Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   I6J31_RS02490 Genome accession   NZ_CP070515
Coordinates   432453..433583 (-) Length   376 a.a.
NCBI ID   WP_205435611.1    Uniprot ID   -
Organism   Leuconostoc falkenbergense strain FDAARGOS_1201     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 427453..438583
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J31_RS02470 (I6J31_02470) alr 428227..429339 (-) 1113 WP_205435607.1 alanine racemase -
  I6J31_RS02475 (I6J31_02475) - 429733..430554 (+) 822 WP_205435608.1 serine hydrolase -
  I6J31_RS02480 (I6J31_02480) - 430613..431296 (+) 684 WP_205435609.1 NAD(P)H-hydrate epimerase -
  I6J31_RS02485 (I6J31_02485) rlmH 431344..431823 (-) 480 WP_205435610.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6J31_RS02490 (I6J31_02490) htrA 432453..433583 (-) 1131 WP_205435611.1 trypsin-like peptidase domain-containing protein Regulator
  I6J31_RS02495 (I6J31_02495) yycI 433647..434417 (-) 771 WP_244138984.1 two-component system regulatory protein YycI -
  I6J31_RS02500 (I6J31_02500) yycH 434529..435824 (-) 1296 WP_205435613.1 two-component system activity regulator YycH -
  I6J31_RS02505 (I6J31_02505) walK 435814..437679 (-) 1866 WP_205435614.1 cell wall metabolism sensor histidine kinase WalK -
  I6J31_RS02510 (I6J31_02510) yycF 437745..438452 (-) 708 WP_188357284.1 response regulator YycF -

Sequence

Protein


Download         Length: 376 a.a.        Molecular weight: 39049.32 Da        Isoelectric Point: 9.5500

>NTDB_id=540446 I6J31_RS02490 WP_205435611.1 432453..433583(-) (htrA) [Leuconostoc falkenbergense strain FDAARGOS_1201]
MAQSTLTKTVLTGVIAGLVGGGVILYAQEGLEKSTTQTVRTTATKTSSISKNATATTAYNKVSDAVVSVLNFSKSGQNYE
ESSEGSGVIYKKSDQSAFIVTNNHVIDGAAKIQVMLHNGEKVTATLVGKDAMTDLAVLKIASDNVTTTAEFGDSSKIAVG
ENVLAIGSPLGSEYASSVTQGIISAKKRLVEATSENGQNYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLSTSS
SGTSVEGMGFAIPSDQVVDVVNKLVKDGKITRPAIGIGLVNLSEVTADDQKSTLKIPDSVTGGVVVMSLTKKGPADNAGL
KKYDVIVGIDGKKVTTQADLREVLYKHKLGDTITLTYYHHSNKKTVKVKLTQKLAS

Nucleotide


Download         Length: 1131 bp        

>NTDB_id=540446 I6J31_RS02490 WP_205435611.1 432453..433583(-) (htrA) [Leuconostoc falkenbergense strain FDAARGOS_1201]
ATGGCACAATCAACATTAACAAAAACAGTGTTAACTGGCGTCATTGCAGGTTTAGTCGGCGGAGGCGTTATTTTATACGC
GCAAGAGGGGCTTGAAAAAAGTACCACACAAACAGTACGCACAACGGCAACCAAAACGTCGTCGATTTCTAAAAATGCAA
CTGCTACGACAGCTTATAATAAAGTTTCAGATGCGGTCGTGTCTGTGTTGAACTTTAGTAAATCGGGACAGAATTATGAA
GAATCGTCTGAGGGATCTGGTGTCATTTACAAAAAATCAGATCAATCGGCGTTTATTGTGACAAATAATCATGTCATTGA
CGGTGCAGCTAAAATTCAAGTGATGCTCCACAATGGGGAAAAAGTGACTGCCACTTTGGTTGGTAAAGATGCTATGACTG
ACTTAGCGGTTCTAAAGATTGCAAGTGACAATGTGACGACAACAGCTGAGTTTGGTGATTCCAGTAAAATAGCGGTTGGA
GAAAATGTGTTAGCAATTGGCTCTCCTTTGGGCTCAGAGTATGCCTCTTCAGTTACACAAGGCATTATTTCTGCTAAAAA
ACGACTCGTTGAAGCGACTTCTGAAAATGGTCAAAATTACGGTGGCTCGACTGTTATTCAAACGGATGCCGCGATTAATC
CAGGTAATTCTGGTGGTCCGTTGATTAATTTTGCCGGACAAGTGATTGGCATTAATTCAATGAAATTATCTACTTCGTCA
TCAGGCACTAGTGTTGAGGGAATGGGATTTGCGATTCCTTCAGATCAAGTGGTAGACGTTGTCAATAAGTTGGTCAAGGA
CGGCAAAATTACACGGCCAGCCATAGGCATTGGTTTAGTTAATTTGTCAGAAGTGACTGCTGACGATCAAAAGTCTACAC
TCAAAATTCCCGATAGTGTCACAGGCGGTGTTGTGGTCATGAGTTTGACGAAAAAAGGACCGGCTGACAATGCTGGTTTG
AAAAAGTATGATGTGATTGTAGGTATCGATGGCAAGAAAGTGACGACACAAGCCGATCTGCGTGAAGTCCTATACAAACA
CAAATTAGGTGATACGATCACATTGACATACTACCACCACAGTAATAAGAAAACTGTTAAAGTTAAATTAACCCAAAAAT
TAGCAAGCTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(85-231)

PDZ domain (PDZ_2)

(273-370)

Peptidase family M50 (Peptidase_M50)

(218-372)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

52.557

93.617

0.492
  htrA Streptococcus pneumoniae Rx1

52.77

91.223

0.481
  htrA Streptococcus pneumoniae D39

52.77

91.223

0.481
  htrA Streptococcus pneumoniae R6

52.77

91.223

0.481
  htrA Streptococcus pneumoniae TIGR4

52.77

91.223

0.481
  htrA Streptococcus mutans UA159

52.647

90.426

0.476
  htrA Streptococcus gordonii str. Challis substr. CH1

46.597

100

0.473