NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	K7X33_RS02230	Genome accession	NZ_CP082355
Coordinates	474803..475927 (+)	Length	374 a.a.
NCBI ID	WP_000228571.1	Uniprot ID	-
Organism	Escherichia coli strain VCSW5
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 469803..480927

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K7X33_RS02205 (K7X33_02205)	mscL	469929..470339 (-)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-
K7X33_RS02210 (K7X33_02210)	trkA	470469..471845 (-)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
K7X33_RS02215 (K7X33_02215)	rsmB	471867..473156 (-)	1290	WP_001308993.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
K7X33_RS02220 (K7X33_02220)	fmt	473202..474149 (-)	948	WP_000004465.1	methionyl-tRNA formyltransferase	-
K7X33_RS02225 (K7X33_02225)	def	474164..474673 (-)	510	WP_000114984.1	peptide deformylase	-
K7X33_RS02230 (K7X33_02230)	dprA	474803..475927 (+)	1125	WP_000228571.1	DNA-protecting protein DprA	Machinery gene
K7X33_RS02235 (K7X33_02235)	smg	475899..476372 (+)	474	WP_000460672.1	DUF494 family protein Smg	-
K7X33_RS02240 (K7X33_02240)	yrdD	476401..476943 (+)	543	WP_001129723.1	type I DNA topoisomerase	-
K7X33_RS02245 (K7X33_02245)	tsaC	476948..477520 (+)	573	WP_001297709.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
K7X33_RS02250 (K7X33_02250)	aroE	477525..478343 (+)	819	WP_000451229.1	shikimate dehydrogenase	-
K7X33_RS02255 (K7X33_02255)	yrdB	478340..478597 (+)	258	WP_001070567.1	DUF1488 domain-containing protein	-
K7X33_RS02260 (K7X33_02260)	yrdA	478573..479127 (-)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40978.88 Da Isoelectric Point: 6.2662

                                >NTDB_id=528331 K7X33_RS02230 WP_000228571.1 474803..475927(+) (dprA) [Escherichia coli strain VCSW5]

MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLSWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=528331 K7X33_RS02230 WP_000228571.1 474803..475927(+) (dprA) [Escherichia coli strain VCSW5]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTCTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT

TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	44.324	98.93	0.438
dprA	Vibrio cholerae strain A1552	44.324	98.93	0.438
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Haemophilus influenzae Rd KW20	44.214	90.107	0.398
dprA	Legionella pneumophila strain ERS1305867	43.363	90.642	0.393

Detailed information NTG0528331