Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   JJN14_RS08045 Genome accession   NZ_CP067992
Coordinates   1614877..1616790 (-) Length   637 a.a.
NCBI ID   WP_201058370.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V7-A3     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1609877..1621790
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS08025 (JJN14_08025) - 1611020..1612294 (-) 1275 WP_201058367.1 hydroxymethylglutaryl-CoA reductase, degradative -
  JJN14_RS08030 (JJN14_08030) - 1612294..1613466 (-) 1173 WP_201058368.1 hydroxymethylglutaryl-CoA synthase -
  JJN14_RS08035 (JJN14_08035) - 1613579..1614028 (-) 450 WP_025171133.1 threonine/serine exporter family protein -
  JJN14_RS08040 (JJN14_08040) - 1614030..1614788 (-) 759 WP_201058369.1 threonine/serine exporter family protein -
  JJN14_RS08045 (JJN14_08045) stkP 1614877..1616790 (-) 1914 WP_201058370.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  JJN14_RS08050 (JJN14_08050) - 1616787..1617527 (-) 741 WP_070479797.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  JJN14_RS08055 (JJN14_08055) rsmB 1617542..1618855 (-) 1314 WP_201058371.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  JJN14_RS08060 (JJN14_08060) fmt 1618848..1619783 (-) 936 WP_201058372.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 637 a.a.        Molecular weight: 69702.37 Da        Isoelectric Point: 9.2971

>NTDB_id=526169 JJN14_RS08045 WP_201058370.1 1614877..1616790(-) (stkP) [Streptococcus mitis strain S022-V7-A3]
MIQIGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHHPLSNEEAIRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSSLSNNRRNEPKLVFDDATKADTKTLPKVPQSTLTSIPKAPVQEGRPQSK
PQPHQTEKPVPSPKPTKRRRLKARYPILFATFLLVVASLVWILYRTPATIAVPKVAGQTVAEAKEALKKANFEVGEEKTE
ASDKVEEGRVIRTDPDAGTTRKEGTKINLIVSSGQQSFQLGNYLGRKSSDVVAELKGKKVPENLIMIEEEESNEIEAGTI
MKQSLPEGTTYDLSKATQIVLTVAKKVNSISMPSYIGSTREFAVNNLTEIYGIKKANIEVVEVSTAPEGTAEETVVEQSP
KPGGKIDLASTRIKISIYKPKTPPSSSSSTSVPRGNQGSPTTPNQGNQQGGHQGNQQGTVPTPTQPNSEGNHENSRD

Nucleotide


Download         Length: 1914 bp        

>NTDB_id=526169 JJN14_RS08045 WP_201058370.1 1614877..1616790(-) (stkP) [Streptococcus mitis strain S022-V7-A3]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGAATTATCAAACAAATTGGTCGAGGAGGCATGGCAGATGTCTA
TTTGGCCAAGGATTTGATTTTGGACGGTGAAGAAGTGGCAGTAAAGGTTCTGAGGACCAACTACCAGACAGACCCGATTG
CTGTGGCTCGTTTTCAGCGGGAAGCGAGAGCCATGGCAGATTTGGACCATCCTCATATCGTTCGGATTACAGATATCGGT
GAAGAAGAGGGACAACAGTATCTCGCAATGGAATATGTTGCTGGGTTAGATCTCAAACGCTATATCAAGGAACATCACCC
TCTTTCAAATGAAGAAGCGATTCGAATCATGGGACAAATCCTTCTGGCTATGCGCTTAGCCCATACTCGAGGGATTGTTC
ACAGGGATTTGAAACCGCAAAATATCCTTTTGACCCCAGATGGGACTGCCAAAGTTACAGACTTTGGAATCGCAGTAGCC
TTTGCAGAGACAAGTCTGACTCAGACCAACTCAATGCTAGGTTCCGTTCATTATTTGTCTCCAGAGCAGGCGCGTGGTTC
TAAAGCAACTGTGCAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGCTGACAGGTCATATTCCTTACGATG
GGGATAGTGCGGTGACCATCGCCCTCCAGCATTTCCAGAAACCACTGCCATCGGTTATAGCTGAAAATCCATCTGTGCCT
CAGGCTTTAGAAAATGTTGTTATCAAGGCAACTGCCAAGAAATTGACCGATCGCTACAAATCAGTCGCTGAGATGTATGT
GGACTTGTCGAGTAGTTTATCTAATAATCGTCGTAATGAACCAAAGCTGGTCTTTGACGATGCAACTAAGGCAGATACTA
AAACTCTTCCTAAAGTTCCACAAAGTACGCTGACTTCTATTCCTAAAGCTCCGGTACAAGAGGGAAGACCTCAATCTAAG
CCCCAGCCTCATCAGACAGAAAAACCAGTACCTAGTCCAAAGCCAACCAAACGGCGTCGCCTGAAAGCACGTTATCCAAT
TTTATTTGCGACCTTCTTGTTAGTTGTGGCATCCTTGGTATGGATTTTATATAGAACGCCCGCTACCATTGCCGTTCCAA
AGGTGGCAGGTCAGACGGTTGCTGAGGCTAAAGAAGCGCTTAAGAAAGCCAATTTTGAGGTTGGTGAAGAAAAAACAGAG
GCTAGTGATAAGGTTGAAGAAGGTCGTGTTATTCGTACCGATCCTGACGCCGGTACGACACGCAAAGAAGGAACAAAAAT
TAATTTGATTGTGTCTTCTGGTCAGCAATCCTTCCAACTTGGAAATTATCTTGGACGAAAATCTAGTGATGTAGTGGCAG
AATTGAAAGGCAAGAAGGTTCCAGAAAATCTAATTATGATTGAGGAAGAAGAATCCAACGAAATCGAAGCTGGTACAATC
ATGAAACAAAGTTTACCGGAGGGAACAACCTATGATCTTAGCAAGGCAACTCAAATAGTTCTGACTGTTGCTAAAAAAGT
AAATTCTATTTCAATGCCAAGTTATATTGGTTCAACTCGAGAATTTGCAGTTAATAATCTTACAGAGATATATGGAATTA
AAAAAGCTAATATCGAAGTTGTAGAAGTGTCTACTGCTCCTGAAGGAACAGCTGAGGAGACTGTTGTAGAGCAAAGTCCA
AAACCGGGTGGAAAAATTGATTTAGCCAGCACACGTATTAAAATTTCGATTTATAAACCCAAAACACCACCATCAAGTTC
CTCTTCAACGTCAGTTCCACGTGGTAACCAAGGTTCACCTACTACTCCAAATCAAGGGAATCAACAAGGTGGCCATCAAG
GAAATCAACAAGGAACGGTTCCTACTCCGACTCAACCAAATAGTGAAGGAAACCACGAAAATTCTCGTGATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(511-579)

PASTA domain (PASTA)

(442-505)

PASTA domain (PASTA)

(371-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

77.778

91.837

0.714
  stkP Streptococcus pneumoniae D39

77.436

91.837

0.711
  stkP Streptococcus pneumoniae R6

77.436

91.837

0.711
  stkP Streptococcus pneumoniae Rx1

77.265

91.837

0.71
  pknB Streptococcus mutans UA159

55.959

90.895

0.509
  stkP/pknB Streptococcus salivarius strain HSISS4

54.223

92.936

0.504