Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   I6J15_RS02450 Genome accession   NZ_CP068056
Coordinates   490943..491236 (-) Length   97 a.a.
NCBI ID   WP_020915991.1    Uniprot ID   -
Organism   Streptococcus lutetiensis strain FDAARGOS_1158     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 485943..496236
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J15_RS02410 (I6J15_02410) - 486257..486892 (-) 636 WP_111712559.1 CPBP family intramembrane glutamic endopeptidase -
  I6J15_RS02415 (I6J15_02415) - 486907..487362 (-) 456 WP_231853254.1 ABC transporter permease -
  I6J15_RS02420 (I6J15_02420) - 487363..487563 (-) 201 WP_058814360.1 hypothetical protein -
  I6J15_RS02425 (I6J15_02425) - 487580..487777 (-) 198 WP_020915996.1 helix-turn-helix transcriptional regulator -
  I6J15_RS02430 (I6J15_02430) - 487937..489136 (-) 1200 WP_020915995.1 acetate kinase -
  I6J15_RS02435 (I6J15_02435) comYH 489190..490146 (-) 957 WP_020915994.1 class I SAM-dependent methyltransferase Machinery gene
  I6J15_RS02440 (I6J15_02440) comGG 490200..490550 (-) 351 WP_020915993.1 competence type IV pilus minor pilin ComGG -
  I6J15_RS02445 (I6J15_02445) comYF 490522..490959 (-) 438 WP_043894883.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6J15_RS02450 (I6J15_02450) comYE 490943..491236 (-) 294 WP_020915991.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6J15_RS02455 (I6J15_02455) comYD 491190..491621 (-) 432 WP_020915990.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6J15_RS02460 (I6J15_02460) comYC 491605..491898 (-) 294 WP_020915989.1 competence type IV pilus major pilin ComGC Machinery gene
  I6J15_RS02465 (I6J15_02465) comYB 491898..492941 (-) 1044 WP_020915988.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6J15_RS02470 (I6J15_02470) comYA 492865..493806 (-) 942 WP_020915987.1 competence type IV pilus ATPase ComGA Machinery gene
  I6J15_RS02475 (I6J15_02475) - 493878..494246 (-) 369 WP_020915986.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10823.60 Da        Isoelectric Point: 6.4795

>NTDB_id=526665 I6J15_RS02450 WP_020915991.1 490943..491236(-) (comYE) [Streptococcus lutetiensis strain FDAARGOS_1158]
MVTIKKQKLKAYILLEGLVALALLATIISLVLGEMDRSRTQMQESLHQQEVLNVATMAVQTGQDHLAINGVEVRMVKHDN
EISVYDGQNEVLHVTKN

Nucleotide


Download         Length: 294 bp        

>NTDB_id=526665 I6J15_RS02450 WP_020915991.1 490943..491236(-) (comYE) [Streptococcus lutetiensis strain FDAARGOS_1158]
GTGGTAACTATAAAAAAACAGAAACTAAAAGCTTACATACTCCTTGAGGGCTTGGTAGCTCTTGCTTTATTAGCAACGAT
TATCAGTCTGGTCTTAGGAGAAATGGACCGTAGTCGCACTCAAATGCAAGAGAGTTTGCATCAGCAAGAAGTACTTAATG
TAGCGACCATGGCCGTTCAAACAGGACAAGACCATTTGGCCATTAATGGGGTTGAGGTGCGTATGGTTAAGCATGATAAT
GAGATTTCCGTTTATGATGGGCAAAATGAGGTGCTGCATGTCACGAAAAATTAG

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

51.042

98.969

0.505
  comYE Streptococcus mutans UA159

51.042

98.969

0.505
  comGE/cglE Streptococcus pneumoniae Rx1

42.391

94.845

0.402
  comGE/cglE Streptococcus pneumoniae D39

42.391

94.845

0.402
  comGE/cglE Streptococcus pneumoniae R6

42.391

94.845

0.402
  comGE/cglE Streptococcus pneumoniae TIGR4

42.391

94.845

0.402
  comGE/cglE Streptococcus mitis SK321

41.304

94.845

0.392
  comGE/cglE Streptococcus mitis NCTC 12261

41.304

94.845

0.392