Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   LK420_RS05345 Genome accession   NZ_CP085949
Coordinates   1129525..1130646 (+) Length   373 a.a.
NCBI ID   WP_012055334.1    Uniprot ID   -
Organism   Haemophilus influenzae strain FDAARGOS_1562     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1124525..1135646
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LK420_RS05330 (LK420_05330) leuC 1124686..1126095 (-) 1410 WP_011272333.1 3-isopropylmalate dehydratase large subunit -
  LK420_RS05335 (LK420_05335) leuB 1126272..1127348 (-) 1077 WP_021034808.1 3-isopropylmalate dehydrogenase -
  LK420_RS05340 (LK420_05340) leuA 1127434..1128981 (-) 1548 WP_021034807.1 2-isopropylmalate synthase -
  LK420_RS05345 (LK420_05345) dprA 1129525..1130646 (+) 1122 WP_012055334.1 DNA-processing protein DprA Machinery gene
  LK420_RS05350 (LK420_05350) yaaA 1130699..1131475 (+) 777 WP_005666012.1 peroxide stress protein YaaA -
  LK420_RS05355 (LK420_05355) - 1131468..1132007 (+) 540 WP_228003443.1 hypothetical protein -
  LK420_RS05360 (LK420_05360) pfkA 1132103..1133068 (+) 966 WP_021034805.1 6-phosphofructokinase -
  LK420_RS05365 (LK420_05365) smpB 1133308..1133793 (+) 486 WP_005647965.1 SsrA-binding protein SmpB -
  LK420_RS05370 (LK420_05370) fis 1133888..1134187 (-) 300 WP_005651583.1 DNA-binding transcriptional regulator Fis -
  LK420_RS05375 (LK420_05375) dusB 1134181..1135161 (-) 981 WP_041175395.1 tRNA dihydrouridine synthase DusB -

Sequence

Protein


Download         Length: 373 a.a.        Molecular weight: 41639.71 Da        Isoelectric Point: 6.4124

>NTDB_id=539335 LK420_RS05345 WP_012055334.1 1129525..1130646(+) (dprA) [Haemophilus influenzae strain FDAARGOS_1562]
MNDITYTLLRLMQVPKLGGVGIDKILSNITLNELLNYDDVAFRQMGWGAIQIRRWFKPEAKFIEPALAWSQKEGNHLVNY
FSPFYPFLLKQTANFPPLLFVKGNLTALSQRQMAMVGSRYCTTYGEYWAKHFATELSLAGFTITSGLALGIDGHCHQAVV
NIQGQTIAVLGSGLEQIYPSKHQRLSAQIIENNGALVSEFLPNQAPIAANFPRRNRIISGLSVGTLVVEATEKSGSLITA
RYALEQNREVFAVPGNIQNESSQGCHRLIKQGAMLVENAKDILETLYQHSIHSQTEIDFDQIAVPNYTPPPDPRRLVEAP
SHPKLYSRIGYTPVSIDDLAEEFNLSVDVLLVQLLDLELQDLIISENGLYKRV

Nucleotide


Download         Length: 1122 bp        

>NTDB_id=539335 LK420_RS05345 WP_012055334.1 1129525..1130646(+) (dprA) [Haemophilus influenzae strain FDAARGOS_1562]
ATGAATGACATTACCTACACATTACTCCGTTTAATGCAAGTGCCTAAACTTGGCGGCGTTGGCATTGATAAAATTTTGTC
CAATATTACCTTAAATGAATTACTTAATTATGATGATGTTGCTTTCCGACAAATGGGATGGGGAGCCATTCAAATTCGCC
GTTGGTTCAAACCTGAAGCAAAATTTATTGAGCCAGCACTCGCGTGGTCACAAAAAGAGGGAAATCATTTAGTAAATTAT
TTTTCCCCTTTTTATCCCTTTTTATTGAAACAAACCGCAAACTTTCCGCCACTATTATTTGTAAAAGGAAATTTAACCGC
ACTTTCACAACGCCAAATGGCAATGGTTGGGAGCCGTTATTGCACGACTTATGGAGAATATTGGGCAAAACATTTTGCAA
CAGAACTTTCATTAGCGGGTTTTACCATAACAAGCGGTTTAGCATTAGGAATTGATGGTCATTGTCATCAGGCTGTCGTT
AATATTCAAGGGCAAACTATTGCGGTCTTAGGCAGTGGATTAGAACAAATCTATCCCTCTAAACATCAAAGATTATCAGC
ACAAATCATCGAAAATAATGGTGCATTAGTCTCTGAATTTTTACCAAACCAAGCACCTATTGCTGCTAATTTTCCACGCC
GTAATCGGATTATTAGTGGGCTTTCAGTCGGCACGCTTGTTGTTGAAGCCACCGAAAAAAGCGGCTCTCTTATTACTGCG
CGGTATGCGTTGGAACAAAACCGAGAGGTTTTTGCTGTGCCAGGCAATATTCAAAATGAATCAAGTCAAGGTTGTCATCG
CCTGATTAAACAAGGCGCAATGTTGGTAGAAAATGCAAAGGATATTTTGGAAACGCTCTACCAACATTCTATCCACAGCC
AAACTGAAATTGATTTTGACCAGATCGCCGTGCCTAATTACACGCCACCACCCGATCCTCGCCGATTAGTAGAAGCACCA
AGCCACCCGAAACTTTATTCACGTATTGGCTATACTCCTGTGAGCATTGATGATTTAGCTGAAGAATTTAATTTAAGTGT
CGATGTTTTACTTGTTCAATTGCTCGATCTTGAGCTACAAGATCTTATCATAAGTGAAAATGGCTTATATAAACGCGTTT
AA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(311-366)

DNA recombination-mediator protein A (DNA_processg_A)

(71-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Haemophilus influenzae Rd KW20

99.196

100

0.992
  dprA Glaesserella parasuis strain SC1401

52.011

93.298

0.485
  dprA Vibrio campbellii strain DS40M4

43.617

100

0.44
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

43.014

97.855

0.421
  dprA Vibrio cholerae strain A1552

43.014

97.855

0.421
  dprA Legionella pneumophila strain ERS1305867

40.634

93.029

0.378