Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   D1098_RS02935 Genome accession   NZ_CP069797
Coordinates   625869..627071 (+) Length   400 a.a.
NCBI ID   WP_005601207.1    Uniprot ID   Q7BI81
Organism   Actinobacillus pleuropneumoniae strain K17     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 620869..632071
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1098_RS02910 (D1098_02935) folA 621574..622062 (+) 489 WP_005597400.1 type 3 dihydrofolate reductase -
  D1098_RS02915 (D1098_02940) - 622189..622422 (+) 234 WP_005597399.1 YgjV family protein -
  D1098_RS02920 (D1098_02945) radA 622466..623845 (-) 1380 WP_005601211.1 DNA repair protein RadA Machinery gene
  D1098_RS02925 (D1098_02950) pilA 624027..624473 (+) 447 WP_009874618.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  D1098_RS02930 (D1098_02955) pilB 624491..625885 (+) 1395 WP_005615186.1 GspE/PulE family protein Machinery gene
  D1098_RS02935 (D1098_02960) pilC 625869..627071 (+) 1203 WP_005601207.1 type II secretion system F family protein Machinery gene
  D1098_RS02940 (D1098_02965) - 627098..627736 (+) 639 WP_009874617.1 prepilin peptidase -
  D1098_RS02945 (D1098_02970) coaE 627758..628396 (+) 639 WP_009874616.1 dephospho-CoA kinase -
  D1098_RS02950 (D1098_02975) yacG 628378..628566 (+) 189 WP_005597388.1 DNA gyrase inhibitor YacG -
  D1098_RS02955 (D1098_02980) holA 628643..629668 (-) 1026 WP_009874615.1 DNA polymerase III subunit delta -
  D1098_RS02960 (D1098_02985) lptE 629777..630271 (-) 495 WP_005597385.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 45588.09 Da        Isoelectric Point: 10.3239

>NTDB_id=536719 D1098_RS02935 WP_005601207.1 625869..627071(+) (pilC) [Actinobacillus pleuropneumoniae strain K17]
MLKVYEFHWKAKNRFQQLQKGKALACHRTELERRLLAKGYSQIRIQRNFRFVTQASSESITQVIKQLALLLNAAVPLKQA
LNMLLENTYHIRIYMWLNDLNRLIESGYTMSSSLTKLNLYLAKSEIQLVRIGEQSGRLGEILQNIAVNRHQTEKLHKKIK
KIMFYPVVTLIISVALSLAMLLFIVPQFIELYSGREKPLPLITQMLFTLSHFLQHSLLQVTIVSLLAVGFFRFFAKKYRF
LTAIKNGMLSALPIFNKIVENVRIVFFSQNLGLMLKAHIRLETALNTFLAAQSQDLRLQKEIENILAQLKQGYRFSESIN
ASVFGTQVVQMLAIGEQSGNVAQMCSYIGELYRQQLDDQIELLSQLLEPILMLIIGLIIGTVLIGLYLPIFDLGGLVGGG

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=536719 D1098_RS02935 WP_005601207.1 625869..627071(+) (pilC) [Actinobacillus pleuropneumoniae strain K17]
ATGTTGAAAGTGTATGAATTTCATTGGAAAGCTAAAAATCGTTTTCAACAACTTCAGAAAGGAAAAGCGCTAGCTTGTCA
TCGAACGGAATTGGAACGGCGTTTATTAGCAAAAGGCTATTCACAGATCCGTATCCAACGTAATTTTCGTTTTGTCACAC
AGGCTTCTTCAGAATCGATTACTCAAGTAATTAAACAGTTGGCGCTTTTACTGAATGCCGCAGTCCCTTTAAAACAAGCG
CTGAATATGTTGTTAGAAAATACTTATCATATTCGGATCTATATGTGGCTGAATGATTTAAACCGTTTGATAGAATCGGG
TTATACAATGTCGTCAAGTTTAACCAAATTGAATTTATATTTGGCGAAATCGGAAATACAGCTGGTACGGATTGGCGAAC
AAAGCGGGCGATTAGGCGAAATTTTGCAAAATATTGCGGTAAATCGCCATCAAACCGAAAAATTACATAAGAAAATAAAA
AAGATAATGTTTTATCCTGTCGTCACTTTGATTATTTCCGTTGCGCTTTCTCTCGCCATGCTCCTTTTTATCGTGCCGCA
ATTTATCGAGCTGTATTCCGGTCGTGAAAAGCCGCTTCCTTTAATTACACAAATGCTATTTACATTATCGCACTTCTTAC
AACATTCTTTATTACAGGTAACGATAGTCAGTTTATTAGCGGTCGGTTTTTTCCGTTTTTTTGCAAAAAAATATCGATTT
TTAACCGCTATAAAAAACGGGATGTTAAGTGCTTTGCCTATTTTTAATAAGATAGTCGAAAACGTTCGTATAGTATTTTT
TAGTCAAAATCTCGGCTTGATGCTAAAAGCTCATATTCGGCTGGAAACGGCGTTAAATACCTTTCTTGCTGCACAATCGC
AAGATTTGAGGTTACAAAAAGAGATAGAAAATATTTTAGCGCAATTAAAACAAGGTTATCGCTTTTCCGAAAGTATTAAT
GCGAGTGTGTTCGGTACTCAAGTAGTACAAATGCTTGCCATTGGCGAACAGAGTGGGAATGTAGCGCAGATGTGTAGCTA
TATCGGGGAGTTATATCGACAACAATTGGATGATCAGATTGAACTGTTATCGCAGCTGCTTGAGCCGATCTTAATGCTGA
TTATCGGATTAATTATCGGTACGGTTTTGATCGGATTATATTTACCGATTTTTGATTTAGGCGGACTAGTCGGAGGCGGT
TAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q7BI81

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

50.126

99.25

0.498
  pilC Haemophilus influenzae Rd KW20

39.5

100

0.395
  pilC Haemophilus influenzae 86-028NP

38.5

100

0.385