Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   JS559_RS02020 Genome accession   NZ_CP069795
Coordinates   433356..434561 (+) Length   401 a.a.
NCBI ID   WP_237611100.1    Uniprot ID   -
Organism   Actinobacillus pleuropneumoniae strain A-85/14     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 428356..439561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JS559_RS01995 (JS559_02000) folA 429061..429549 (+) 489 WP_005597400.1 type 3 dihydrofolate reductase -
  JS559_RS02000 (JS559_02005) - 429676..429909 (+) 234 WP_005597399.1 YgjV family protein -
  JS559_RS02005 (JS559_02010) radA 429953..431332 (-) 1380 WP_005601211.1 DNA repair protein RadA Machinery gene
  JS559_RS02010 (JS559_02015) pilA 431514..431960 (+) 447 WP_237611099.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  JS559_RS02015 (JS559_02020) pilB 431978..433372 (+) 1395 WP_005601209.1 GspE/PulE family protein Machinery gene
  JS559_RS02020 (JS559_02025) pilC 433356..434561 (+) 1206 WP_237611100.1 type II secretion system F family protein Machinery gene
  JS559_RS02025 (JS559_02030) - 434585..435223 (+) 639 WP_005604550.1 prepilin peptidase -
  JS559_RS02030 (JS559_02035) coaE 435245..435883 (+) 639 WP_115586748.1 dephospho-CoA kinase -
  JS559_RS02035 (JS559_02040) yacG 435865..436053 (+) 189 WP_115589824.1 DNA gyrase inhibitor YacG -
  JS559_RS02040 (JS559_02045) holA 436130..437155 (-) 1026 WP_005612206.1 DNA polymerase III subunit delta -
  JS559_RS02045 (JS559_02050) lptE 437264..437758 (-) 495 WP_005597385.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 401 a.a.        Molecular weight: 45778.32 Da        Isoelectric Point: 10.2885

>NTDB_id=536659 JS559_RS02020 WP_237611100.1 433356..434561(+) (pilC) [Actinobacillus pleuropneumoniae strain A-85/14]
MLKVYEFHWKAKNRFQQLQKGKALACHRTELERRLLAKGYSQIRIQRNFRFVTQASSESITQVIKQLALLLNAAVPLKQA
LNMLLENTYHIRIYMWLNDLNRLIESGYTMSSSLTKLNLYLAKSEIQLVRIGEQSGRLGEILQNIAVNRYQTEKLHKKIK
KIMFYPVVTLIISVALSLAMLLFIVPQFIELYSGREKPLPLITQMLFTLSLFLQHSLLQVTIVSLLAVGFFRFFAKKYRF
LTAIKNGMLSTLPIFNKIVENVRIVFFSQNLGLMLKAHIRLETALNTFLATQSQDLRLQKEIENILAQLKQGYRFSESIN
ASVFGTQVVQMLAIGEQSGNVAQMCSYIGELYRQQLDDQIELLSQLLEPILMLIIGLIIGTVLIGLYLPIFDLGGLVGGG
Q

Nucleotide


Download         Length: 1206 bp        

>NTDB_id=536659 JS559_RS02020 WP_237611100.1 433356..434561(+) (pilC) [Actinobacillus pleuropneumoniae strain A-85/14]
ATGTTGAAAGTGTATGAATTCCATTGGAAAGCTAAAAATCGTTTTCAACAACTTCAGAAAGGAAAAGCGTTAGCTTGTCA
TCGAACGGAATTGGAACGGCGTTTATTAGCAAAAGGCTATTCACAGATCCGTATCCAACGTAATTTTCGTTTTGTCACAC
AGGCTTCTTCAGAATCGATTACTCAAGTAATTAAACAGTTGGCGCTTTTACTGAATGCCGCAGTCCCTTTAAAACAAGCG
CTGAATATGTTGTTAGAAAATACTTATCATATTCGGATCTATATGTGGCTGAATGATTTAAACCGTTTGATAGAATCGGG
TTATACAATGTCGTCAAGTTTAACCAAATTGAATTTATATTTGGCGAAATCGGAAATACAGCTGGTACGGATTGGCGAAC
AAAGCGGGCGATTAGGCGAAATTTTGCAAAATATTGCGGTAAATCGCTATCAAACCGAAAAATTACATAAGAAAATAAAA
AAGATAATGTTTTATCCTGTCGTCACTTTGATTATTTCCGTTGCGCTTTCTCTCGCCATGCTCCTTTTTATCGTGCCGCA
ATTTATCGAGCTGTATTCCGGTCGTGAAAAGCCGCTTCCTTTAATTACACAAATGCTATTTACATTATCGCTCTTCTTAC
AACATTCTTTATTACAGGTAACGATAGTTAGTTTATTAGCGGTCGGTTTTTTCCGTTTTTTTGCAAAAAAATATCGATTT
TTAACCGCTATAAAAAACGGGATGTTAAGTACTTTGCCTATTTTTAATAAGATAGTCGAAAACGTTCGTATAGTATTTTT
TAGTCAAAATCTCGGCTTGATGCTAAAAGCTCATATTCGGCTGGAAACGGCGTTAAATACCTTTCTTGCTACACAATCGC
AAGATTTGAGGTTACAAAAAGAGATAGAAAATATTTTAGCGCAATTAAAACAAGGTTATCGCTTTTCCGAAAGTATTAAT
GCGAGTGTGTTCGGTACTCAAGTAGTACAAATGCTTGCCATTGGCGAACAGAGTGGGAATGTAGCGCAGATGTGTAGCTA
TATCGGGGAGTTATATCGACAACAATTGGATGATCAGATTGAACTGTTATCGCAGCTGCTTGAGCCGATCTTAATGCTGA
TTATCGGATTAATTATCGGTACGGTTTTGATCGGATTATATTTACCGATTTTTGATTTAGGCGGACTAGTCGGAGGCGGT
CAGTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

49.874

99.002

0.494
  pilC Haemophilus influenzae Rd KW20

40

99.751

0.399
  pilC Haemophilus influenzae 86-028NP

39

99.751

0.389