Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   I6I77_RS15625 Genome accession   NZ_CP068132
Coordinates   3183756..3185060 (+) Length   434 a.a.
NCBI ID   WP_015509239.1    Uniprot ID   A0A200IEL7
Organism   Enterococcus casseliflavus strain FDAARGOS_1120     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3178756..3190060
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I77_RS15605 (I6I77_15595) map 3180274..3181032 (-) 759 WP_005234612.1 type I methionyl aminopeptidase -
  I6I77_RS15610 (I6I77_15600) truA 3181075..3181812 (-) 738 WP_060791770.1 tRNA pseudouridine(38-40) synthase TruA -
  I6I77_RS15615 (I6I77_15605) - 3181999..3182859 (-) 861 WP_060791769.1 LEM-3-like GIY-YIG domain-containing protein -
  I6I77_RS15620 (I6I77_15610) rlmH 3182903..3183382 (-) 480 WP_060791768.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6I77_RS15625 (I6I77_15615) htrA 3183756..3185060 (+) 1305 WP_015509239.1 S1C family serine protease Regulator
  I6I77_RS15630 (I6I77_15620) ytpR 3185130..3185744 (-) 615 WP_005225431.1 YtpR family tRNA-binding protein -
  I6I77_RS15635 (I6I77_15625) - 3186322..3186783 (-) 462 WP_005225429.1 universal stress protein -
  I6I77_RS15640 (I6I77_15630) - 3186796..3187116 (-) 321 WP_034857755.1 thioredoxin family protein -
  I6I77_RS15645 (I6I77_15635) pepA 3187250..3188326 (-) 1077 WP_060791847.1 glutamyl aminopeptidase -
  I6I77_RS15650 (I6I77_15640) - 3188619..3188963 (+) 345 WP_005225425.1 peptidase -
  I6I77_RS15655 (I6I77_15645) - 3189024..3190058 (-) 1035 WP_060791767.1 hypothetical protein -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 44863.37 Da        Isoelectric Point: 4.0412

>NTDB_id=527368 I6I77_RS15625 WP_015509239.1 3183756..3185060(+) (htrA) [Enterococcus casseliflavus strain FDAARGOS_1120]
MARKYVTPGKKTSPGLLKRLGIGILGGMVGGLLTFGGLYLAMGSSLTSTPETTTNSGVQDSNGQTQVSNVKLDVTSDVTE
AVEKVQDSVVSIINLQQSQSNDWNSLFGQQGGQSEGDSQSDDDSALEASSEGSGVIYKIDGDDAYVVTNNHVVEGQDGLE
VVLADGTKVKAELVGTDAYTDLAVLKISSEHVKTAATFGDSSALKVGEPAIAIGSPLGSDYANSVTQGIVSSLNRQVTSQ
NESGGTISINAIQTDAAINPGNSGGPLINVDGQVIGINSSKIASTSGSASGVSVEGMGFAIPSNDVVEIINQLEADGKVV
RPALGIQTIDLGSITSQQQEQILKVPSSVTSGVVIYSVNNATPAEQAGLQQYDVITKIDDTEVSTTTDLQSALYKHKVGD
TITVTFYRGDEEKTAEVKLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=527368 I6I77_RS15625 WP_015509239.1 3183756..3185060(+) (htrA) [Enterococcus casseliflavus strain FDAARGOS_1120]
ATGGCAAGAAAATATGTCACACCAGGCAAGAAAACTTCTCCTGGTTTATTAAAACGATTAGGTATTGGGATTTTAGGCGG
TATGGTCGGCGGTTTATTGACCTTCGGCGGTCTGTATCTGGCAATGGGTTCCTCTTTGACTTCAACACCAGAAACCACGA
CCAACAGCGGGGTCCAAGATTCTAACGGACAAACCCAAGTATCCAATGTAAAACTTGATGTGACTAGCGATGTCACTGAG
GCAGTTGAAAAAGTACAAGATTCTGTCGTTTCCATCATTAATCTACAACAAAGTCAAAGCAACGACTGGAACAGCCTCTT
TGGTCAGCAAGGCGGACAAAGTGAAGGCGATAGCCAAAGCGATGACGACAGTGCTTTAGAAGCTTCTTCTGAAGGGAGTG
GGGTCATCTACAAAATCGATGGTGACGATGCCTATGTTGTAACCAACAACCACGTCGTAGAAGGTCAAGACGGTTTAGAA
GTTGTTTTAGCAGACGGTACGAAAGTCAAAGCTGAATTGGTCGGTACTGACGCTTACACAGACTTGGCTGTATTGAAAAT
CTCTTCAGAGCATGTGAAGACTGCCGCAACATTTGGTGATTCAAGTGCCTTGAAAGTCGGCGAACCAGCAATCGCAATCG
GCTCTCCTCTCGGCTCTGACTACGCAAACTCTGTGACACAAGGGATCGTTTCTTCCTTGAATCGTCAAGTAACAAGCCAA
AACGAATCTGGTGGTACGATCAGCATCAATGCGATCCAAACGGATGCTGCGATCAACCCAGGGAACTCAGGTGGTCCACT
GATCAACGTTGATGGTCAAGTGATTGGGATCAACTCAAGTAAAATCGCCAGCACCTCTGGCTCTGCTTCAGGTGTTAGTG
TGGAAGGGATGGGCTTTGCGATCCCAAGTAACGATGTCGTTGAAATCATCAATCAACTAGAAGCAGACGGCAAAGTGGTT
CGCCCTGCACTAGGGATCCAAACGATCGATTTAGGTTCCATCACATCACAACAACAAGAACAAATCTTGAAAGTTCCTTC
ATCCGTAACTTCTGGCGTTGTGATCTACTCAGTCAACAATGCAACACCAGCAGAACAAGCAGGATTGCAACAATATGACG
TTATCACGAAGATCGATGACACAGAAGTCAGCACAACAACGGATCTGCAATCTGCGTTGTACAAACACAAAGTCGGTGAC
ACGATCACTGTAACCTTCTATCGTGGCGATGAAGAAAAAACGGCAGAAGTAAAACTTTCCGTTGATACGTCGATCAACGA
ACAATCAACAGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(132-277)

Peptidase family M50 (Peptidase_M50)

(18-420)

PDZ domain (PDZ_2)

(322-419)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A200IEL7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.171

91.475

0.514
  htrA Streptococcus gordonii str. Challis substr. CH1

51.074

96.544

0.493
  htrA Streptococcus mitis NCTC 12261

55.432

82.719

0.459
  htrA Streptococcus pneumoniae TIGR4

57.018

78.802

0.449
  htrA Streptococcus pneumoniae Rx1

57.018

78.802

0.449
  htrA Streptococcus pneumoniae D39

57.018

78.802

0.449
  htrA Streptococcus pneumoniae R6

57.018

78.802

0.449