NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	LCF29_RS02640	Genome accession	NZ_CP084096
Coordinates	528048..529172 (+)	Length	374 a.a.
NCBI ID	WP_225343680.1	Uniprot ID	-
Organism	Escherichia coli O78 strain 3
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 523048..534172

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LCF29_RS02615 (LCF29_02615)	mscL	523174..523584 (-)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-
LCF29_RS02620 (LCF29_02620)	trkA	523714..525090 (-)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
LCF29_RS02625 (LCF29_02625)	rsmB	525112..526401 (-)	1290	WP_001313334.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
LCF29_RS02630 (LCF29_02630)	fmt	526447..527394 (-)	948	WP_000004459.1	methionyl-tRNA formyltransferase	-
LCF29_RS02635 (LCF29_02635)	def	527409..527918 (-)	510	WP_000114984.1	peptide deformylase	-
LCF29_RS02640 (LCF29_02640)	dprA	528048..529172 (+)	1125	WP_225343680.1	DNA-protecting protein DprA	Machinery gene
LCF29_RS02645 (LCF29_02645)	smg	529144..529617 (+)	474	WP_000460672.1	DUF494 family protein Smg	-
LCF29_RS02650 (LCF29_02650)	yrdD	529646..530188 (+)	543	WP_001313333.1	type I DNA topoisomerase	-
LCF29_RS02655 (LCF29_02655)	tsaC	530193..530765 (+)	573	WP_024257773.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
LCF29_RS02660 (LCF29_02660)	aroE	530770..531588 (+)	819	WP_000451222.1	shikimate dehydrogenase	-
LCF29_RS02665 (LCF29_02665)	yrdB	531585..531842 (+)	258	WP_001070559.1	DUF1488 domain-containing protein	-
LCF29_RS02670 (LCF29_02670)	yrdA	531818..532372 (-)	555	WP_001286230.1	gamma carbonic anhydrase family protein	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40929.91 Da Isoelectric Point: 6.3366

                                >NTDB_id=534164 LCF29_RS02640 WP_225343680.1 528048..529172(+) (dprA) [Escherichia coli O78 strain 3]

MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSLYGERWGRLFCETLAKRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALHSGSLVTARCA

LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=534164 LCF29_RS02640 WP_225343680.1 528048..529172(+) (dprA) [Escherichia coli O78 strain 3]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATTGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGAAGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT

TGAACATGGTGGGGCACTTGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCACAGTGGTTCGTTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGACCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.78	98.663	0.481
dprA	Glaesserella parasuis strain SC1401	45.104	90.107	0.406
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	49.032	82.888	0.406
dprA	Vibrio cholerae strain A1552	49.032	82.888	0.406
dprA	Haemophilus influenzae Rd KW20	44.51	90.107	0.401
dprA	Legionella pneumophila strain ERS1305867	44.242	88.235	0.39

Detailed information NTG0534164