Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   JRY11_RS04165 Genome accession   NZ_CP070382
Coordinates   801879..803105 (-) Length   408 a.a.
NCBI ID   WP_023189026.1    Uniprot ID   Q66RU0
Organism   Lactococcus lactis strain KF140     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 796879..808105
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JRY11_RS04140 (JRY11_000836) - 797018..797770 (+) 753 WP_010906333.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  JRY11_RS04145 (JRY11_000837) - 797811..798815 (-) 1005 WP_248554364.1 hypothetical protein -
  JRY11_RS04150 (JRY11_000838) - 798957..799181 (-) 225 WP_003130579.1 YkuJ family protein -
  JRY11_RS04155 (JRY11_000839) - 799289..800629 (-) 1341 WP_023189028.1 glycosyltransferase family 4 protein -
  JRY11_RS04160 (JRY11_000840) - 800755..801753 (-) 999 WP_023189027.1 glycosyltransferase family 4 protein -
  JRY11_RS04165 (JRY11_000841) htrA 801879..803105 (-) 1227 WP_023189026.1 S1C family serine protease Regulator
  JRY11_RS04170 (JRY11_000842) rlmH 803481..803960 (+) 480 WP_025017135.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  JRY11_RS04175 (JRY11_000843) - 803979..804677 (+) 699 WP_023189024.1 DNA alkylation repair protein -
  JRY11_RS04180 (JRY11_000844) yajC 804772..805104 (+) 333 WP_003130588.1 preprotein translocase subunit YajC -
  JRY11_RS04185 (JRY11_000845) - 805477..806211 (+) 735 WP_003130589.1 isoprenyl transferase -
  JRY11_RS04190 (JRY11_000846) - 806211..807014 (+) 804 WP_023189023.1 phosphatidate cytidylyltransferase -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 41671.95 Da        Isoelectric Point: 4.9794

>NTDB_id=539588 JRY11_RS04165 WP_023189026.1 801879..803105(-) (htrA) [Lactococcus lactis strain KF140]
MAKANIGKLLLTGVVGGAIALGGSAIYQSTTNQSANNSRSNTTSTKVSNVSVNVNTDVTSAIKKVSNSVVSVMNYQKDNS
QSSDFSSIFGGNSGSSSSTDGLQLSSEGSGVIYKKSGGDAYVVTNYHVIAGNSSLDVLFSGGQKVKASVVGYDEYTDLAV
LKISSEHVKDVATFADSSKLTIGEPAIAVGSPLGSQFANTATEGILSATSRQVTLTQENGQTTNINAIQTDAAINPGNSG
GALINIEGQVIGITQSKITTTEDGSTSVEGLGFAIPSNDVVNIINKLEADGKISRPALGIRMVDLSQLSTNDSSQLKLPS
SVTGGVVVYSVQSGLPAASAGLKAGDVITKVGDTAVTSSTDLQSALYSHNINDTVKVTYYRDGKSNTADVKLSKSTSDLE
TSSSSSSN

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=539588 JRY11_RS04165 WP_023189026.1 801879..803105(-) (htrA) [Lactococcus lactis strain KF140]
ATGGCAAAAGCTAATATAGGAAAATTGCTATTAACAGGTGTCGTGGGCGGAGCCATCGCACTTGGAGGAAGTGCAATCTA
TCAAAGCACTACAAATCAATCGGCAAATAATAGTCGTTCAAATACAACTAGTACAAAGGTTAGTAACGTTTCGGTAAATG
TCAATACCGATGTTACCTCTGCAATTAAAAAAGTTTCAAATTCTGTCGTTTCTGTTATGAATTATCAAAAAGATAACTCA
CAAAGTAGTGACTTCAGTTCAATTTTTGGTGGAAATAGCGGTTCAAGTTCATCGACTGATGGCTTACAGCTTTCTAGTGA
AGGCTCTGGTGTCATCTACAAAAAATCTGGTGGAGATGCCTACGTTGTAACTAACTACCACGTTATTGCTGGTAATAGCT
CACTTGATGTTCTGTTTTCTGGTGGACAAAAAGTCAAAGCTTCTGTGGTTGGTTATGATGAATACACAGACCTTGCTGTT
CTTAAAATCAGTTCTGAACATGTCAAAGATGTGGCGACATTCGCTGATTCTAGTAAATTAACAATTGGTGAACCTGCCAT
TGCCGTTGGCTCACCTTTAGGTAGTCAATTTGCTAACACCGCAACTGAGGGAATTTTATCTGCAACAAGCCGTCAAGTGA
CTTTGACCCAAGAAAATGGTCAAACAACTAATATCAATGCAATTCAAACAGATGCTGCCATTAACCCTGGTAACTCTGGA
GGGGCTTTGATTAATATTGAAGGACAAGTTATTGGAATTACTCAAAGTAAAATTACAACAACTGAAGATGGTTCTACTTC
TGTCGAAGGTTTAGGATTTGCGATTCCTTCTAATGATGTCGTAAATATCATTAATAAACTTGAAGCTGATGGTAAGATTT
CACGCCCTGCTTTAGGTATCCGAATGGTTGACCTTTCACAATTATCAACAAATGACAGTTCTCAATTGAAATTACCAAGC
AGTGTAACAGGTGGAGTTGTTGTTTACTCCGTCCAATCTGGACTTCCTGCTGCCTCAGCTGGTTTGAAAGCTGGAGATGT
AATTACAAAGGTTGGCGATACAGCAGTAACTTCTTCAACAGACTTGCAAAGTGCTCTTTACTCACACAATATCAATGATA
CAGTAAAAGTTACTTATTATCGTGATGGTAAATCAAATACAGCAGATGTTAAACTTTCTAAATCAACCAGTGACTTAGAA
ACAAGCAGTTCATCTTCTTCTAATTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(254-396)

PDZ domain (PDZ_2)

(296-392)

Trypsin-like peptidase domain (Trypsin_2)

(108-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q66RU0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

56.021

93.627

0.525
  htrA Streptococcus gordonii str. Challis substr. CH1

54.22

95.833

0.52
  htrA Streptococcus pneumoniae D39

58.017

84.069

0.488
  htrA Streptococcus pneumoniae TIGR4

58.017

84.069

0.488
  htrA Streptococcus pneumoniae R6

58.017

84.069

0.488
  htrA Streptococcus pneumoniae Rx1

58.017

84.069

0.488
  htrA Streptococcus mutans UA159

52.989

90.196

0.478