Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   LL045_RS10195 Genome accession   NZ_CP086083
Coordinates   2105258..2107138 (-) Length   626 a.a.
NCBI ID   WP_270220081.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain EIP20A     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2100258..2112138
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LL045_RS10165 (LL045_10140) - 2100665..2101345 (-) 681 WP_012898438.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -
  LL045_RS10170 (LL045_10145) macP 2101376..2101654 (-) 279 WP_003130796.1 cell wall synthase accessory phosphoprotein MacP -
  LL045_RS10175 (LL045_10150) - 2101647..2102231 (-) 585 WP_012898439.1 NUDIX hydrolase -
  LL045_RS10180 (LL045_10155) glmU 2102336..2103712 (-) 1377 WP_003130798.1 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU -
  LL045_RS10185 (LL045_10160) proC 2103941..2104729 (+) 789 WP_098393257.1 pyrroline-5-carboxylate reductase -
  LL045_RS10190 (LL045_10165) rpsO 2104807..2105076 (-) 270 WP_010906184.1 30S ribosomal protein S15 -
  LL045_RS10195 (LL045_10170) stkP/pknB 2105258..2107138 (-) 1881 WP_270220081.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  LL045_RS10200 (LL045_10175) - 2107138..2107914 (-) 777 WP_038602007.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  LL045_RS10205 (LL045_10180) rsmB 2107995..2109269 (-) 1275 WP_058205240.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  LL045_RS10210 (LL045_10185) - 2109467..2109973 (-) 507 WP_012898444.1 Asp23/Gls24 family envelope stress response protein -
  LL045_RS10215 (LL045_10190) - 2109994..2110182 (-) 189 WP_394530150.1 DUF2273 domain-containing protein -
  LL045_RS10220 (LL045_10195) amaP 2110193..2110753 (-) 561 WP_038602014.1 alkaline shock response membrane anchor protein AmaP -
  LL045_RS10225 (LL045_10200) - 2110781..2111023 (-) 243 WP_038602017.1 GlsB/YeaQ/YmgE family stress response membrane protein -

Sequence

Protein


Download         Length: 626 a.a.        Molecular weight: 67916.14 Da        Isoelectric Point: 4.7476

>NTDB_id=540213 LL045_RS10195 WP_270220081.1 2105258..2107138(-) (stkP/pknB) [Lactococcus lactis subsp. lactis strain EIP20A]
MIQIGKIFADRYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELSHPNIVGISDVG
EFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEIITEILSAMDMAHSHGIIHRDLKPQNVLVSSSGTVKVTDFGIAKA
LSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDGDSAVAIALKHFQESIPSIINLNPEVP
QALENVVIKATAKDIKNRYTDVEEMMTDVATSTSLDRRGEEKLVFNKDHDETKIMPANLINPYDTKPLIDKKEEEDSSTG
EKAISLEKGNKTKKPKKGLIIGLIILLLVVGGATLAWVVSTPTNVKVPNVTNSTLSQAEIKIKAANLKVGTVHKQQSSTI
DEGKVIKTDPDKGTTVRSNSSVDIYLSTGNEDIIKMKDFVGEKIDEAMATLLKDYGIDESQVTQTSVPSDSYPAGTIIKQ
SPKKGSSFDTKGSQKITFEVSSGKQVEVPDYKPNGQYMTYSQYQAALKAAGFTNITLDPQATTNQQADGYVYSVYPNVGT
SVDPTQEIVVTYSVYNAPSSSSTTSESTTTPETSSSSSSSTTTTQSSPENANNSSNKESSTTTSSS

