Detailed information NTG0526121

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: JJN14_RS00220
• Genome accession: NZ_CP067992
• Coordinates: 40411..42564 (+)
• Length: 717 a.a.
• NCBI ID: WP_201058596.1
• Uniprot ID: -
• Organism: Streptococcus mitis strain S022-V7-A3
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	39269..39505	40411..42564	flank	906

Gene organization within MGE regions

Location: 39269..42564

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JJN14_RS10005	-	40060..40248 (+)	189	WP_236253696.1	hypothetical protein	-
JJN14_RS00220 (JJN14_00220)	comA	40411..42564 (+)	2154	WP_201058596.1	peptide cleavage/export ABC transporter ComA	Regulator

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80168.13 Da
• Isoelectric Point: 6.4561

>NTDB_id=526121 JJN14_RS00220 WP_201058596.1 40411..42564(+) (comA) [Streptococcus mitis strain S022-V7-A3]
MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
AFPFVAHVLKEGKLLHYYVVTGQDKDSIHIADPDPGVKLTKLSRERFAEEWTGVTLFMAPSPDYKPHKDQKNGLLSFIPI
LVKQRGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQKALKKVAHL
LLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFDEKKTVEDLSLM
KGDMTFKQVHYKYGYGRDVLSDINLTIPKGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILDNLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLSIAERTEKVVVLDQGKIVEEGNHADLLAQGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=526121 JJN14_RS00220 WP_201058596.1 40411..42564(+) (comA) [Streptococcus mitis strain S022-V7-A3]
ATGAAATTTGGGAAACGTCACTATCGTCCGCAGGTGGATCAGATGGACTGCGGTGTAGCTTCATTAGCCATGGTTTTTGG
CTACTATGGTAGTTATTATTCTTTGGCTCACTTGCGAGAATTGGCCAAGACAACCATGGATGGGACAACGGCTTTGGGCT
TGGTCAAGGTGGCAGAGGAAATTGGTTTTGAGACGCGAGCAATTAAGGCGGATATGACGCTCTTTGACTTGCCAGATTTG
GCTTTTCCTTTTGTTGCCCATGTGCTTAAGGAAGGGAAATTGCTCCACTACTATGTGGTGACTGGGCAGGATAAGGATAG
CATTCATATTGCCGATCCGGATCCTGGGGTGAAATTGACCAAACTGTCACGTGAGCGTTTTGCGGAAGAATGGACAGGAG
TGACTCTTTTTATGGCACCTAGTCCAGACTACAAGCCTCATAAGGATCAAAAGAATGGTCTGCTCTCTTTTATCCCTATA
TTAGTGAAGCAGCGTGGCTTGATTGCTAATATCGTTTTGGCAACACTCTTGGTAACCTTGATTAACATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACCTATGTGCCAGATCAGATGCGTTCGACGCTTGGGATTATTTCTATTGGGCTGGTTA
TCGTCTATATTCTCCAGCAAATCTTGTCTTACGCTCAGGAGTATCTCTTACTTGTTTTGGGGCAACGCTTGTCTATTGAT
GTGATTTTGTCCTATATCAAGCATGTTTTTCACCTGCCTATGTCCTTTTTTGCGACACGTCGTACAGGGGAAATCGTGTC
TCGTTTCACGGATGCTAACAGTATCATTGATGCGCTGGCTTCGACCATTCTTTCGATTTTCCTAGATGTATCAACGGTTG
TCATTATTTCCCTTGTTTTATTTTCACAAAATACCAATCTCTTTTTCATGACTTTATTGGCGCTCCCTATCTACACAGTG
ATTATCTTTGCCTTCATGAAGCCGTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATTGAGGACATCAATGGTATTGAAACTATCAAGTCCTTGACCAGTGAAAGTCAGCGTTACCAAAAGATTGACAAGGAAT
TTGTGGATTATCTGAAAAAATCCTTTACCTATAGTCGAGCAGAGAGTCAGCAAAAGGCTCTGAAAAAGGTTGCCCATCTC
TTGCTCAATGTCGGCATTCTCTGGATGGGGGCTGTTCTGGTCATGGATGGCAAGATGAGTTTGGGGCAGTTGATTACCTA
TAATACCTTGCTGGTTTACTTTACTAATCCTTTGGAGAATATCATCAACCTGCAAACTAAGCTTCAGACAGCGCAGGTTG
CCAATAACCGTCTAAATGAGGTTTATCTGGTAGCTTCTGAGTTTGATGAGAAGAAAACAGTTGAGGATCTGAGCTTGATG
AAGGGAGATATGACCTTCAAGCAGGTTCATTACAAGTATGGCTATGGTCGAGATGTCTTGTCAGATATCAATTTGACTAT
TCCCAAAGGCTCTAAGGTGGCTTTTGTGGGGATTTCGGGGTCAGGTAAGACGACCTTAGCTAAGATGATGGTTAATTTTT
ACGACCCAAGTCAAGGAGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAAGCCCTGCGCCAGTATATC
AACTATCTGCCTCAACAGCCCTATGTCTTTAATGGAACGATTTTGGACAATCTTCTCCTTGGAGCCAAGGAGGGGACGAC
ACAGGAAGATATCTTACGGGCGGTCGAATTGGCAGAGATTCGGGAGGATATCGAGCGTATGCCCCTGAATTACCAGACAG
AATTGACTTCGGATGGGGCAGGAATTTCAGGTGGTCAACGTCAGAGAATCGCTCTGGCGCGTGCTCTCTTGACAGATGCG
CCTGTCTTGATTTTGGATGAGGCGACCAGCAGTTTGGATATTTTGACAGAGAAGCGAATTGTAGATAATCTCATGGCTTT
AGATAAGACCTTGATTTTCATCGCCCACCGCTTGAGCATTGCTGAGCGGACAGAGAAGGTGGTTGTTTTGGATCAGGGCA
AGATTGTTGAAGAAGGAAATCATGCTGATTTACTTGCACAGGGTGGCTTTTACGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-650)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	98.884	100	0.989
comA	Streptococcus pneumoniae Rx1	98.187	100	0.982
comA	Streptococcus pneumoniae D39	98.187	100	0.982
comA	Streptococcus pneumoniae R6	98.187	100	0.982
comA	Streptococcus mitis SK321	98.047	100	0.98
comA	Streptococcus pneumoniae TIGR4	97.768	100	0.978
comA	Streptococcus gordonii str. Challis substr. CH1	80.614	100	0.806
comA/nlmT	Streptococcus mutans UA159	65.551	100	0.656