 444957..445652(+) (covR) [Lactococcus garvieae strain LG728]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQGNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTIEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=544581 J0J32_RS02150 WP_004259096.1 444957..445652(+) (covR) [Lactococcus garvieae strain LG728]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGATACCAAACTGCGGTTCAAGGCAATGGTCGTAAAGGTCTTGAAGAAGCAATGTCAAAAGATTATGATTTGATTTTGC
TTGACTTAATGCTCCCAGAGCTTGATGGCTTTGAGGTTGCACGACGCTTACGCCGTGAAAAAGATACACATATTATTATG
ATGACTGCACGTGATTCGACAATGGACCGTGTAGCAGGTCTTGATATTGGCGCAGATGACTATATTACAAAACCATTTGC
TATTGAAGAATTGTTAGCGCGTGTCCGCTCACTCTTCCGTCGTGAAGATCATATCCACACGATTGAAAAGTCAGACAATA
CTTCATTCCGTGATTTGGTAATTGATAAGACCAACCGTACTGTACACCGTGGAAAAAAAGTTATTGACCTTACACGCCGT
GAGTACGATTTGCTTTTGACATTGATGCAAAATGTAGGTGATGTCGTAACACGTGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTGGACGTTTATATCCGTTATCTGCGTAACAAAATTGACGTGGAGGGCCGTG
AAAGCTATATCCAAACGGTTCGTGGTATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(7-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

87.773

99.134

0.87
  covR Streptococcus salivarius strain HSISS4

66.81

100

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424