Detailed information NTG0540237

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: LL045_RS11860
• Genome accession: NZ_CP086083
• Coordinates: 2416756..2417757 (-)
• Length: 333 a.a.
• NCBI ID: WP_003131994.1
• Uniprot ID: Q9CDL3
• Organism: Lactococcus lactis subsp. lactis strain EIP20A
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2411756..2422757

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL045_RS11830 (LL045_11800)	-	2412058..2412495 (-)	438	WP_038602480.1	low molecular weight protein-tyrosine-phosphatase	-
LL045_RS11835 (LL045_11805)	-	2412652..2412804 (-)	153	WP_394530238.1	hypothetical protein	-
LL045_RS11840 (LL045_11810)	-	2412909..2413526 (-)	618	WP_278228190.1	AAA family ATPase	-
LL045_RS11845 (LL045_11815)	-	2413523..2414641 (-)	1119	WP_394530239.1	ABC transporter permease	-
LL045_RS11850 (LL045_11820)	-	2414946..2415515 (-)	570	WP_394530240.1	hypothetical protein	-
LL045_RS11855 (LL045_11825)	-	2415735..2416619 (-)	885	WP_038602487.1	XRE/MutR family transcriptional regulator	-
LL045_RS11860 (LL045_11830)	ruvB	2416756..2417757 (-)	1002	WP_003131994.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
LL045_RS11865 (LL045_11835)	ruvA	2417884..2418477 (-)	594	WP_003131995.1	Holliday junction branch migration protein RuvA	Machinery gene
LL045_RS11870 (LL045_11840)	hexB	2418590..2420560 (-)	1971	WP_394530241.1	DNA mismatch repair endonuclease MutL	Machinery gene
LL045_RS11875 (LL045_11845)	-	2420689..2421384 (-)	696	WP_394530242.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 37633.17 Da
• Isoelectric Point: 4.5825

>NTDB_id=540237 LL045_RS11860 WP_003131994.1 2416756..2417757(-) (ruvB) [Lactococcus lactis subsp. lactis strain EIP20A]
MNDILNKEPMEEDYGIEKSLRPQFFNQYIGQDKVKEQLEIFIKAAKMREEVLDHVLLFGPPGLGKTTMAFVIANELGVNI
KQTAGPAIEKPGDLVAILNELEPGDVLFIDEIHRMPMQVEEVLYSAMEDFYIDIMLGSGDGSRSVHLDLPPFTLVGATTR
AGMLSNPLRARFGISSHMEYYQERDLEEIVKRTADIFEVEVIDNAALEIALRSRGTPRIANRLLKRVRDFAQIMGDGRVD
KAITDKALSILDVDAAGLDYIDQKILRTMIEMYHGGPVGIGTLAVNIAEDRETVEDMYEPYLIQKGFLMRTKQGRKVTQR
AYEHLGYVYNEED

Nucleotide

• Length: 1002 bp

>NTDB_id=540237 LL045_RS11860 WP_003131994.1 2416756..2417757(-) (ruvB) [Lactococcus lactis subsp. lactis strain EIP20A]
ATGAACGATATATTAAACAAAGAGCCAATGGAAGAAGATTACGGTATTGAAAAATCTCTACGTCCGCAATTTTTTAATCA
ATATATTGGTCAAGATAAAGTCAAAGAACAATTAGAAATCTTTATTAAAGCAGCAAAAATGCGTGAAGAAGTTTTGGATC
ACGTATTACTTTTTGGTCCTCCGGGACTTGGTAAGACAACAATGGCATTTGTCATTGCCAATGAGTTGGGAGTTAATATT
AAACAAACAGCGGGTCCTGCCATTGAAAAGCCAGGAGATTTAGTTGCGATTTTGAATGAATTGGAACCTGGCGATGTGCT
ATTTATTGATGAAATTCATCGGATGCCAATGCAAGTTGAAGAAGTTCTTTATAGCGCTATGGAAGATTTCTACATTGATA
TTATGCTTGGTTCTGGTGATGGTTCACGCTCGGTTCATTTAGATTTGCCGCCATTTACTCTAGTTGGGGCAACAACAAGA
GCTGGAATGCTTTCGAATCCATTGCGTGCCCGTTTTGGAATTTCAAGTCATATGGAGTATTATCAAGAGCGTGATTTGGA
AGAAATTGTTAAAAGAACAGCTGATATTTTTGAAGTCGAAGTTATTGATAATGCCGCTTTAGAGATTGCTTTACGTAGTC
GAGGGACTCCGCGGATTGCCAATCGTTTACTTAAACGAGTGCGTGATTTTGCTCAAATAATGGGGGATGGCCGAGTGGAT
AAAGCAATTACCGATAAGGCCTTATCTATTCTTGATGTTGATGCTGCTGGTTTGGATTATATTGACCAAAAAATCCTCCG
CACAATGATTGAAATGTACCACGGTGGTCCTGTTGGGATTGGAACTTTGGCGGTAAATATTGCTGAAGACCGTGAAACGG
TCGAGGATATGTATGAACCTTATTTGATTCAAAAAGGATTTTTGATGAGAACCAAACAGGGACGTAAGGTGACTCAAAGA
GCCTATGAACACCTAGGTTACGTTTATAATGAAGAAGATTGA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

3D structure

• AlphaFold DB: Q9CDL3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	78.614	99.7	0.784
ruvB	Streptococcus pneumoniae D39	78.614	99.7	0.784
ruvB	Streptococcus pneumoniae TIGR4	78.313	99.7	0.781
ruvB	Bacillus subtilis subsp. subtilis str. 168	61.491	96.697	0.595
ruvB	Helicobacter pylori 26695	51.242	96.697	0.495
ruvB	Synechocystis sp. PCC 6803	51.613	93.093	0.48