Detailed information NTG0052072

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SMUGS5_RS09805
• Genome accession: NC_018089
• Coordinates: 2024256..2025431 (+)
• Length: 391 a.a.
• NCBI ID: WP_014835077.1
• Uniprot ID: -
• Organism: Streptococcus mutans GS-5
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2019256..2030431

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUGS5_RS09795 (SMUGS5_09725)	-	2022534..2023196 (-)	663	WP_002262652.1	YoaK family protein	-
SMUGS5_RS09800 (SMUGS5_09730)	rlmH	2023539..2024018 (-)	480	WP_002262651.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SMUGS5_RS09805 (SMUGS5_09735)	htrA	2024256..2025431 (+)	1176	WP_014835077.1	S1C family serine protease	Regulator
SMUGS5_RS09810 (SMUGS5_09740)	-	2025898..2026667 (+)	770	Protein_1909	ParB/RepB/Spo0J family partition protein	-
SMUGS5_RS10300 (SMUGS5_09745)	-	2026869..2027027 (+)	159	Protein_1910	chromosomal replication initiator protein DnaA	-

Sequence

Protein

• Length: 391 a.a.
• Molecular weight: 41795.94 Da
• Isoelectric Point: 7.3047

>NTDB_id=52072 SMUGS5_RS09805 WP_014835077.1 2024256..2025431(+) (htrA) [Streptococcus mutans GS-5]
MVYTFFSYFLTFILGVISTLTFNWITGNKSFSNNGKTTVSNVIYDTKSNTTKAVKNVKNTVVSVINYQKTDNSYYNYDSG
SQEKNKSEDGLGVYGEGSGVIYKKDGDSAYLVTNNHVVKDAEKLEIMMANGKKVVGKLVGSDTYSDLAVIKISSKYVTTV
AEFANSDKIKVGEPAIAIGSPLGSDYANSVTEGIVSSLSRTVTSQNENGETISTNAIQTDAAINPGNSGGALINIKGQVI
GINSSKIASSNNSNSGVAVEGMGFAIPSNDVVSIINQLEENGEVVRPALGISMANLSEASTSGRDTLKIPSDVTSGIVVL
STQSGMPADGKLKKYDVITEIDGKKVASISDLQSILYKHKKGDKIKLTFYREKDKQTVEIQLTKTSQDLNH

Nucleotide

• Length: 1176 bp

>NTDB_id=52072 SMUGS5_RS09805 WP_014835077.1 2024256..2025431(+) (htrA) [Streptococcus mutans GS-5]
ATGGTTTATACCTTTTTTAGTTATTTTTTAACTTTTATTTTAGGGGTCATATCAACACTTACCTTTAATTGGATAACTGG
TAACAAATCGTTTTCTAACAATGGAAAAACAACTGTTAGTAATGTCATTTATGATACCAAATCTAACACTACCAAGGCTG
TTAAAAATGTCAAAAATACAGTTGTATCTGTCATCAATTATCAAAAAACAGATAATAGTTATTACAATTATGACAGCGGT
TCTCAAGAAAAAAATAAATCAGAGGATGGTCTAGGAGTCTACGGTGAAGGTTCTGGTGTTATCTATAAAAAAGATGGCGA
TAGTGCTTATTTAGTTACAAACAATCATGTCGTTAAAGATGCAGAAAAGTTAGAAATCATGATGGCTAATGGTAAAAAAG
TTGTCGGTAAATTAGTAGGTTCTGATACTTATTCTGATCTGGCTGTTATTAAAATTTCTTCTAAGTATGTTACGACAGTT
GCTGAATTTGCTAATTCGGATAAAATAAAAGTTGGAGAACCAGCAATCGCTATTGGTAGCCCTTTAGGCAGTGATTATGC
TAATTCTGTAACAGAAGGAATTGTTTCAAGTCTCAGTCGTACAGTAACTTCACAAAATGAAAATGGCGAAACAATTTCAA
CTAATGCTATTCAAACAGACGCAGCTATTAACCCTGGTAATTCTGGTGGCGCTTTAATTAATATCAAAGGACAAGTTATT
GGTATCAATTCAAGTAAAATTGCATCAAGTAATAACTCAAATAGTGGCGTTGCTGTTGAAGGAATGGGCTTTGCAATTCC
TTCAAACGATGTTGTCTCTATTATTAATCAATTAGAAGAAAATGGTGAAGTTGTTAGACCCGCTCTTGGTATTTCAATGG
CTAATCTTAGTGAAGCTTCAACAAGTGGAAGAGATACTTTAAAAATACCAAGTGATGTCACAAGCGGTATTGTTGTTCTT
TCAACACAAAGTGGTATGCCAGCAGATGGGAAGCTGAAGAAATATGATGTCATTACAGAAATTGATGGGAAGAAGGTAGC
GTCTATCAGCGATCTTCAAAGTATTCTTTACAAACACAAAAAGGGAGATAAAATTAAACTCACTTTCTATCGCGAAAAAG
ATAAACAAACAGTTGAGATCCAATTAACTAAAACAAGTCAAGATTTGAATCATTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (231-387)

• Trypsin-like peptidase domain (Trypsin_2) (97-242)

• PDZ domain (PDZ_2) (287-382)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	99.225	98.977	0.982
htrA	Streptococcus gordonii str. Challis substr. CH1	56.555	99.488	0.563
htrA	Streptococcus mitis NCTC 12261	55.352	97.954	0.542
htrA	Streptococcus pneumoniae Rx1	57.79	90.281	0.522
htrA	Streptococcus pneumoniae D39	57.79	90.281	0.522
htrA	Streptococcus pneumoniae R6	57.79	90.281	0.522
htrA	Streptococcus pneumoniae TIGR4	57.79	90.281	0.522