Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   I6K87_RS04745 Genome accession   NZ_CP069892
Coordinates   969686..971836 (+) Length   716 a.a.
NCBI ID   WP_070671134.1    Uniprot ID   -
Organism   Streptococcus anginosus strain FDAARGOS_1357     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 964686..976836
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K87_RS04720 (I6K87_04720) arcA 964706..965935 (-) 1230 WP_003028185.1 arginine deiminase -
  I6K87_RS04725 (I6K87_04725) - 966244..966930 (-) 687 WP_003040250.1 Crp/Fnr family transcriptional regulator -
  I6K87_RS04730 (I6K87_04730) - 967067..968125 (-) 1059 WP_204982827.1 serine hydrolase -
  I6K87_RS04735 (I6K87_04735) - 968340..968669 (-) 330 WP_003028191.1 hypothetical protein -
  I6K87_RS04740 (I6K87_04740) - 969154..969438 (-) 285 WP_059220523.1 bacteriocin immunity protein -
  I6K87_RS04745 (I6K87_04745) comA/nlmT 969686..971836 (+) 2151 WP_070671134.1 peptide cleavage/export ABC transporter Regulator
  I6K87_RS04750 (I6K87_04750) - 971847..973208 (+) 1362 WP_059220519.1 bacteriocin secretion accessory protein -
  I6K87_RS04755 (I6K87_04755) - 973482..974087 (-) 606 WP_204982828.1 superoxide dismutase -
  I6K87_RS04760 (I6K87_04760) holA 974158..975195 (-) 1038 WP_204982829.1 DNA polymerase III subunit delta -
  I6K87_RS04765 (I6K87_04765) cvfB 975277..976131 (-) 855 WP_003028203.1 RNA-binding virulence regulatory protein CvfB -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 80405.95 Da        Isoelectric Point: 9.6202

>NTDB_id=537246 I6K87_RS04745 WP_070671134.1 969686..971836(+) (comA/nlmT) [Streptococcus anginosus strain FDAARGOS_1357]
MNLKKSFVPQIDARDCGIAALASIARYYGSNYSLAHLRELAKTDKEGTTALGIVKAAKEMGFETRPIQADMTLFETEELP
YPFIVHINKNGNLQHYYVVYKNEKKHLLIGDPDPTVKITKISKKQFAKDWTGVAIFLAPKPSYKPHKDKKNGLASFLPLI
FKQRSLIFYIVLASLLVTLINIVGSYYLQGVLDEYIPNQMKSTLGIISIGLIIAYILQQMMSFSRDYLLTVLSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLSIVMIVGSILLLQNANLFLLTLLAIPIYALI
IFAFMKPFEKMNNDVMQSNAMVNSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLDKTFKLSKYSIMQTALKQGAQFI
LNVVILWVGASLVMSQKISIGQLITFNALLSYFTSPLESIINLQTKLQSAKVANHRLNEVYLVESEFKTKQVLTEKKFLA
GDITFHNVSYKYGFGRDTLSDISLTIKKGDKISLVGVSGSGKTTLAKMIVHFYEPYQGQIRLNGNELKTIDRKVLRQYIN
YLPQQAYIFSGSILENLTLGANQAVSQSDILRACEIAEIRSDIEQMPLGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMKLPDKTIIFVAHRLSISKRTNQIIVLDQGKVIETGSHTELIGRKGFYYHLFNK

