Detailed information NTG0541059

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: JWR96_RS02000
• Genome accession: NZ_CP070856
• Coordinates: 393937..396147 (+)
• Length: 736 a.a.
• NCBI ID: WP_043735587.1
• Uniprot ID: A0AAX4AL50
• Organism: Lactococcus cremoris strain GR0507
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 388937..401147

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JWR96_RS01975 (JWR96_01975)	-	389771..390331 (+)	561	WP_011835699.1	GNAT family N-acetyltransferase	-
JWR96_RS01980 (JWR96_01980)	-	390448..390846 (+)	399	WP_043735595.1	hypothetical protein	-
JWR96_RS01985 (JWR96_01985)	-	390952..391884 (+)	933	WP_043735592.1	ABC transporter ATP-binding protein	-
JWR96_RS01990 (JWR96_01990)	-	391881..393242 (+)	1362	WP_043735590.1	ABC transporter permease	-
JWR96_RS01995 (JWR96_01995)	comEA	393300..393956 (+)	657	WP_043735588.1	helix-hairpin-helix domain-containing protein	Machinery gene
JWR96_RS02000 (JWR96_02000)	comEC	393937..396147 (+)	2211	WP_043735587.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
JWR96_RS02005 (JWR96_02005)	-	396428..397204 (+)	777	WP_014572211.1	alpha/beta hydrolase family protein	-
JWR96_RS02010 (JWR96_02010)	-	397387..397602 (+)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
JWR96_RS02015 (JWR96_02015)	atpB	397649..398362 (+)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
JWR96_RS02020 (JWR96_02020)	atpF	398377..398883 (+)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
JWR96_RS02025 (JWR96_02025)	-	398885..399412 (+)	528	WP_043735583.1	F0F1 ATP synthase subunit delta	-
JWR96_RS02030 (JWR96_02030)	atpA	399600..401102 (+)	1503	WP_014572214.1	F0F1 ATP synthase subunit alpha	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84566.54 Da
• Isoelectric Point: 9.8548