Nucleotide


Download         Length: 1881 bp        

>NTDB_id=540213 LL045_RS10195 WP_270220081.1 2105258..2107138(-) (stkP/pknB) [Lactococcus lactis subsp. lactis strain EIP20A]
ATGATTCAAATCGGTAAAATCTTTGCCGATCGTTATCGGATTATCAAAGAAATCGGACGCGGCGGAATGGCGAACGTTTA
TCAAGGTGAAGATACTTTTCTTGGTGACCGCTTAGTTGCAATAAAAGTGCTACGTTCAAATTTTGAAAATGATGACATTG
CGATTGCTCGTTTTCAGCGAGAAGCATTCGCCATGGCAGAACTTTCACATCCAAATATCGTAGGTATTTCTGACGTTGGT
GAATTTGAAAGTCAACAATACATTGTCATGGAATTTGTTGACGGCATGACACTCAAACAATACATCAATCAAAATGCACC
TTTAGCCAATGATGAAGCTATTGAAATTATTACTGAAATTTTATCAGCAATGGACATGGCCCATTCACATGGTATTATTC
ACCGGGATTTAAAACCACAAAATGTTTTAGTTTCCAGTAGTGGAACTGTAAAAGTAACGGATTTTGGAATTGCGAAAGCA
CTCTCTGAAACTTCACTTACTCAAACAAATACAATGTTTGGTTCGGTTCATTATTTATCACCAGAGCAAGCGCGTGGTTC
AAATGCGACTGTTCAATCAGATATTTATGCGATTGGAATTATTTTATTTGAACTTTTAACAGGTCAAATTCCATTTGATG
GAGATTCAGCAGTTGCTATTGCTCTAAAACATTTCCAAGAGAGTATTCCAAGCATCATTAATCTCAATCCAGAAGTTCCG
CAAGCTTTGGAAAATGTTGTCATTAAAGCTACAGCAAAAGATATTAAAAATCGCTATACTGATGTAGAAGAAATGATGAC
TGATGTGGCAACTTCAACGAGTCTTGACCGTCGTGGGGAAGAAAAATTAGTTTTCAATAAGGATCATGATGAGACTAAAA
TTATGCCTGCTAATTTAATCAATCCATATGATACTAAACCTCTGATTGATAAAAAAGAAGAAGAGGATTCATCAACAGGT
GAAAAAGCTATATCCTTAGAAAAAGGAAATAAAACCAAAAAACCTAAAAAAGGTCTGATTATTGGTCTGATTATTCTCCT
CTTAGTTGTTGGCGGTGCTACTTTGGCTTGGGTTGTATCAACACCAACCAATGTTAAGGTACCCAATGTAACAAATTCCA
CACTTAGTCAAGCTGAAATTAAAATTAAGGCTGCAAACCTTAAAGTGGGAACAGTTCATAAACAGCAAAGTTCAACGATT
GATGAAGGAAAGGTTATTAAAACTGATCCAGATAAAGGGACAACCGTAAGATCCAACAGTTCAGTCGATATTTATCTTTC
CACAGGAAATGAAGATATCATCAAAATGAAGGACTTTGTCGGTGAAAAGATCGATGAGGCGATGGCAACATTACTTAAGG
ATTATGGTATTGATGAAAGCCAAGTCACTCAAACCTCCGTTCCTAGTGATTCTTACCCAGCAGGTACAATCATTAAACAA
AGTCCTAAAAAAGGTTCTAGTTTTGATACCAAAGGGAGTCAAAAAATTACCTTTGAAGTTTCAAGTGGAAAACAAGTTGA
AGTTCCAGATTATAAACCGAACGGTCAATATATGACTTATTCACAGTATCAAGCTGCCTTAAAAGCTGCAGGATTCACTA
ATATTACACTAGATCCTCAAGCGACAACAAATCAACAAGCTGATGGTTATGTTTACTCAGTGTATCCAAATGTAGGAACA
TCTGTTGATCCAACTCAAGAAATTGTAGTCACTTATAGCGTCTATAATGCTCCAAGTTCAAGTTCAACAACTTCTGAATC
AACAACGACGCCTGAAACATCGTCAAGCAGCTCGAGCTCTACAACAACAACTCAGTCATCACCAGAGAATGCTAATAATA
GTAGTAATAAAGAATCTTCAACAACTACATCAAGTAGTTGA

Domains

Predicted by InterProScan.

PASTA domain (PASTA)

(434-501)

PASTA domain (PASTA)

(365-428)

PASTA domain (PASTA)

(506-573)

Protein kinase domain (Pkinase)

(12-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

45.997

100

0.468
  pknB Streptococcus mutans UA159

49.259

86.262

0.425
  stkP Streptococcus pneumoniae TIGR4

48.024

80.831

0.388
  stkP Streptococcus pneumoniae D39

47.826

80.831

0.387
  stkP Streptococcus pneumoniae R6

47.826

80.831

0.387
  stkP Streptococcus pneumoniae Rx1

47.628

80.831

0.385