Detailed information NTG0054342

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: SCAZ3_RS05580
• Genome accession: NZ_AIDX01000001
• Coordinates: 1157389..1157829 (+)
• Length: 146 a.a.
• NCBI ID: WP_003046192.1
• Uniprot ID: -
• Organism: Streptococcus canis FSL Z3-227
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1152389..1162829

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCAZ3_RS05550 (SCAZ3_00925)	-	1154063..1154428 (+)	366	WP_003046179.1	DUF1033 family protein	-
SCAZ3_RS05555 (SCAZ3_00930)	comGA	1154515..1155456 (+)	942	WP_003046182.1	competence type IV pilus ATPase ComGA	Machinery gene
SCAZ3_RS05560 (SCAZ3_00935)	comGB	1155389..1156423 (+)	1035	WP_223824829.1	competence type IV pilus assembly protein ComGB	Machinery gene
SCAZ3_RS05565 (SCAZ3_00940)	comGC/cglC	1156426..1156752 (+)	327	WP_003046186.1	competence type IV pilus major pilin ComGC	Machinery gene
SCAZ3_RS05570 (SCAZ3_00945)	comGD	1156727..1157155 (+)	429	WP_039994748.1	competence type IV pilus minor pilin ComGD	Machinery gene
SCAZ3_RS05575 (SCAZ3_00950)	comGE	1157133..1157408 (+)	276	WP_003046190.1	competence type IV pilus minor pilin ComGE	Machinery gene
SCAZ3_RS05580 (SCAZ3_00955)	comGF	1157389..1157829 (+)	441	WP_003046192.1	competence type IV pilus minor pilin ComGF	Machinery gene
SCAZ3_RS05585 (SCAZ3_00960)	comGG	1157807..1158187 (+)	381	WP_003046193.1	competence type IV pilus minor pilin ComGG	-
SCAZ3_RS05590 (SCAZ3_00965)	comGH	1158237..1159190 (+)	954	WP_003046195.1	class I SAM-dependent methyltransferase	Machinery gene
SCAZ3_RS05595 (SCAZ3_00970)	-	1159249..1160445 (+)	1197	WP_003046198.1	acetate kinase	-
SCAZ3_RS05600 (SCAZ3_00975)	-	1160768..1160974 (+)	207	WP_003046200.1	helix-turn-helix transcriptional regulator	-
SCAZ3_RS05605 (SCAZ3_00980)	-	1161132..1161503 (+)	372	WP_003046201.1	hypothetical protein	-
SCAZ3_RS05610 (SCAZ3_00985)	proC	1161707..1162483 (-)	777	WP_003046203.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16879.42 Da
• Isoelectric Point: 10.5817

>NTDB_id=54342 SCAZ3_RS05580 WP_003046192.1 1157389..1157829(+) (comGF) [Streptococcus canis FSL Z3-227]
MNKRTNRVRAFTFLEALIALLVISGSLLVYQGLTKTLLKHSHYLANHDQDHWLLFSQQLREELDGARFQKVTNNKLYIKK
GKKTLALGQSKSHDFRKSASNGQGYQPMLFGLSHTKIQADQSYVSIKLKWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=54342 SCAZ3_RS05580 WP_003046192.1 1157389..1157829(+) (comGF) [Streptococcus canis FSL Z3-227]
TTGAACAAAAGGACAAATAGGGTTAGAGCGTTTACTTTTTTAGAAGCTTTAATTGCTCTGCTCGTTATATCAGGATCGCT
ATTAGTGTATCAAGGGCTAACTAAAACTCTCCTCAAGCACAGCCACTATCTGGCGAATCATGACCAAGATCATTGGCTTT
TGTTTTCCCAGCAGTTACGTGAAGAATTAGATGGAGCTAGGTTTCAAAAAGTAACAAATAACAAACTCTATATTAAAAAG
GGAAAGAAAACCTTAGCTTTAGGTCAATCTAAAAGCCATGATTTTCGGAAATCAGCTAGTAATGGTCAAGGTTACCAACC
CATGTTATTTGGTCTGTCTCATACTAAAATTCAGGCAGACCAGTCCTATGTTAGCATTAAGTTAAAATGGAAAAGTGGCT
TAGAAAGGACTTTTTATTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	49.286	95.89	0.473
comGF	Streptococcus mutans UA140	48.571	95.89	0.466
comGF	Lactococcus lactis subsp. cremoris KW2	45.652	94.521	0.432
comGF/cglF	Streptococcus pneumoniae TIGR4	45.255	93.836	0.425
comGF/cglF	Streptococcus pneumoniae R6	45.255	93.836	0.425
comGF/cglF	Streptococcus pneumoniae Rx1	45.255	93.836	0.425
comGF/cglF	Streptococcus pneumoniae D39	45.255	93.836	0.425
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411