>NTDB_id=541059 JWR96_RS02000 WP_043735587.1 393937..396147(+) (comEC) [Lactococcus cremoris strain GR0507]
MRFLLIKFPLIFLTYLVVLLYFCIFTYNLPLLILFICSILLALSRKYYLMIPILIVFSGFFLLINSLSIRDNENQPKNLS
KIELIPDTIQVNGDLLSFQGRMNGQKYQVYDTLKSLKEKKFYQNLSQNCQLSFTGNLEIPETQRNFNGFDDQKYLASQNI
YRQITIQQITNVEIKKNFDLHTLRRKAIVWTQNHFPKPMSDYMTGLLFGFLSKDFNQMSDIYSSLGIIHLFALSGMQVNF
FIDWFRKILLRMGLTRERVNLVQIPFSIFYAFMTGLSVSVLRALFQKNIRLTSLDNIAVTTLVLMLISPKFLLTTGGQLT
LFYAFVISMLNHPFSNLNGLKKVLTESAVLSLCVLPLLIFDFHIFQPLSILLTIIFGFLFDFMLLPLLLCCFLISFLGFS
LNLNFIFQILEWLVHKVDLPLHYPFVLGKPSSLELIVLFVLIGLFVDSFFHKKRKFFLVGFIFLFFFITKNPMRSSITAV
DIGQGDSIFLQDKFNKENILIDTGGQLALPQKNWQKAQTQSNADKTLIPYLESMGVAHIDQLILTRTDADHVGDFLSLAD
KIKIREIWVSPGELTNSSFVEKLKKAKIPIHVSKVGDKIPIFDSFLQVLSNGYTKKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKKLLQNYPKLQVDVLKVGHHGSKTSSSPEFIKEIHPKLALISVGKANRYGHPNQETLETLAKNQVKTLRTDQKGA
IKLTEVNQQWQIKTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=541059 JWR96_RS02000 WP_043735587.1 393937..396147(+) (comEC) [Lactococcus cremoris strain GR0507]
ATGAGATTTCTATTGATTAAATTTCCCCTGATTTTTCTAACTTATCTTGTTGTGCTCCTTTATTTTTGTATCTTTACTTA
CAATTTACCCTTGCTTATTTTATTTATTTGCTCAATTTTACTAGCTTTATCCAGAAAATATTATCTAATGATTCCGATAT
TAATTGTTTTTTCTGGATTTTTTCTGTTAATCAATAGTCTTAGTATTAGGGATAATGAAAATCAACCAAAAAATCTCTCA
AAAATTGAATTAATTCCAGATACAATCCAAGTCAATGGTGATTTATTGAGTTTTCAGGGGAGAATGAATGGACAAAAATA
TCAAGTCTATGACACATTGAAAAGTCTAAAAGAGAAAAAATTTTATCAGAACTTAAGTCAAAATTGTCAGTTAAGTTTCA
CAGGAAACCTTGAAATACCAGAAACTCAGCGAAATTTTAATGGTTTTGATGACCAAAAATATTTAGCTAGTCAAAATATC
TATCGACAGATTACCATTCAGCAAATTACAAATGTGGAAATAAAAAAGAATTTTGACCTTCATACTTTAAGGCGAAAGGC
AATTGTTTGGACACAAAATCATTTTCCAAAACCGATGAGTGACTATATGACAGGTTTGCTTTTTGGCTTTTTAAGTAAGG
ATTTTAATCAGATGAGCGATATTTACAGCTCTTTAGGAATTATTCATCTTTTTGCTCTATCAGGAATGCAAGTAAATTTT
TTTATTGATTGGTTTCGTAAAATACTTCTTCGCATGGGACTGACGAGAGAAAGAGTGAATCTTGTTCAAATTCCATTTTC
TATTTTTTATGCTTTTATGACGGGATTATCAGTTTCAGTTTTAAGAGCCCTTTTTCAAAAAAATATTCGTCTGACTTCTT
TGGATAATATCGCAGTGACGACATTAGTTTTGATGCTTATAAGTCCAAAATTTTTACTGACGACTGGTGGTCAGCTTACC
TTGTTTTATGCTTTTGTCATTTCGATGCTTAACCATCCTTTTTCTAATTTAAATGGATTGAAAAAAGTGCTGACAGAATC
AGCAGTCCTTTCACTTTGTGTTCTTCCGTTACTCATCTTTGATTTTCATATTTTTCAACCTCTTTCAATATTATTAACAA
TTATATTTGGTTTTCTTTTTGATTTTATGCTGCTCCCGCTGCTTTTATGCTGTTTTCTTATATCATTTTTGGGATTTTCG
CTCAATTTAAACTTTATTTTTCAAATTCTAGAATGGCTAGTTCATAAAGTTGATTTACCCTTACATTACCCCTTTGTTTT
GGGGAAACCTAGTTCACTCGAATTAATTGTTCTATTTGTGTTAATTGGTTTATTCGTAGATTCATTTTTTCATAAAAAAA
GGAAATTTTTTTTAGTTGGATTTATATTTTTATTTTTTTTCATCACTAAAAATCCAATGAGATCAAGCATTACAGCGGTT
GATATCGGACAAGGCGATAGTATTTTTCTACAAGATAAGTTTAATAAAGAAAACATTCTGATTGATACTGGGGGACAACT
TGCTCTTCCTCAAAAAAATTGGCAAAAAGCGCAGACGCAATCGAATGCTGACAAAACGCTTATTCCATATTTAGAATCCA
TGGGGGTGGCTCATATTGACCAACTTATTCTGACTCGTACAGATGCTGACCATGTTGGCGATTTCTTGTCCTTAGCTGAT
AAAATAAAAATAAGAGAAATCTGGGTCAGTCCGGGAGAATTAACCAACAGTAGTTTTGTGGAAAAATTAAAAAAAGCAAA
AATTCCGATTCATGTTAGTAAAGTTGGGGATAAAATTCCGATTTTTGATAGTTTTCTTCAAGTTTTATCAAATGGTTACA
CTAAAAAAGGTGATAATAATGATTCCATAGTGACTTATGGAAACTTTTACCATACAAAATTTCTTTTTACAGGAGATTTG
GAACAAGAAGGAGAAAAAAAGCTTCTACAAAATTATCCCAAATTACAGGTAGATGTGTTAAAAGTGGGGCATCATGGCAG
TAAAACAAGTTCAAGTCCAGAATTCATCAAAGAGATACATCCTAAACTTGCACTAATCTCGGTTGGAAAAGCTAATCGCT
ATGGTCATCCCAATCAAGAAACTTTAGAAACCCTAGCCAAAAATCAGGTAAAGACACTCAGAACTGACCAAAAAGGGGCA
ATAAAATTAACAGAAGTAAATCAGCAGTGGCAAATCAAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (206-446)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

• Domain of unknown function (DUF4131) (DUF4131) (29-171)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	97.826	100	0.978
comEC/celB	Streptococcus mitis SK321	45.749	100	0.461
comEC/celB	Streptococcus mitis NCTC 12261	44.73	100	0.45
comEC/celB	Streptococcus pneumoniae TIGR4	44.669	100	0.45
comEC/celB	Streptococcus pneumoniae Rx1	43.995	100	0.443
comEC/celB	Streptococcus pneumoniae D39	43.995	100	0.443
comEC/celB	Streptococcus pneumoniae R6	43.995	100	0.443