Detailed information NTG0526668

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: K6968_RS04785
• Genome accession: NZ_CP082198
• Coordinates: 970875..972860 (-)
• Length: 661 a.a.
• NCBI ID: WP_012028187.1
• Uniprot ID: A0A0H3N3Z6
• Organism: Streptococcus suis strain Transconjugant cNJ3
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 965875..977860

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6968_RS04775 (K6968_04775)	-	968896..968994 (-)	99	Protein_893	UvrB/UvrC motif-containing protein	-
K6968_RS04780 (K6968_04780)	-	969037..970860 (-)	1824	WP_014636397.1	DUF2971 domain-containing protein	-
K6968_RS04785 (K6968_04785)	uvrB	970875..972860 (-)	1986	WP_012028187.1	excinuclease ABC subunit UvrB	Machinery gene
K6968_RS04790 (K6968_04790)	-	973058..975256 (+)	2199	WP_222760838.1	ABC transporter substrate-binding protein/permease	-
K6968_RS04795 (K6968_04795)	-	975256..975996 (+)	741	WP_002940438.1	amino acid ABC transporter ATP-binding protein	-
K6968_RS04800 (K6968_04800)	-	976250..976741 (-)	492	WP_011922516.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 661 a.a.
• Molecular weight: 75592.64 Da
• Isoelectric Point: 4.5993

>NTDB_id=526668 K6968_RS04785 WP_012028187.1 970875..972860(-) (uvrB) [Streptococcus suis strain Transconjugant cNJ3]
MINRNTENQFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILMGATGTGKTYTMSQVIARVNKPTLVIAHNKTLAGQLYS
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYS
DSVVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREIESLTGKVL
GDVDHLAIFPATHFVTNDDHMETAIAKIQAELEEQLKVFEAEGKLLEAQRLKQRTDYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPEDYLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEMEQTETVVEQIIRPTGLLDPEVEVRPTMGQMDDLLGEINARVEKGERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADK
VTESMRKAMEETARRRQIQMAYNEEHGIIPQTIKKEIRDLISVTKAVTQDKEEVVDFNALNKDERKAMIKKLEGQMQEAA
EVLDFELAAQIRDMVIELKNM

Nucleotide

• Length: 1986 bp

>NTDB_id=526668 K6968_RS04785 WP_012028187.1 970875..972860(-) (uvrB) [Streptococcus suis strain Transconjugant cNJ3]
ATGATCAATCGAAATACTGAAAACCAATTTAAACTTGTGTCAAAATATGCACCGTCTGGTGACCAGCCCCAAGCCATTGA
AACCTTGGTTGATAACATCGAGGGGGGCGAAAAAGCCCAGATTCTCATGGGGGCGACTGGTACTGGTAAGACCTATACCA
TGAGCCAGGTTATCGCCCGTGTCAATAAGCCAACCTTGGTCATCGCCCACAACAAGACCTTGGCTGGTCAGCTTTATAGT
GAGTTCAAGGAATTCTTTCCAGAAAATGCGGTCGAATACTTCGTGTCTTACTATGATTACTACCAGCCAGAAGCTTATGT
ACCGTCTAGCGATACCTATATCGAAAAGGATAGTTCGGTCAATGATGAGATTGACAAACTCCGTCACTCTGCGACCTCAG
CTCTGCTAGAACGCAATGATGTCATTGTGGTAGCTTCTGTTTCTTGTATCTACGGTTTGGGTTCACCCAAGGAATATTCA
GATAGCGTGGTCAGCCTGCGACCAGGTCAGGAGATTTCCCGTGATCAGTTGCTCAATGCCTTGGTGGATATCCAGTTTGA
GCGGAACGACATCGACTTCCAACGGGGACGGTTCCGTGTGCGTGGCGATGTGGTGGAGATTTTCCCAGCTTCCCGTGACG
AACATGCCTTTCGTGTGGAGTTTTTCGGGGATGAAATCGACCGCATTCGTGAGATTGAAAGCCTGACAGGCAAGGTTTTG
GGCGATGTGGACCACTTGGCCATTTTCCCTGCCACCCACTTCGTGACCAACGATGACCACATGGAAACGGCCATTGCCAA
GATTCAGGCGGAACTAGAAGAGCAACTCAAGGTCTTTGAGGCAGAAGGAAAACTCTTAGAAGCTCAGCGATTGAAACAAC
GAACCGACTACGATATCGAGATGCTTCGGGAGATGGGCTATACCAACGGAGTTGAGAACTATTCACGACACATGGACGGG
CGAAGTGAGGGGGAGCCTCCTTATACCCTGCTGGACTTTTTCCCTGAGGACTATCTGATTATGATTGACGAGAGCCACAT
GACCATGGGGCAGATTAAGGGGATGTACAATGGTGACCGCTCACGCAAGGAGATGCTGGTTAACTATGGTTTCCGTCTAC
CGAGTGCATTGGATAATCGTCCGCTGCGCAGGGAAGAATTTGAGAGTCATGTCCACCAGATTGTCTATGTATCTGCGACG
CCGGGTGACTATGAAATGGAGCAGACAGAGACCGTTGTCGAGCAGATTATCCGGCCGACCGGGCTTTTGGATCCAGAAGT
GGAAGTCCGTCCAACTATGGGCCAAATGGACGACCTCCTAGGTGAAATCAATGCCCGTGTTGAAAAAGGCGAGCGAACCT
TTATCACTACCCTGACCAAGAAAATGGCAGAGGACTTGACCGACTACCTGAAAGAAATGGGCGTCAAGGTCAAGTATATG
CACTCGGACATCAAGACCTTGGAGCGTACGGAGATTATCCGTGATCTTCGCTTGGGTGTCTTTGATGTTTTGATAGGGAT
TAACCTGCTTCGTGAAGGGATTGACGTGCCAGAAGTTAGTCTAGTCGCTATCTTAGACGCAGACAAGGAGGGCTTCCTCC
GTAATGAACGGGGGCTCATCCAGACAATCGGTCGAGCGGCTCGTAACTCTGAAGGTCATGTGATTATGTATGCGGACAAG
GTCACCGAGTCCATGCGGAAGGCCATGGAAGAAACAGCCCGCCGCCGTCAAATCCAGATGGCTTATAATGAAGAGCATGG
CATTATTCCACAGACCATTAAGAAAGAGATCCGTGACCTGATTAGCGTGACCAAGGCTGTCACTCAGGACAAGGAAGAGG
TTGTGGACTTCAATGCTCTTAATAAAGATGAACGCAAGGCCATGATCAAGAAACTGGAAGGTCAGATGCAGGAAGCCGCA
GAAGTGCTTGACTTTGAACTGGCAGCCCAGATTCGCGATATGGTCATTGAGTTGAAGAATATGTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• Type III restriction enzyme, res subunit (ResIII) (21-143)

• UvrB/uvrC motif (UVR) (626-660)

• UvrB interaction domain (UvrB_inter) (164-254)

• Helicase conserved C-terminal domain (Helicase_C) (445-549)

3D structure

• AlphaFold DB: A0A0H3N3Z6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	91.225	100	0.912
uvrB	Streptococcus pneumoniae D39	91.225	100	0.912
uvrB	Streptococcus pneumoniae TIGR4	91.074	100	0.911