Detailed information NTG0526746

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: I6J14_RS07900
• Genome accession: NZ_CP068057
• Coordinates: 1566579..1567490 (-)
• Length: 303 a.a.
• NCBI ID: WP_003049081.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain FDAARGOS_1157
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1561579..1572490

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J14_RS07875 (I6J14_07875)	-	1562580..1564355 (-)	1776	WP_003049091.1	acyltransferase family protein	-
I6J14_RS07880 (I6J14_07880)	-	1564352..1564753 (-)	402	WP_003049089.1	MORN repeat-containing protein	-
I6J14_RS07885 (I6J14_07885)	-	1564782..1565213 (-)	432	WP_003049087.1	low molecular weight protein-tyrosine-phosphatase	-
I6J14_RS07890 (I6J14_07890)	ruvB	1565348..1566346 (-)	999	WP_003049085.1	Holliday junction branch migration DNA helicase RuvB	-
I6J14_RS07895 (I6J14_07895)	comS	1566397..1566492 (-)	96	WP_198455558.1	quorum-sensing system DWW-type pheromone	Regulator
I6J14_RS07900 (I6J14_07900)	comR	1566579..1567490 (-)	912	WP_003049081.1	XRE family transcriptional regulator	Regulator
I6J14_RS07905 (I6J14_07905)	purB	1567632..1568924 (-)	1293	WP_115252494.1	adenylosuccinate lyase	-
I6J14_RS07910 (I6J14_07910)	purK	1568934..1570019 (-)	1086	WP_115252493.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
I6J14_RS07915 (I6J14_07915)	purE	1570006..1570494 (-)	489	WP_003049074.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
I6J14_RS07920 (I6J14_07920)	purD	1570749..1572011 (-)	1263	WP_003049071.1	phosphoribosylamine--glycine ligase	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35627.22 Da
• Isoelectric Point: 4.5798

>NTDB_id=526746 I6J14_RS07900 WP_003049081.1 1566579..1567490(-) (comR) [Streptococcus dysgalactiae strain FDAARGOS_1157]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDGKLQVRESQFDEIFENYYDQLPEEEKLIIECLQATLDTLLSENINFGVELLQEYFKQTKVKLRFKQND
LILIELYLAYLDIEGMYGEYSDKVFYDSLLDNLLKQFDDFELDELFIVNKIIIDISSLSIKTNKLDNLEKTIAISQKIMA
KIQDWNRMPILKLIEWKYFLIKQKNRKQAEESYTKACLFAQITGDKYLEEQLIKEWEKDICAY

Nucleotide

• Length: 912 bp

>NTDB_id=526746 I6J14_RS07900 WP_003049081.1 1566579..1567490(-) (comR) [Streptococcus dysgalactiae strain FDAARGOS_1157]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGACTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTATGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCAAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGTGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATGGGAAATTGCAAGTCCGAGAGTCTCAGTTTGATGAGATATTCGA
AAACTATTATGATCAATTGCCCGAGGAGGAAAAATTGATTATAGAATGTTTACAGGCTACGCTAGACACTTTATTGAGTG
AAAACATCAATTTTGGTGTTGAATTATTGCAGGAATATTTTAAACAAACCAAAGTTAAGCTACGTTTTAAACAAAACGAC
TTGATACTTATTGAACTCTATCTGGCTTATCTCGATATTGAAGGGATGTATGGAGAATATTCTGATAAGGTTTTTTATGA
TTCTTTGTTAGATAACCTGTTAAAACAATTCGATGACTTTGAATTAGACGAACTGTTCATAGTTAATAAAATTATTATTG
ATATTTCTTCTTTAAGTATTAAAACTAATAAACTAGATAATCTAGAAAAGACGATTGCTATAAGTCAAAAAATCATGGCA
AAAATTCAGGATTGGAATAGAATGCCTATACTAAAATTAATAGAATGGAAGTACTTTTTAATAAAGCAAAAGAACAGAAA
ACAAGCAGAGGAATCATATACAAAGGCGTGTCTGTTTGCGCAGATAACAGGAGACAAGTATTTGGAAGAGCAATTAATTA
AAGAATGGGAGAAAGATATTTGTGCTTATTAA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (12-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	82.838	100	0.828
comR	Streptococcus pyogenes MGAS315	55.333	99.01	0.548
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	50.847	97.36	0.495
comR	Streptococcus mutans UA159	49.164	98.68	0.485