Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   I6I79_RS11270 Genome accession   NZ_CP068126
Coordinates   2193250..2194554 (-) Length   434 a.a.
NCBI ID   WP_008379110.1    Uniprot ID   A0A242CMI6
Organism   Enterococcus casseliflavus strain FDAARGOS_1122     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2188250..2199554
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I79_RS11240 (I6I79_11240) - 2188255..2189289 (+) 1035 WP_087627107.1 hypothetical protein -
  I6I79_RS11245 (I6I79_11245) - 2189350..2189694 (-) 345 WP_115232055.1 hypothetical protein -
  I6I79_RS11250 (I6I79_11250) pepA 2189987..2191063 (+) 1077 WP_034870266.1 glutamyl aminopeptidase -
  I6I79_RS11255 (I6I79_11255) - 2191197..2191517 (+) 321 WP_016613643.1 thioredoxin family protein -
  I6I79_RS11260 (I6I79_11260) - 2191530..2191991 (+) 462 WP_005225429.1 universal stress protein -
  I6I79_RS11265 (I6I79_11265) ytpR 2192567..2193181 (+) 615 WP_005225431.1 YtpR family tRNA-binding protein -
  I6I79_RS11270 (I6I79_11270) htrA 2193250..2194554 (-) 1305 WP_008379110.1 S1C family serine protease Regulator
  I6I79_RS11275 (I6I79_11275) rlmH 2194928..2195407 (+) 480 WP_008379108.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6I79_RS11280 (I6I79_11280) - 2195451..2196311 (+) 861 WP_201688640.1 LEM-3-like GIY-YIG domain-containing protein -
  I6I79_RS11285 (I6I79_11285) truA 2196498..2197235 (+) 738 WP_201688641.1 tRNA pseudouridine(38-40) synthase TruA -
  I6I79_RS11290 (I6I79_11290) map 2197278..2198036 (+) 759 WP_005234612.1 type I methionyl aminopeptidase -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 44857.36 Da        Isoelectric Point: 4.0123

>NTDB_id=527287 I6I79_RS11270 WP_008379110.1 2193250..2194554(-) (htrA) [Enterococcus casseliflavus strain FDAARGOS_1122]
MARKYVTPGKKTSPGLLKRLGIGILGGMVGGLLTFGGLYLAMGSSLTSTPETTTNSGVQDSNGQTQVSNVKLDVTSDVTE
AVEKVQDSVVSIINLQQSQSNDWNSLFGQQGGQSEGDSQSEDDSALEASSEGSGVIYKIDGDDAYVVTNNHVVEGQDGLE
VVLADGTKVKAELVGTDSYTDLAVLKISSEKVTTAATFGDSSALKVGEPAIAIGSPLGSDYANSVTQGIVSSLNRQVTSQ
NESGGTISINAIQTDAAINPGNSGGPLINVDGQVIGINSSKIASTSGSASGVSVEGMGFAIPSNDVVEIINQLEADGKVV
RPALGIQTIDLGSITSQQQEQILKVPSSVTSGVVIYSVNNATPAEQAGLQQYDVITKIDDTEVSTTTDLQSALYKHKVGD
TITVTFYRGDEEKTAEVKLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=527287 I6I79_RS11270 WP_008379110.1 2193250..2194554(-) (htrA) [Enterococcus casseliflavus strain FDAARGOS_1122]
ATGGCAAGAAAATATGTCACACCAGGTAAGAAAACTTCTCCTGGTTTATTAAAACGATTAGGTATTGGGATTTTAGGCGG
TATGGTCGGCGGTTTATTGACCTTCGGCGGTCTGTATCTGGCAATGGGTTCCTCTTTGACTTCAACACCAGAAACCACGA
CCAACAGCGGGGTCCAAGATTCTAACGGACAAACCCAAGTATCCAATGTAAAACTTGATGTGACTAGCGATGTCACTGAG
GCAGTTGAAAAAGTACAAGATTCTGTCGTTTCCATCATTAATCTACAACAAAGTCAAAGCAACGACTGGAACAGCCTCTT
TGGTCAGCAAGGTGGACAAAGTGAAGGCGATAGCCAAAGCGAAGACGACAGCGCCTTAGAAGCTTCTTCTGAAGGGAGTG
GTGTCATCTACAAAATCGATGGCGACGATGCCTATGTCGTAACCAACAACCACGTCGTTGAAGGTCAAGATGGTTTGGAA
GTTGTCTTAGCAGATGGTACAAAAGTCAAAGCTGAATTGGTAGGTACCGATTCTTACACAGACTTAGCCGTCTTAAAAAT
CTCTTCTGAAAAAGTTACAACTGCCGCAACATTTGGCGATTCAAGTGCCTTGAAAGTCGGCGAACCAGCAATCGCGATCG
GTTCTCCTCTAGGCTCTGACTATGCAAACTCTGTGACACAAGGGATCGTTTCTTCCTTGAATCGTCAAGTAACAAGCCAA
AACGAATCTGGTGGTACGATCAGTATCAATGCGATCCAAACGGATGCTGCGATCAACCCAGGGAACTCAGGTGGTCCACT
GATCAACGTTGATGGTCAAGTGATTGGGATCAACTCAAGTAAAATCGCCAGCACCTCTGGCTCTGCTTCAGGTGTTAGTG
TCGAAGGGATGGGCTTTGCGATCCCAAGTAACGATGTCGTTGAAATCATCAATCAACTAGAAGCAGACGGCAAAGTGGTC
CGCCCTGCACTAGGTATCCAAACGATCGATTTAGGTTCCATCACATCACAACAACAAGAACAAATCTTGAAAGTTCCTTC
ATCCGTAACTTCAGGCGTTGTGATTTACTCAGTCAACAATGCAACACCAGCAGAACAAGCAGGACTGCAACAATATGACG
TTATCACGAAGATCGATGACACAGAAGTCAGCACCACAACGGATCTACAATCTGCGTTGTACAAACACAAAGTCGGTGAC
ACGATCACTGTAACCTTCTATCGTGGCGATGAAGAAAAAACAGCAGAAGTAAAACTTTCCGTTGATACATCGATCAACGA
ACAATCAACAGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(18-420)

PDZ domain (PDZ_2)

(322-419)

Trypsin-like peptidase domain (Trypsin_2)

(132-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A242CMI6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.927

91.475

0.521
  htrA Streptococcus gordonii str. Challis substr. CH1

51.074

96.544

0.493
  htrA Streptococcus mitis NCTC 12261

55.989

82.719

0.463
  htrA Streptococcus pneumoniae TIGR4

57.602

78.802

0.454
  htrA Streptococcus pneumoniae D39

57.602

78.802

0.454
  htrA Streptococcus pneumoniae Rx1

57.602

78.802

0.454
  htrA Streptococcus pneumoniae R6

57.602

78.802

0.454