Detailed information NTG0544582

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: J0J32_RS02155
• Genome accession: NZ_CP071285
• Coordinates: 445741..447231 (+)
• Length: 496 a.a.
• NCBI ID: WP_004259093.1
• Uniprot ID: -
• Organism: Lactococcus garvieae strain LG728
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 440741..452231

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J0J32_RS02130 (J0J32_02130)	pfkB	440888..441814 (+)	927	WP_004259111.1	1-phosphofructokinase	-
J0J32_RS02135 (J0J32_02135)	-	441829..443733 (+)	1905	WP_004259108.1	fructose-specific PTS transporter subunit EIIC	-
J0J32_RS02140 (J0J32_02140)	-	443845..444087 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
J0J32_RS02145 (J0J32_02145)	-	444304..444855 (+)	552	WP_004259099.1	YceD family protein	-
J0J32_RS02150 (J0J32_02150)	covR	444957..445652 (+)	696	WP_004259096.1	response regulator transcription factor	Regulator
J0J32_RS02155 (J0J32_02155)	covS	445741..447231 (+)	1491	WP_004259093.1	HAMP domain-containing histidine kinase	Regulator
J0J32_RS02160 (J0J32_02160)	-	447628..449199 (+)	1572	WP_004259090.1	ABC transporter permease subunit	-
J0J32_RS02165 (J0J32_02165)	-	449200..449937 (+)	738	WP_004259087.1	amino acid ABC transporter ATP-binding protein	-
J0J32_RS02170 (J0J32_02170)	murD	450076..451437 (+)	1362	WP_004259085.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56726.70 Da
• Isoelectric Point: 5.1966

>NTDB_id=544582 J0J32_RS02155 WP_004259093.1 445741..447231(+) (covS) [Lactococcus garvieae strain LG728]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESTLS
EENLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTSSHGFPLKKDVGDGTHAVRTFGEYSGYLV
ERPVYSNKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLENIDFQDEDLICDPTEVSNFLKKNFLLIHADLSLTVENNLSPGRLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDHGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
VVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=544582 J0J32_RS02155 WP_004259093.1 445741..447231(+) (covS) [Lactococcus garvieae strain LG728]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACCTTCACTATTTTTACAGTATTGGTTTACCAATTGACCATTACAACCTTCA
TCAATTCTGAAAAAGAGGATATGATGAAAGCTCTGGATAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCACACTGTCG
GAAGAAAATCTGGCGAATTATTTGGCTTATGCCAAAGACTATACAGCCTCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGCTCTAGGAAGTCCTTTTATGTTTTTGACGTCGGTGAAAATTTGATTTACTCGACCAGTTCGC
ATGGCTTCCCTCTAAAAAAAGACGTGGGGGATGGCACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTC
GAACGACCAGTTTATTCTAATAAAACAGGTAAGCTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTATAG
CGTGCGAACAAAGTTACTGATTGCCCTGATTATCTTAGAGATTATTGCTCTCTTTATCGCTCAGTTTGTCGGTTATTTTA
TGGCGAGTCGTTACATCAAGCCTCTAGAACGGTTGCACGATGCAATTACTACACGTGCCAATAACTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGTGATGAAATTGAAGAACTGGCGACTGTTTATAATGACATGATGATCAAGCTTAACGA
TTATGTTGATCAGCAGAAACGTTTTGTTTCTGATGTTAGTCATGAGTTACGTACGCCACTTGCGGTTTTGGATGGTCATT
TGAATCTCTTGAACCGTTGGGGGAAAAACGATCCTGAGGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTGAGT
ACGATGAGAACAATGTTGGAAGAGATGCTTGCATTGGCCCGTCTTGAAAACATTGATTTTCAAGATGAAGACCTTATCTG
TGATCCAACAGAAGTTTCTAATTTCCTTAAGAAAAACTTCCTACTTATCCATGCTGATTTAAGCTTAACTGTGGAAAATA
ACTTGTCACCGGGAAGATTGGCTCATATCTACCCGAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCTATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGATAAATACATTATCACTACGGTTGAGGA
TCATGGCTATGGCATTAGTCAGGAAGATTTAAAACATGTCTTTGAGCGTTTCTTCCGTGCTGATAAAGCGCGAAATCGGG
ATATAGGAGGCACGGGGCTTGGACTGTCTATTATTCAACGCATAGTGGAAAACTATGATGGGGATGTCAGTGTGACTTCT
GTTGTAGGTGAGGGATCGAAATTCACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• ArlS sensor domain (ArlS_N) (52-190)

• HAMP domain (HAMP) (214-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.734	100	0.558