Detailed information NTG0543116

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: JZI59_RS05915
• Genome accession: NZ_CP071144
• Coordinates: 1239185..1240408 (+)
• Length: 407 a.a.
• NCBI ID: WP_012516520.1
• Uniprot ID: A0AAW3GJZ4
• Organism: Streptococcus equi subsp. equi strain 470_008
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1234185..1245408

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JZI59_RS05890 (JZI59_05890)	-	1234819..1237404 (+)	2586	WP_015898718.1	YfhO family protein	-
JZI59_RS05910 (JZI59_05910)	rlmH	1238496..1238975 (-)	480	WP_012678751.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
JZI59_RS05915 (JZI59_05915)	htrA	1239185..1240408 (+)	1224	WP_012516520.1	trypsin-like peptidase domain-containing protein	Regulator
JZI59_RS05920 (JZI59_05920)	spo0J	1240528..1241301 (+)	774	WP_015898719.1	ParB/RepB/Spo0J family partition protein	Regulator
JZI59_RS05925 (JZI59_05925)	dnaA	1241535..1242887 (+)	1353	WP_012678753.1	chromosomal replication initiator protein DnaA	-
JZI59_RS05930 (JZI59_05930)	dnaN	1243044..1244180 (+)	1137	WP_012678754.1	DNA polymerase III subunit beta	-
JZI59_RS05935 (JZI59_05935)	-	1244258..1244455 (+)	198	WP_012677176.1	DUF951 family protein	-
JZI59_RS05940 (JZI59_05940)	-	1244579..1244941 (+)	363	WP_012678755.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 407 a.a.
• Molecular weight: 42434.01 Da
• Isoelectric Point: 5.4809

>NTDB_id=543116 JZI59_RS05915 WP_012516520.1 1239185..1240408(+) (htrA) [Streptococcus equi subsp. equi strain 470_008]
MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGATTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAAS
PAISNPYINLFGEENDTSAVQKEDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVTSRNEAGETISTNAIQTDAAINP
GNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGIGFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQ
LNIPTSVTSGVVVASTQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKVDIKLTKTT
KDLTKKQ

Nucleotide

• Length: 1224 bp

>NTDB_id=543116 JZI59_RS05915 WP_012516520.1 1239185..1240408(+) (htrA) [Streptococcus equi subsp. equi strain 470_008]
GTGTTAAAATCAAAAAATATATTGAAGCCCTTATGGGTTTTAGCCATTGGATTTTTAGGGGGCTTATTAGCTGCCTTAGT
TGTTAATGGATTTAGTCAGAATTCTCTAACATCTTCAAATGCAAAGGGAGCAACGACAACAAGCAACGTCAGCTTTAATA
ATACAACTGATACAACAAAGGCTGTTAAGGTGGTTCAAGATGCTGTAGTGTCTGTTATTAACTATCAAAAGGCTGCTTCG
CCTGCCATTTCAAATCCTTACATCAATCTTTTCGGAGAAGAAAATGATACCTCAGCAGTACAAAAAGAGGACGAGCTAAG
CATACACAGTGAAGGTTCGGGTGTTGTCTACAAAAAAGAAGGTAATACTGCTTATCTTGTAACCAACAATCATGTTATTG
AGGGAGCTCAACGAATTGAAATTTTAACAGCAGACGGCTCTAAGATCGTTGGAGAACTAGTTGGTGCAGACACTTATTCT
GACCTAGCTGTTGTCAAAGTTGCTGCTGATAAAATCAAAACAATAGCCAAATTTGCAGATTCAACCAAAATTAATGTTGG
AGAGGTAGCCATTGCAATTGGTAGTCCTCTTGGAACAAAATATGCCAACTCAGTGACAGAAGGGATTGTTTCAAGTCTAA
GCCGTACAGTCACTTCAAGAAATGAGGCAGGCGAGACCATCTCAACAAATGCTATCCAAACTGATGCTGCTATCAATCCA
GGTAATTCAGGTGGACCACTCATCAATATTGAAGGCCAGGTTATTGGTATCAACTCAAGTAAAATATCCTCAACACCTAC
TGGTAGCGGCGGAGCCATTGAGGGAATTGGCTTTGCTATTCCATCAAGCGATGTTGTCACCATTATTAACCAACTAGAGT
CTAACGGAGCTGTTATCAGACCAGCCTTAGGCATTACAATGGTAAACTTAAGTAATCTATCAACCAATGCATTGATTCAA
TTGAATATTCCAACAAGCGTTACCAGCGGTGTTGTCGTAGCCTCTACTCAAGATGGCATGCCTGCTCTTGGTAAATTGGA
GCAGTATGATGTCATTACTGAGGTTGACGGTAAAGAAGTCAGCTCAATTAGTGACCTACAAAGTGTCTTATATAGTCATG
AGATTAACGACACCATTAAGGTAACCTTCTACAGAGGAACTGCTAAGAAGAAAGTTGACATCAAATTAACAAAAACAACT
AAGGATCTAACTAAAAAGCAGTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (112-257)

• PDZ domain (PDZ_2) (301-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.275	100	0.614
htrA	Streptococcus gordonii str. Challis substr. CH1	57.855	98.526	0.57
htrA	Streptococcus mitis NCTC 12261	54.66	97.543	0.533
htrA	Streptococcus pneumoniae Rx1	53.634	98.034	0.526
htrA	Streptococcus pneumoniae D39	53.634	98.034	0.526
htrA	Streptococcus pneumoniae R6	53.634	98.034	0.526
htrA	Streptococcus pneumoniae TIGR4	53.634	98.034	0.526