Detailed information NTG0054275

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SDSE_RS10930
• Genome accession: NC_019042
• Coordinates: 51017..51928 (+)
• Length: 303 a.a.
• NCBI ID: WP_003060893.1
• Uniprot ID: A0AAE9U6L1
• Organism: Streptococcus dysgalactiae subsp. equisimilis AC-2713
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 46017..56928

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SDSE_RS10905 (S_dysgal_equisimilis_AC2713_106)	purE	46517..47005 (+)	489	WP_015057187.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
SDSE_RS10910 (S_dysgal_equisimilis_AC2713_107)	purK	46992..48065 (+)	1074	WP_012766418.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
SDSE_RS10915 (S_dysgal_equisimilis_AC2713_108)	-	48075..49331 (+)	1257	WP_015057188.1	DUF4041 domain-containing protein	-
SDSE_RS10920	-	49324..49533 (+)	210	WP_014611912.1	hypothetical protein	-
SDSE_RS10925 (S_dysgal_equisimilis_AC2713_109)	purB	49582..50874 (+)	1293	WP_003056595.1	adenylosuccinate lyase	-
SDSE_RS10930 (S_dysgal_equisimilis_AC2713_110)	comR	51017..51928 (+)	912	WP_003060893.1	XRE family transcriptional regulator	Regulator
SDSE_RS10935 (S_dysgal_equisimilis_AC2713_112)	ruvB	52147..53145 (+)	999	WP_015057190.1	Holliday junction branch migration DNA helicase RuvB	-
SDSE_RS10940 (S_dysgal_equisimilis_AC2713_113)	-	53280..53711 (+)	432	WP_003059365.1	low molecular weight protein-tyrosine-phosphatase	-
SDSE_RS10945 (S_dysgal_equisimilis_AC2713_114)	-	53740..54141 (+)	402	WP_003049089.1	MORN repeat-containing protein	-
SDSE_RS10950 (S_dysgal_equisimilis_AC2713_115)	-	54138..55913 (+)	1776	WP_003059359.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35995.62 Da
• Isoelectric Point: 4.7392

>NTDB_id=54275 SDSE_RS10930 WP_003060893.1 51017..51928(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis AC-2713]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDRKLQVRESQFDEIFENYYDQLPEEEKIAIDIIQAKFEVYQTGDINFGFNILKEFLPQLKKKTVYNLNE
LLLIDLYLIILVVSNFTNDLFDEEFYKEITERILEQHQYLLLEDLFLLNNILLSCADTSIRLKMFERLKDTLQLSHFIMS
TIQDFQRMPMYCMYEWKLSIFYLKDIKRAETYFSQSLTFTQMTNDSYLAQKLQKEWDKDIHPS

Nucleotide

• Length: 912 bp

>NTDB_id=54275 SDSE_RS10930 WP_003060893.1 51017..51928(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis AC-2713]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGATTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTTATTTTAAGGACTCCGACTTATATGGACGATCGCAAATTACAGGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCTGAGGAGGAAAAAATAGCGATTGATATTATCCAGGCAAAATTTGAAGTTTATCAGACAG
GTGATATTAATTTTGGTTTTAATATTTTAAAAGAATTTCTACCACAACTAAAAAAGAAAACGGTTTATAACTTAAATGAA
TTATTATTAATTGATTTATATTTAATTATTTTAGTTGTTTCTAACTTTACAAATGACCTATTTGATGAGGAATTTTATAA
AGAAATAACGGAGCGAATCTTAGAACAGCATCAATACCTGTTATTAGAAGATTTATTTCTATTAAATAATATTCTTTTAT
CTTGCGCAGATACTTCTATTCGTTTAAAAATGTTTGAACGACTAAAGGATACGTTACAACTCAGCCATTTTATTATGTCA
ACCATTCAAGATTTTCAGCGAATGCCCATGTATTGCATGTATGAATGGAAATTGTCTATCTTTTATTTAAAAGATATTAA
ACGAGCAGAAACTTATTTTAGTCAATCTCTCACGTTTACTCAAATGACTAATGATAGTTATTTGGCACAAAAGCTTCAAA
AAGAATGGGATAAGGATATTCATCCCTCTTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	83.389	99.34	0.828
comR	Streptococcus pyogenes MGAS8232	55.629	99.67	0.554
comR	Streptococcus mutans UA159	46.154	98.68	0.455
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	46.575	96.37	0.449
comR	Streptococcus suis P1/7	37.288	97.36	0.363
comR	Streptococcus suis 05ZYH33	37.288	97.36	0.363