Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   JJN14_RS04085 Genome accession   NZ_CP067992
Coordinates   824293..825033 (+) Length   246 a.a.
NCBI ID   WP_201059002.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V7-A3     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 819293..830033
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS04075 (JJN14_04075) - 820051..822642 (+) 2592 WP_201059000.1 MBL fold metallo-hydrolase -
  JJN14_RS04080 (JJN14_04080) - 822690..824168 (-) 1479 WP_201059001.1 oligosaccharide flippase family protein -
  JJN14_RS04085 (JJN14_04085) mecA 824293..825033 (+) 741 WP_201059002.1 adaptor protein MecA Regulator
  JJN14_RS04090 (JJN14_04090) - 825181..826467 (+) 1287 WP_201059003.1 homoserine dehydrogenase -
  JJN14_RS04095 (JJN14_04095) thrB 826469..827338 (+) 870 WP_201059004.1 homoserine kinase -
  JJN14_RS04100 (JJN14_04100) msrB 827437..828375 (+) 939 WP_201059005.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28536.34 Da        Isoelectric Point: 4.0236

>NTDB_id=526150 JJN14_RS04085 WP_201059002.1 824293..825033(+) (mecA) [Streptococcus mitis strain S022-V7-A3]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPESFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAENKKEPYIYYILSFA
KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMNHDAVLN
LQKIGS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=526150 JJN14_RS04085 WP_201059002.1 824293..825033(+) (mecA) [Streptococcus mitis strain S022-V7-A3]
ATGAAAATGAAACAAATTAGTGATACAACTTTGAAAATCACGATGTCTTTAGAGGATTTGATGGATCGTGGCATGGAGAT
TGCTGACTTTCTCGTTCCTCAAGAAAAAACAGAAGAGTTCTTTTATGCCATCTTGGATGAGTTAGAGATGCCTGAGAGCT
TTTTGGATACAGGTATGTTGAGCTTCCGTGTGACTCCAAAACCTGATAAGGTCGATGTCTTTGTGACCAAGTCAAAGATT
GACCAAAATCTAGATTTTGAAGACTTATCGGATTTGCCAGATATGGAAGAATTGGCTCAAATGTCGCCAGATGAGTTTAT
TAAAACCTTAGAAAAAAGCATCGCAGACAAAACCAAGGATGATATTGAAGCCATTCAATCTTTAGAGCAAGTTGAAGCCA
AGGAAGAAGAGCAGGAACAGGCTGAACAAGAAGCTGAAAACAAGAAAGAGCCTTACATCTACTACATCCTTTCTTTTGCT
AAGTTGGCTGACTTGGTTGCTTTTGCCAAGACAGTGACTTTTGAGATGGAAACTTCTGAACTCTACAAGATGAACGAGCG
CTATTATTTGACCATTTTAGTGGATATTGAAAATCATCCAAGTCCATATCCAGCATGGCTTTTGGCTCGTATGCGCGAGT
TTGCGGACGATAGTGACATCAGTCGCTCAGTTTTGCAAGAGTATGGTCAAGTCTTGATGAATCACGATGCAGTGCTTAAT
TTGCAAAAGATTGGTTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

98.367

99.593

0.98
  mecA Streptococcus pneumoniae D39

98.367

99.593

0.98
  mecA Streptococcus pneumoniae R6

98.367

99.593

0.98
  mecA Streptococcus pneumoniae TIGR4

97.959

99.593

0.976
  mecA Streptococcus mutans UA159

48.571

99.593

0.484
  mecA Streptococcus thermophilus LMD-9

47.39

100

0.48
  mecA Streptococcus thermophilus LMG 18311

46.988

100

0.476