Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   JOA01_RS00320 Genome accession   NZ_CP069079
Coordinates   55205..56557 (+) Length   450 a.a.
NCBI ID   WP_217374486.1    Uniprot ID   -
Organism   Streptococcus parasuis strain BS26     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 50205..61557
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JOA01_RS00305 (JOA01_00305) - 52261..52431 (+) 171 WP_217374485.1 bacteriocin -
  JOA01_RS00310 (JOA01_00310) - 52452..52619 (+) 168 WP_216806250.1 hypothetical protein -
  JOA01_RS00315 (JOA01_00315) comA 53040..55193 (+) 2154 WP_130555471.1 peptide cleavage/export ABC transporter ComA Regulator
  JOA01_RS00320 (JOA01_00320) comB 55205..56557 (+) 1353 WP_217374486.1 bacteriocin secretion accessory protein Regulator
  JOA01_RS00325 (JOA01_00325) - 56946..57125 (+) 180 WP_024392853.1 hypothetical protein -
  JOA01_RS00330 (JOA01_00330) - 57126..57326 (+) 201 WP_239604410.1 hypothetical protein -
  JOA01_RS00335 (JOA01_00335) - 57343..57534 (+) 192 WP_024392851.1 hypothetical protein -
  JOA01_RS00340 (JOA01_00340) - 57895..58764 (-) 870 WP_217374487.1 cysteine ABC transporter substrate-binding protein -
  JOA01_RS00345 (JOA01_00345) - 58777..59523 (-) 747 WP_217374488.1 amino acid ABC transporter ATP-binding protein -
  JOA01_RS00350 (JOA01_00350) - 59528..60205 (-) 678 WP_024392848.1 amino acid ABC transporter permease -
  JOA01_RS00355 (JOA01_00355) - 60186..60845 (-) 660 WP_217375124.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 50828.40 Da        Isoelectric Point: 4.7189

>NTDB_id=532148 JOA01_RS00320 WP_217374486.1 55205..56557(+) (comB) [Streptococcus parasuis strain BS26]
MDHHLLESAEFYNRRYHNAASRVIIPSCILFLFLILFSIVAKKEMTISTRATVEPVQRLAQIHSISNHQILRNHLFENQE
ISVGDLLVEYQSENEQIQEDKIKENIAVLKNQISQLNVLKKSLESGSNQFEKEDQYGYSQMFKDYCNQLETLASTIDQQN
ATIASQNQAAKQSQLELDKVMHQTEKALADYRELKWAIQSDGVIDEENVGYSIYAQYQVAQSEDAVASQESFIAQIDNQI
SQVETQLASYKLQYASAGVQQSYTNSLDSQSASLEAQYLTKVGQEMTLLSSQLRDLEATLTVQKQAMDKTKIIADQAGVV
HLNTEVEGSMMIPEGTIIAYVYPVLMEAKKMKITAYIPSKDIASISLKDNIQFSIQGRGVKRLALQSNISEIASTAIQTE
AGNFFKVEAETRISTEMAEQLRYGMEGQFVVITGKKTYFQYFIDEFLGKE

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=532148 JOA01_RS00320 WP_217374486.1 55205..56557(+) (comB) [Streptococcus parasuis strain BS26]
ATGGACCATCATCTGTTAGAAAGTGCAGAATTTTACAACAGACGTTATCATAATGCTGCCAGTAGAGTGATTATTCCTAG
TTGTATATTGTTTTTGTTTCTCATTCTTTTTTCAATCGTTGCTAAAAAAGAAATGACCATTTCAACAAGAGCAACCGTAG
AACCTGTACAACGATTAGCACAGATTCACTCAATCAGTAATCATCAGATTCTGAGGAATCATTTATTCGAAAATCAAGAG
ATTTCAGTTGGAGATTTATTAGTAGAATATCAATCAGAGAATGAGCAAATCCAAGAAGACAAGATCAAAGAAAACATAGC
TGTTTTGAAAAATCAGATTTCTCAACTCAATGTCTTGAAGAAAAGTTTAGAATCGGGAAGTAATCAATTTGAGAAAGAAG
ATCAATATGGTTATTCTCAAATGTTTAAGGATTATTGCAATCAATTAGAAACATTGGCAAGTACGATTGACCAACAAAAT
GCAACGATTGCATCTCAAAATCAAGCCGCAAAACAATCACAATTGGAATTGGATAAAGTAATGCATCAAACGGAGAAAGC
CTTAGCAGACTATAGAGAATTGAAATGGGCCATTCAGTCTGATGGTGTCATTGATGAGGAGAATGTTGGCTATTCAATCT
ATGCACAGTATCAGGTAGCACAATCAGAGGATGCAGTTGCCAGTCAAGAATCATTCATCGCTCAAATCGATAATCAAATT
AGTCAAGTAGAGACTCAACTAGCCAGTTATAAATTGCAATATGCCAGTGCAGGAGTGCAACAATCGTATACGAATAGCTT
GGATAGTCAGTCGGCATCGTTGGAAGCTCAATATTTAACCAAGGTTGGTCAGGAAATGACCTTGTTGTCTTCTCAATTAA
GAGACCTAGAAGCGACACTTACGGTTCAAAAACAAGCAATGGATAAGACAAAAATTATTGCTGATCAGGCAGGGGTCGTT
CATTTAAATACAGAAGTTGAGGGCTCAATGATGATTCCAGAAGGAACAATTATTGCATATGTTTATCCAGTTCTAATGGA
AGCTAAGAAAATGAAGATTACAGCATATATTCCTTCGAAAGATATTGCAAGCATCTCATTAAAGGATAATATCCAGTTTT
CAATACAAGGGAGGGGGGTTAAGCGACTAGCACTGCAGTCCAACATATCAGAAATTGCAAGTACTGCCATTCAAACGGAA
GCTGGTAATTTTTTCAAAGTTGAAGCAGAAACCAGAATATCAACAGAAATGGCTGAACAATTGAGGTATGGAATGGAAGG
CCAATTTGTCGTGATTACAGGTAAGAAGACGTATTTTCAATATTTCATAGATGAATTTTTAGGTAAGGAATAG

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(312-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

48.775

99.778

0.487
  comB Streptococcus pneumoniae D39

46.889

100

0.469
  comB Streptococcus pneumoniae R6

46.889

100

0.469
  comB Streptococcus pneumoniae Rx1

46.889

100

0.469
  comB Streptococcus pneumoniae TIGR4

46.444

100

0.464
  comB Streptococcus mitis NCTC 12261

45.556

100

0.456
  comB Streptococcus mitis SK321

45.333

100

0.453