Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LLNCDO700_RS12170 Genome accession   NZ_CP069179
Coordinates   2367205..2368428 (+) Length   407 a.a.
NCBI ID   WP_259692249.1    Uniprot ID   -
Organism   Lactococcus cremoris strain NCDO700     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2362205..2373428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLNCDO700_RS12145 (LLNCDO700_12100) - 2363320..2364123 (-) 804 WP_011836053.1 phosphatidate cytidylyltransferase -
  LLNCDO700_RS12150 (LLNCDO700_12105) - 2364123..2364857 (-) 735 WP_011836054.1 isoprenyl transferase -
  LLNCDO700_RS12155 (LLNCDO700_12110) yajC 2365208..2365540 (-) 333 WP_011836055.1 preprotein translocase subunit YajC -
  LLNCDO700_RS12160 (LLNCDO700_12115) - 2365635..2366332 (-) 698 Protein_2373 DNA alkylation repair protein -
  LLNCDO700_RS12165 (LLNCDO700_12120) rlmH 2366350..2366829 (-) 480 WP_011836057.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LLNCDO700_RS12170 (LLNCDO700_12125) htrA 2367205..2368428 (+) 1224 WP_259692249.1 S1C family serine protease Regulator
  LLNCDO700_RS12175 (LLNCDO700_12130) - 2368548..2369546 (+) 999 WP_011836059.1 glycosyltransferase family 4 protein -
  LLNCDO700_RS12180 (LLNCDO700_12135) - 2369692..2371032 (+) 1341 WP_011836060.1 glycosyltransferase family 4 protein -
  LLNCDO700_RS12185 (LLNCDO700_12140) - 2371140..2371364 (+) 225 WP_259692248.1 YkuJ family protein -
  LLNCDO700_RS12190 (LLNCDO700_12145) - 2371508..2372512 (+) 1005 WP_011836061.1 hypothetical protein -
  LLNCDO700_RS12195 (LLNCDO700_12150) - 2372569..2373321 (-) 753 WP_011836062.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 41496.98 Da        Isoelectric Point: 5.7726

>NTDB_id=532763 LLNCDO700_RS12170 WP_259692249.1 2367205..2368428(+) (htrA) [Lactococcus cremoris strain NCDO700]
MAKANIGKLLLTGVVGGAIALGGSAIYQSTTNQLGNANRSNTTSTKVSNVSVNVNTDVTSAIKKVSNSVVSVMNYQKQNS
QSDFSSIFGGNSGSSSANDGLQLSSEGSGVIYKKSGGDAYVVTNYHVIAGNSSLDVLLSGGQKVKATVVGYAEYTDLAVL
KISSDHVKDVATFADSSKLTIGEPAIAVGSPLGSQFANTATEGILSATSRQVTLTQENGQTTSINAIQTDAAINPGNSGG
ALINIEGQVIGITQSKITTTEDGSTSVEGLGFAIPSNDVVNIINKLETDGKISRPALGIRMVDLSQLSTNDSSQLKLPSS
VTGGVVVYSVQAGLPAATAGLKAGDVITKVGDTAVTSSTDLQSALYSHNINDTVKVTYYRDGKSATANVKLSKSTSDLET
NSSSSSN

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=532763 LLNCDO700_RS12170 WP_259692249.1 2367205..2368428(+) (htrA) [Lactococcus cremoris strain NCDO700]
ATGGCAAAAGCTAATATAGGAAAATTGCTATTAACCGGTGTTGTGGGTGGAGCTATCGCACTCGGAGGAAGCGCAATTTA
TCAAAGCACTACAAACCAACTAGGAAATGCTAACCGCTCAAATACGACTAGCACAAAGGTTAGTAATGTTTCGGTAAATG
TCAATACCGATGTTACCTCTGCAATTAAAAAAGTTTCAAATTCTGTCGTTTCTGTTATGAATTATCAAAAACAGAATTCA
CAAAGTGATTTTAGTTCAATTTTTGGTGGAAATAGCGGCTCAAGTTCAGCTAATGACGGCTTGCAACTTTCCAGTGAGGG
TTCTGGTGTTATTTACAAAAAATCTGGTGGAGATGCTTACGTGGTCACTAACTATCACGTTATTGCCGGAAATAGTTCCC
TCGATGTTTTACTTTCTGGTGGGCAAAAAGTTAAAGCCACAGTTGTTGGTTATGCTGAATACACTGACCTTGCCGTTCTT
AAAATCAGCTCTGACCATGTTAAAGACGTGGCAACTTTCGCTGATTCAAGCAAGTTAACTATTGGTGAACCAGCTATTGC
AGTCGGCTCACCTTTAGGTAGCCAGTTTGCTAATACTGCAACCGAAGGAATTCTGTCTGCAACAAGTCGTCAAGTCACTT
TGACTCAAGAAAATGGTCAAACAACAAGTATCAATGCGATTCAAACGGATGCTGCCATTAACCCTGGTAACTCAGGTGGA
GCCTTGATTAATATTGAAGGTCAAGTGATTGGTATTACTCAAAGTAAAATCACAACGACTGAAGATGGTTCTACCTCTGT
GGAAGGTTTAGGTTTTGCTATCCCATCTAATGATGTGGTAAACATCATTAATAAACTTGAAACTGATGGTAAGATTTCAC
GTCCTGCCTTAGGTATTCGTATGGTTGACCTATCTCAATTATCAACAAATGATAGTTCTCAACTGAAATTACCTAGCAGC
GTAACTGGTGGAGTGGTTGTCTACTCTGTTCAAGCGGGTCTTCCTGCTGCCACAGCTGGTCTGAAAGCTGGCGATGTGAT
AACGAAGGTGGGAGATACCGCCGTTACTTCATCAACAGACTTACAAAGTGCTCTTTACTCACACAATATTAATGATACTG
TGAAAGTCACCTACTACCGTGATGGTAAATCAGCCACAGCAAATGTCAAACTCTCTAAATCAACAAGCGATTTAGAAACA
AATAGTTCATCTTCTTCTAATTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(250-395)

Trypsin-like peptidase domain (Trypsin_2)

(107-252)

PDZ domain (PDZ_2)

(295-391)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.872

95.823

0.526
  htrA Streptococcus mitis NCTC 12261

55.614

94.103

0.523
  htrA Streptococcus pneumoniae Rx1

57.849

84.521

0.489
  htrA Streptococcus pneumoniae D39

57.849

84.521

0.489
  htrA Streptococcus pneumoniae R6

57.849

84.521

0.489
  htrA Streptococcus pneumoniae TIGR4

57.849

84.521

0.489
  htrA Streptococcus mutans UA159

53.117

90.663

0.482