Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   LMF34_RS12190 Genome accession   NZ_CP086678
Coordinates   2553107..2554231 (+) Length   374 a.a.
NCBI ID   WP_248422936.1    Uniprot ID   -
Organism   Escherichia coli strain EFF60     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2548107..2559231
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LMF34_RS12165 mscL 2548233..2548643 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  LMF34_RS12170 trkA 2548773..2550149 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  LMF34_RS12175 rsmB 2550171..2551460 (-) 1290 WP_001308993.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  LMF34_RS12180 fmt 2551506..2552453 (-) 948 WP_248422937.1 methionyl-tRNA formyltransferase -
  LMF34_RS12185 def 2552468..2552977 (-) 510 WP_000114984.1 peptide deformylase -
  LMF34_RS12190 dprA 2553107..2554231 (+) 1125 WP_248422936.1 DNA-protecting protein DprA Machinery gene
  LMF34_RS12195 smg 2554203..2554676 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  LMF34_RS12200 yrdD 2554705..2555247 (+) 543 WP_001129723.1 type I DNA topoisomerase -
  LMF34_RS12205 tsaC 2555252..2555824 (+) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  LMF34_RS12210 aroE 2555829..2556647 (+) 819 WP_001521434.1 shikimate dehydrogenase -
  LMF34_RS12215 yrdB 2556644..2556901 (+) 258 WP_001521433.1 DUF1488 domain-containing protein -
  LMF34_RS12220 yrdA 2556877..2557431 (-) 555 WP_001286217.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40945.87 Da        Isoelectric Point: 6.2655

>NTDB_id=544037 LMF34_RS12190 WP_248422936.1 2553107..2554231(+) (dprA) [Escherichia coli strain EFF60]
MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGNVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=544037 LMF34_RS12190 WP_248422936.1 2553107..2554231(+) (dprA) [Escherichia coli strain EFF60]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCAATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.238

98.663

0.476
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

48.387

82.888

0.401
  dprA Vibrio cholerae strain A1552

48.387

82.888

0.401
  dprA Glaesserella parasuis strain SC1401

44.51

90.107

0.401
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

43.636

88.235

0.385