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=537246 I6K87_RS04745 WP_070671134.1 969686..971836(+) (comA/nlmT) [Streptococcus anginosus strain FDAARGOS_1357]
GTGAATTTAAAAAAATCGTTTGTGCCGCAAATAGATGCTAGAGATTGTGGTATTGCTGCTCTGGCTTCCATTGCTAGATA
CTATGGTTCAAATTATTCTTTAGCACACTTGAGAGAGCTCGCAAAGACAGACAAAGAAGGGACAACTGCACTTGGAATTG
TCAAAGCAGCAAAAGAAATGGGCTTTGAAACCCGACCAATCCAAGCAGATATGACATTGTTTGAAACAGAAGAGCTTCCC
TATCCTTTCATCGTACATATCAACAAAAATGGCAATCTTCAGCACTATTATGTCGTTTATAAAAACGAGAAAAAGCACTT
GCTTATCGGTGATCCTGATCCAACTGTCAAAATAACTAAGATTAGCAAAAAACAATTTGCAAAAGATTGGACTGGTGTTG
CTATCTTTCTCGCACCGAAACCTAGCTATAAACCTCATAAGGATAAGAAGAACGGGCTTGCTAGCTTTTTACCACTCATC
TTTAAACAGCGTTCTTTGATTTTTTATATTGTCTTAGCTAGTTTGCTCGTGACCCTCATCAACATTGTGGGCTCCTATTA
TCTGCAAGGTGTTTTGGACGAATACATCCCAAATCAGATGAAATCAACTCTTGGGATTATTTCAATTGGGCTTATCATTG
CCTACATCTTACAGCAAATGATGAGTTTTTCAAGAGACTACCTGCTAACAGTTCTCAGTCAACGATTAACAATTGATGTG
ATTTTGTCTTATATTCGGCATATTTTTGAATTACCAATGTCCTTTTTTGCGACGAGACGCACTGGGGAGATTATTTCTCG
TTTTACAGATGCCAACTCCATTATTGATGCTCTAGCTTCAACTATCCTGTCTCTCTTTCTTGATTTGTCCATTGTGATGA
TTGTCGGCAGTATTCTTTTACTGCAAAATGCCAATCTCTTTTTACTCACCTTGCTTGCAATTCCTATCTACGCTCTCATT
ATTTTTGCTTTTATGAAGCCTTTTGAAAAAATGAATAACGATGTTATGCAAAGCAATGCTATGGTAAATTCTGCCATTAT
CGAAGATATCAACGGAATTGAAACCATTAAATCTTTAACCAGCGAAGAAAGCCGTTACCAAAAGATTGATAGCGAGTTTG
TTGATTATCTGGATAAGACTTTCAAATTAAGTAAATATTCTATTATGCAGACAGCACTCAAACAAGGAGCACAATTTATT
TTGAATGTGGTCATTCTCTGGGTTGGAGCTTCTTTAGTCATGTCTCAAAAGATTTCAATTGGTCAGCTGATTACTTTCAA
TGCTCTCCTTTCATACTTTACTAGTCCGCTTGAAAGTATCATCAATCTTCAAACCAAACTGCAATCAGCTAAAGTTGCCA
ATCATCGACTGAATGAAGTTTATCTGGTAGAATCCGAATTCAAAACCAAGCAAGTCCTTACGGAGAAAAAATTCTTAGCT
GGAGACATTACTTTCCATAACGTCTCCTATAAATACGGCTTTGGACGAGATACTTTATCAGATATTAGTTTGACTATCAA
GAAGGGAGATAAAATTAGTCTTGTCGGCGTCAGCGGTTCGGGAAAAACAACACTTGCTAAGATGATTGTTCATTTTTATG
AGCCTTATCAAGGGCAAATTCGCCTCAATGGAAATGAACTCAAGACGATTGACAGGAAAGTTCTTCGGCAATATATCAAC
TACCTGCCTCAGCAAGCTTACATCTTTAGCGGTTCCATTCTAGAAAACCTCACATTAGGAGCCAATCAAGCAGTTTCTCA
ATCAGACATTCTTCGTGCTTGTGAAATTGCAGAAATCCGCTCAGACATTGAACAAATGCCTCTGGGATACCAGACAGAAT
TGTCTGACGGAGCTGGATTATCTGGTGGACAAAAGCAACGAATTGCACTTGCACGCGCTCTGCTGACGAAATCTCCTATT
CTCATTTTAGATGAAGCAACGAGTGGATTAGATGTTTTAACAGAGAAAAAGGTCATTGATAATCTCATGAAATTACCCGA
CAAAACCATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGTACAAATCAGATTATTGTCCTCGACCAAGGAAAAG
TGATTGAAACTGGTTCTCATACTGAATTGATAGGAAGAAAAGGTTTTTATTATCATCTATTTAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(499-648)

Peptidase C39 family (Peptidase_C39)

(5-141)

ABC transporter transmembrane region (ABC_membrane)

(167-437)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.214

99.022

0.715
  comA Streptococcus mitis NCTC 12261

66.48

99.581

0.662
  comA Streptococcus gordonii str. Challis substr. CH1

66.48

99.581

0.662
  comA Streptococcus mitis SK321

66.339

99.581

0.661
  comA Streptococcus pneumoniae Rx1

65.778

99.581

0.655
  comA Streptococcus pneumoniae D39

65.778

99.581

0.655
  comA Streptococcus pneumoniae R6

65.778

99.581

0.655
  comA Streptococcus pneumoniae TIGR4

65.358

99.581

0.651