Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   I6J12_RS10940 Genome accession   NZ_CP068060
Coordinates   2249471..2250493 (+) Length   340 a.a.
NCBI ID   WP_020999446.1    Uniprot ID   -
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2244471..2255493
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS10915 (I6J12_10915) - 2245613..2246143 (+) 531 WP_003033434.1 FUSC family protein -
  I6J12_RS10920 (I6J12_10920) - 2246220..2246579 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  I6J12_RS10925 (I6J12_10925) glnA 2246618..2247964 (+) 1347 WP_003033463.1 type I glutamate--ammonia ligase -
  I6J12_RS10930 (I6J12_10930) - 2248153..2248518 (+) 366 WP_003033468.1 DUF1033 family protein -
  I6J12_RS10935 (I6J12_10935) comYA 2248588..2249529 (+) 942 WP_003033431.1 competence type IV pilus ATPase ComGA Machinery gene
  I6J12_RS10940 (I6J12_10940) comYB 2249471..2250493 (+) 1023 WP_020999446.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6J12_RS10945 (I6J12_10945) - 2250571..2252010 (-) 1440 WP_003038160.1 recombinase family protein -
  I6J12_RS10950 (I6J12_10950) - 2252188..2252403 (-) 216 WP_003038243.1 hypothetical protein -
  I6J12_RS10955 (I6J12_10955) - 2252454..2253188 (-) 735 WP_003038240.1 helix-turn-helix domain-containing protein -
  I6J12_RS10960 (I6J12_10960) - 2253345..2253548 (+) 204 WP_003038241.1 helix-turn-helix transcriptional regulator -
  I6J12_RS10965 (I6J12_10965) - 2253684..2253830 (+) 147 WP_003038244.1 BOW99_gp33 family protein -
  I6J12_RS10970 (I6J12_10970) - 2253870..2254202 (+) 333 WP_003038177.1 hypothetical protein -
  I6J12_RS10975 (I6J12_10975) - 2254427..2255119 (+) 693 WP_003038151.1 ERF family protein -
  I6J12_RS10980 (I6J12_10980) - 2255143..2255463 (+) 321 WP_003038223.1 hypothetical protein -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 39275.37 Da        Isoelectric Point: 9.5497

>NTDB_id=526827 I6J12_RS10940 WP_020999446.1 2249471..2250493(+) (comYB) [Streptococcus anginosus strain FDAARGOS_1155]
MQQDISILNKQNRKKLSTVKQKKVVELLNNLFSSGFHLAEMIDFLKRSALLEEVYVDRMKEGLSTGKPFSDIMASLGFSD
NVVTQLSLAELHGNLSLSLSKIEEYLENISKVKKKLIEVATYPFILFIFLVFIMLGLRNYLLPQLESQNIATQLISRLPQ
IFLGSVGVVFALFAIGFYWFRKRSQIRVFSLLSRLPFWGTFIQTYLTAYYAREWGNMIGQGLELSQIFQMMQGQRSAMFQ
EIGKDLEVALQNGQEFSQVVKHYPFFKKELGLMIEYGEVKSKLGCELEVYAQKTWEVFFKRVHQAMNIIQPLVFVFVALM
IVLLYAAMLLPIYQNMEVQL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=526827 I6J12_RS10940 WP_020999446.1 2249471..2250493(+) (comYB) [Streptococcus anginosus strain FDAARGOS_1155]
ATGCAGCAGGACATATCAATCTTGAACAAGCAGAATCGGAAAAAATTATCCACGGTTAAGCAGAAAAAGGTCGTAGAGTT
GCTGAATAATCTTTTTTCTAGCGGCTTTCATTTAGCAGAAATGATCGACTTTTTGAAGCGAAGTGCCTTGTTAGAAGAAG
TCTATGTGGACAGGATGAAAGAGGGTTTGTCAACAGGAAAGCCTTTTTCGGACATTATGGCAAGCTTAGGTTTTTCGGAT
AATGTAGTAACACAGCTTTCATTAGCGGAATTGCATGGAAATTTATCGCTCAGTTTGAGTAAAATTGAAGAGTATTTGGA
AAATATCTCAAAAGTCAAGAAAAAGTTAATTGAAGTGGCGACTTATCCATTTATTTTATTCATTTTTCTAGTGTTTATTA
TGTTAGGACTGCGCAATTATTTGTTACCGCAGTTGGAGAGTCAGAATATTGCAACACAACTGATTAGTCGTTTACCACAA
ATTTTTCTGGGTTCAGTAGGAGTTGTTTTTGCTTTGTTTGCGATAGGTTTTTATTGGTTTAGAAAAAGATCACAAATAAG
AGTATTTAGTTTGTTGTCTCGACTTCCTTTTTGGGGCACTTTTATTCAAACCTATTTGACAGCTTATTATGCGAGAGAAT
GGGGAAATATGATTGGTCAAGGCTTAGAACTCAGTCAGATTTTCCAGATGATGCAAGGACAGCGCTCTGCTATGTTTCAA
GAGATTGGAAAAGATTTAGAAGTAGCACTGCAAAATGGTCAGGAATTTTCACAAGTAGTTAAGCATTATCCATTTTTTAA
AAAAGAATTGGGGTTGATGATTGAATATGGGGAAGTGAAATCCAAATTGGGGTGCGAATTAGAAGTTTATGCTCAAAAAA
CGTGGGAGGTGTTTTTTAAACGTGTTCATCAAGCGATGAATATCATTCAGCCATTAGTATTTGTCTTTGTGGCGTTGATG
ATTGTATTGTTGTATGCGGCCATGTTGCTGCCAATTTATCAAAATATGGAGGTTCAATTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

72.647

100

0.726
  comGB/cglB Streptococcus mitis NCTC 12261

68.358

98.529

0.674
  comGB/cglB Streptococcus mitis SK321

68.06

98.529

0.671
  comGB/cglB Streptococcus pneumoniae TIGR4

67.463

98.529

0.665
  comGB/cglB Streptococcus pneumoniae R6

67.463

98.529

0.665
  comGB/cglB Streptococcus pneumoniae Rx1

67.463

98.529

0.665
  comGB/cglB Streptococcus pneumoniae D39

67.463

98.529

0.665
  comYB Streptococcus mutans UA140

60.526

100

0.609
  comYB Streptococcus mutans UA159

60.526

100

0.609
  comGB Lactococcus lactis subsp. cremoris KW2

51.335

99.118

0.509