Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   K6972_RS00375 Genome accession   NZ_CP082203
Coordinates   62113..63012 (+) Length   299 a.a.
NCBI ID   WP_222812612.1    Uniprot ID   -
Organism   Streptococcus suis strain NJ3     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 57113..68012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6972_RS00345 (K6972_00345) - 57676..58353 (-) 678 WP_222759586.1 amino acid ABC transporter permease -
  K6972_RS00350 (K6972_00350) - 58334..58993 (-) 660 WP_074391045.1 amino acid ABC transporter permease -
  K6972_RS00355 (K6972_00355) ruvB 59121..60119 (+) 999 WP_222759588.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  K6972_RS00360 (K6972_00360) - 60131..60865 (+) 735 WP_222759590.1 GNAT family N-acetyltransferase -
  K6972_RS00365 (K6972_00365) - 60867..61502 (+) 636 WP_222812610.1 HAD-IA family hydrolase -
  K6972_RS00370 (K6972_00370) tnpA 61538..61899 (+) 362 Protein_54 IS200/IS605 family transposase -
  K6972_RS00375 (K6972_00375) comR 62113..63012 (+) 900 WP_222812612.1 helix-turn-helix domain-containing protein Regulator
  K6972_RS00380 (K6972_00380) - 63229..64449 (+) 1221 WP_222812613.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  K6972_RS00385 (K6972_00385) - 64640..66163 (+) 1524 WP_222812615.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35448.31 Da        Isoelectric Point: 4.3188

>NTDB_id=527101 K6972_RS00375 WP_222812612.1 62113..63012(+) (comR) [Streptococcus suis strain NJ3]
MNDKEFGQRVRQLRESANMTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMEKRADMMTEIYDEYYDDLPEEEKIAIDAIQSIIDVFETKTAEFGQDILEDYFEQIQRKNQFSAND
LLIIRLYLINLRMEIKQSSDFQHFLELVEKLPSQVELIESGELFILRDVMLTSIGILGEHEEYGKIPPLFDALDRIMVST
QDFQKKPILNLLKWKYELYVNNDSEEARRFYEEAVMFAKLIGDSHLVEKLESSWREEEK

Nucleotide


Download         Length: 900 bp        

>NTDB_id=527101 K6972_RS00375 WP_222812612.1 62113..63012(+) (comR) [Streptococcus suis strain NJ3]
ATGAACGATAAGGAATTTGGACAACGTGTGCGCCAGCTGCGAGAATCAGCCAATATGACGCGTGAACAGTTTTGTGATGA
TGAACTGGAGCTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCAGATTATGTGTCTCTGCCTGAACGATATTCCAAACTGAAG
TTTGATGTACTCCGTACACCGACTTATGAAAATGAGGAATTGATGGAAAAACGGGCAGATATGATGACAGAAATCTATGA
TGAATATTATGATGACTTGCCTGAAGAAGAGAAAATAGCGATTGATGCCATTCAATCTATTATTGATGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAAATCCAAAGAAAAAACCAATTTTCAGCCAATGAT
TTGTTGATAATTCGACTCTATTTAATCAATTTGAGAATGGAAATTAAACAGAGCAGTGATTTTCAGCACTTTTTAGAGTT
GGTGGAAAAGTTACCAAGCCAAGTAGAATTGATTGAATCTGGAGAATTATTTATTTTAAGAGATGTGATGCTGACGTCGA
TAGGGATTCTTGGCGAACATGAAGAATATGGCAAGATACCTCCACTTTTTGATGCTCTAGATAGAATTATGGTTTCAACT
CAAGATTTTCAAAAGAAACCCATTCTCAATCTGCTTAAGTGGAAATATGAGTTGTATGTGAACAATGATAGCGAGGAGGC
TAGACGGTTTTATGAAGAAGCAGTTATGTTCGCAAAATTAATAGGAGACTCCCATTTAGTAGAAAAATTAGAATCATCAT
GGAGAGAAGAGGAAAAGTGA

Domains

Predicted by InterProScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

68.475

98.662

0.676
  comR Streptococcus suis 05ZYH33

68.475

98.662

0.676
  comR Streptococcus suis D9

61.873

100

0.619
  comR Streptococcus mutans UA159

41.806

100

0.418
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.542

96.321

0.371
  comR Streptococcus pyogenes MGAS8232

37.374

99.331

0.371