Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   I6J38_RS03580 Genome accession   NZ_CP069558
Coordinates   732075..732776 (-) Length   233 a.a.
NCBI ID   WP_003035055.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1208     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 727075..737776
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J38_RS03560 (I6J38_03560) rnc 728731..729429 (-) 699 WP_003068697.1 ribonuclease III -
  I6J38_RS03565 (I6J38_03565) - 729565..729830 (-) 266 Protein_719 YbaN family protein -
  I6J38_RS03570 (I6J38_03570) vicX 729925..730728 (-) 804 WP_006268738.1 MBL fold metallo-hydrolase Regulator
  I6J38_RS03575 (I6J38_03575) micB 730730..732082 (-) 1353 WP_006268651.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6J38_RS03580 (I6J38_03580) micA 732075..732776 (-) 702 WP_003035055.1 response regulator YycF Regulator
  I6J38_RS03585 (I6J38_03585) - 733077..733409 (-) 333 WP_006268722.1 hypothetical protein -
  I6J38_RS03590 (I6J38_03590) - 733436..734749 (-) 1314 WP_006268747.1 glycosyltransferase family 4 protein -
  I6J38_RS03595 (I6J38_03595) - 734751..735749 (-) 999 WP_020997876.1 glycosyltransferase family 4 protein -
  I6J38_RS03600 (I6J38_03600) ccpA 735841..736845 (-) 1005 WP_003068684.1 catabolite control protein A Regulator

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26868.85 Da        Isoelectric Point: 4.7415

>NTDB_id=535516 I6J38_RS03580 WP_003035055.1 732075..732776(-) (micA) [Streptococcus constellatus strain FDAARGOS_1208]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFNGREALEMFEAERPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=535516 I6J38_RS03580 WP_003035055.1 732075..732776(-) (micA) [Streptococcus constellatus strain FDAARGOS_1208]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATAAAATTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACAGCCTTCAATGGTCGTGAAGCATTAGAGATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCTGAACTGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGCAATGTTCCCATCATCGTTCTTTCTGCC
AAAGACAGTGAATTTGATAAAGTCATTGGTCTCGAAATCGGAGCAGATGACTATATGACAAAGCCGTTTTCTAATCGTGA
GTTACAGGCGCGTGTCAAAGCTATTTTGCGTCGCACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGTGAAGAATTGGATTTAACACAC
CGTGAGTTTGAATTGCTACACCATTTGGCCACGCATATCGGGCAAGTAATGACGCGTGAACATCTACTAGAAACGGTGTG
GGGATATGATTATTTTGGAGATGTTCGGACTGTTGATGTGACAATTCGCCGTTTGAGAGAGAAGATTGAGGATATTCCCA
GCCGACCAGAGTATATTTTAACGCGGCGCGGTGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

83.262

100

0.833
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.415

98.283

0.446
  covR Streptococcus salivarius strain HSISS4

45.217

98.712

0.446
  scnR Streptococcus mutans UA159

36.052

100

0.361