Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   I6K87_RS05680 Genome accession   NZ_CP069892
Coordinates   1161110..1161865 (-) Length   251 a.a.
NCBI ID   WP_204982457.1    Uniprot ID   -
Organism   Streptococcus anginosus strain FDAARGOS_1357     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1156110..1166865
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K87_RS05660 (I6K87_05660) - 1156541..1157773 (-) 1233 WP_204982456.1 cysteine desulfurase -
  I6K87_RS05665 (I6K87_05665) sufD 1157789..1159051 (-) 1263 WP_059221121.1 Fe-S cluster assembly protein SufD -
  I6K87_RS05670 (I6K87_05670) sufC 1159091..1159861 (-) 771 WP_037567398.1 Fe-S cluster assembly ATPase SufC -
  I6K87_RS05675 (I6K87_05675) - 1159953..1161119 (-) 1167 WP_003028442.1 glycosyltransferase family 4 protein -
  I6K87_RS05680 (I6K87_05680) mecA 1161110..1161865 (-) 756 WP_204982457.1 adaptor protein MecA Regulator
  I6K87_RS05685 (I6K87_05685) csm6 1162953..1164236 (-) 1284 WP_239466777.1 type III-A CRISPR-associated CARF protein Csm6 -
  I6K87_RS05690 (I6K87_05690) csm6 1164243..1165400 (-) 1158 WP_070496952.1 type III-A CRISPR-associated CARF protein Csm6 -
  I6K87_RS05695 (I6K87_05695) csm5 1165397..1166491 (-) 1095 WP_070496949.1 type III-A CRISPR-associated RAMP protein Csm5 -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29105.88 Da        Isoelectric Point: 4.1403

>NTDB_id=537255 I6K87_RS05680 WP_204982457.1 1161110..1161865(-) (mecA) [Streptococcus anginosus strain FDAARGOS_1357]
MEMKQISDTTIKITIKLEDLEERGMEMADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFDDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDMEAVRSLETAEADDNTSTSDTEEQDENSDELTQKYIYYI
LKFSSLKEAIVFSKTVDYTVNTSELYKMDDHYYLTILVDIEGHPKRYPAWLLALMREHAEDTDVTRAVLQEHGYLLLVNE
AVASLKKVKCL

Nucleotide


Download         Length: 756 bp        

>NTDB_id=537255 I6K87_RS05680 WP_204982457.1 1161110..1161865(-) (mecA) [Streptococcus anginosus strain FDAARGOS_1357]
ATGGAAATGAAGCAAATTAGTGATACAACGATTAAAATCACGATAAAATTAGAGGATTTAGAAGAACGTGGAATGGAGAT
GGCAGATTTTCTTGTTCCGCAAGAAAAGACAGAAGAGTTTTTCTATGCAATTTTAGATGAGTTGGAAATGCCAGAGAGCT
TTTTAGATAGTGGCATGCTCAGTTTCCGTGTGACACCAAAGCCTGATCGTTTGGATGTGTTTGTCACCAAGTCTAAGATT
GATAAGAATCTGAATTTTGATGATTTGGCGGATTTGCCAGATGTAGAAGAGCTGTCTCAAATGTCTCCTGATGAATTTTT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGTAAAGACGATATGGAGGCTGTTCGTTCTTTGGAAACGGCGGAAGCAG
ACGATAACACAAGCACTTCTGATACGGAAGAACAAGATGAAAATAGTGACGAGCTAACGCAAAAATATATCTATTACATT
TTGAAATTTTCCAGCCTGAAAGAAGCGATTGTTTTTTCTAAGACAGTAGATTATACTGTTAACACTTCGGAGTTGTACAA
AATGGACGACCATTATTATTTGACAATCTTGGTTGATATTGAAGGGCATCCAAAGCGTTATCCGGCTTGGCTTCTGGCTT
TGATGCGTGAGCATGCAGAAGACACGGATGTGACAAGAGCTGTTTTGCAAGAGCACGGTTACTTATTGCTTGTCAACGAG
GCGGTTGCCAGTCTTAAAAAGGTTAAATGCTTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

65.726

98.805

0.649
  mecA Streptococcus pneumoniae D39

65.726

98.805

0.649
  mecA Streptococcus pneumoniae R6

65.726

98.805

0.649
  mecA Streptococcus pneumoniae TIGR4

65.323

98.805

0.645
  mecA Streptococcus mutans UA159

49.597

98.805

0.49
  mecA Streptococcus thermophilus LMD-9

46.275

100

0.47
  mecA Streptococcus thermophilus LMG 18311

45.882

100

0.466