Detailed information NTG0054309

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: SDSE_RS15710
• Genome accession: NC_019042
• Coordinates: 1025957..1026631 (-)
• Length: 224 a.a.
• NCBI ID: WP_003060678.1
• Uniprot ID: A0AAE9R380
• Organism: Streptococcus dysgalactiae subsp. equisimilis AC-2713
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1020957..1031631

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SDSE_RS15685 (S_dysgal_equisimilis_AC2713_1082)	-	1021142..1022419 (-)	1278	WP_015057596.1	pyrimidine-nucleoside phosphorylase	-
SDSE_RS15690 (S_dysgal_equisimilis_AC2713_1083)	-	1022406..1023005 (-)	600	WP_015057597.1	class I SAM-dependent methyltransferase	-
SDSE_RS15695 (S_dysgal_equisimilis_AC2713_1084)	coaA	1023274..1024194 (+)	921	WP_012766986.1	type I pantothenate kinase	-
SDSE_RS15700 (S_dysgal_equisimilis_AC2713_1085)	rpsT	1024248..1024496 (+)	249	WP_009881183.1	30S ribosomal protein S20	-
SDSE_RS15705 (S_dysgal_equisimilis_AC2713_1086)	ciaH	1024654..1025964 (-)	1311	WP_015057598.1	HAMP domain-containing sensor histidine kinase	Regulator
SDSE_RS15710 (S_dysgal_equisimilis_AC2713_1087)	ciaR	1025957..1026631 (-)	675	WP_003060678.1	response regulator transcription factor	Regulator
SDSE_RS15715 (S_dysgal_equisimilis_AC2713_1088)	-	1026835..1029372 (-)	2538	WP_014612305.1	M1 family metallopeptidase	-
SDSE_RS15720 (S_dysgal_equisimilis_AC2713_1089)	phoU	1029573..1030226 (-)	654	WP_003057760.1	phosphate signaling complex protein PhoU	-
SDSE_RS15725 (S_dysgal_equisimilis_AC2713_1090)	pstB	1030304..1031062 (-)	759	WP_003057749.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25601.58 Da
• Isoelectric Point: 4.4684

>NTDB_id=54309 SDSE_RS15710 WP_003060678.1 1025957..1026631(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis AC-2713]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGQKEVQVDGRPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFVDKLQTLRSVGYILKSHE

Nucleotide

• Length: 675 bp

>NTDB_id=54309 SDSE_RS15710 WP_003060678.1 1025957..1026631(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis AC-2713]
ATGATCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGCTTCCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGCTGATTATGACAGCC
AAAGAAAGCCTAGATGATAAGGGACATGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACGGGGAAATTCACGGATAAAAATCTAGCCTTTGGGAATGTCGTAG
TGGATTTAGGGCAAAAAGAAGTTCAAGTGGATGGCCGGCCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTTTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATTTTGTGGACAAACTGCAGACATTGA
GAAGCGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (5-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae D39	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae R6	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae TIGR4	84.615	98.661	0.835
ciaR	Streptococcus mutans UA159	84.163	98.661	0.83
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.326	100	0.388
vicR	Streptococcus mutans UA159	35.443	100	0.375