Detailed information NTG0052010

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SMUGS5_RS01235
• Genome accession: NC_018089
• Coordinates: 247400..249682 (+)
• Length: 760 a.a.
• NCBI ID: WP_014834813.1
• Uniprot ID: -
• Organism: Streptococcus mutans GS-5
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 242400..254682

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUGS5_RS01210 (SMUGS5_01105)	-	243187..243462 (+)	276	WP_042899546.1	hypothetical protein	-
SMUGS5_RS09930 (SMUGS5_01110)	-	243459..243635 (+)	177	WP_014834812.1	hypothetical protein	-
SMUGS5_RS09935 (SMUGS5_01115)	-	243676..243837 (+)	162	WP_162137339.1	hypothetical protein	-
SMUGS5_RS01215 (SMUGS5_01120)	-	244311..244520 (+)	210	WP_002273561.1	hypothetical protein	-
SMUGS5_RS01220 (SMUGS5_01125)	-	244756..245034 (+)	279	WP_002264456.1	hypothetical protein	-
SMUGS5_RS01225 (SMUGS5_01130)	-	246113..246313 (+)	201	WP_002294023.1	Blp family class II bacteriocin	-
SMUGS5_RS01230 (SMUGS5_01135)	-	246338..246745 (+)	408	WP_002266586.1	hypothetical protein	-
SMUGS5_RS01235 (SMUGS5_01145)	comA/nlmT	247400..249682 (+)	2283	WP_014834813.1	peptide cleavage/export ABC transporter	Regulator
SMUGS5_RS01240 (SMUGS5_01150)	comB/nlmE	249696..250598 (+)	903	WP_002263524.1	HlyD family efflux transporter periplasmic adaptor subunit	Regulator
SMUGS5_RS01245 (SMUGS5_01155)	-	250971..252638 (+)	1668	WP_002263525.1	BglG family transcription antiterminator	-
SMUGS5_RS01250 (SMUGS5_01160)	ulaG	253218..254309 (+)	1092	WP_002263526.1	L-ascorbate 6-phosphate lactonase	-

Sequence

Protein

• Length: 760 a.a.
• Molecular weight: 85120.85 Da
• Isoelectric Point: 8.9003

>NTDB_id=52010 SMUGS5_RS01235 WP_014834813.1 247400..249682(+) (comA/nlmT) [Streptococcus mutans GS-5]
MKQVIYVVLIVIAVNILLEVIKRVTKRGGTVSSSNPLPDGQSKLFWRRHYKLVPQIDTRDCGPAVLASVAKHYGSNYSIA
YLRELSKTNKQGTTALGIVEAAKKLGFETRSIKADMTLFDYNDLTYPFIVHVIKGKRLQHYYVVYGSQNNQLIIGDPDPS
VKVTRMSKERFQSEWTGLAIFLAPQPNYKPHKGEKNGLSNFFPLIFKQKALMTYIIIASLIVTLIDIVGSYYLQGILDEY
IPDQLISTLGMITIGLIITYIIQQVMAFAKEYLLAVLSLRLVIDVILSYIKHIFTLPMSFFATRRTGEITSRFTDANQII
DAVASTIFSIFLDMTMVILVGGVLLAQNNNLFFLTLLSIPIYAIIIFAFLKPFEKMNHEVMESNAVVSSSIIEDINGMET
IKSLTSESARYQNIDSEFVDYLEKNFKLHKYSAIQTALKSGAKLILNVVILWYGSRLVMDNKISVGQLITFNALLSYFSN
PIENIINLQSKLQSARVANTRLNEVYLVESEFEKDGDLSENSFLDGDISFENLSYKYGFGRDTLSDINLSIKKGSKVSLV
GASGSGKTTLAKLIVNFYEPNKGIVRINGNDLKVIDKTALRRYISYLPQQAYVFSGSIMDNLVLGAKEGTSQEDIIRACE
IAEIRSDIEQMPQGYQTELSDGAGISGGQKQRIALARALLTQAPVLILDEATSSLDILIEKKIISNLLQMTEKTIIFVAH
RLSISQRTDEVIVMDQGKIVEQGTHKELLAKQGFYYNLFN

Nucleotide

• Length: 2283 bp

>NTDB_id=52010 SMUGS5_RS01235 WP_014834813.1 247400..249682(+) (comA/nlmT) [Streptococcus mutans GS-5]
ATGAAACAAGTTATTTATGTTGTTTTAATCGTCATAGCCGTTAACATTCTCTTAGAGGTTATCAAAAGAGTAACAAAAAG
GGGAGGGACAGTTTCGTCATCTAATCCTTTACCAGATGGGCAGTCTAAGTTGTTTTGGCGCAGACATTATAAGCTAGTAC
CTCAGATTGATACCAGAGACTGTGGGCCGGCAGTGCTGGCATCTGTTGCAAAGCATTACGGATCTAACTACTCTATCGCT
TATCTGCGGGAACTCTCAAAGACTAACAAGCAGGGAACAACAGCTCTTGGCATTGTTGAAGCTGCTAAAAAGTTAGGCTT
TGAAACACGCTCTATCAAGGCGGATATGACGCTTTTTGATTATAATGATTTGACCTATCCTTTTATCGTCCATGTGATTA
AAGGAAAACGTCTGCAGCATTATTATGTCGTCTATGGCAGCCAGAATAATCAGCTGATTATTGGAGATCCTGATCCTTCA
GTTAAGGTGACTAGGATGAGTAAGGAACGCTTTCAATCAGAGTGGACAGGCCTTGCAATTTTCCTAGCTCCTCAGCCTAA
CTATAAGCCTCATAAAGGTGAAAAAAATGGTTTGTCTAATTTCTTCCCGTTGATCTTTAAGCAGAAAGCTTTGATGACTT
ATATTATCATAGCTAGCTTGATTGTGACGCTCATTGATATTGTCGGATCATACTATCTCCAAGGAATATTGGACGAGTAC
ATTCCTGATCAGCTGATTTCAACTTTAGGAATGATTACGATTGGTCTGATAATAACCTATATTATCCAGCAGGTCATGGC
TTTTGCAAAAGAATACCTCTTGGCCGTACTCAGTTTGCGTTTAGTCATTGATGTTATCCTGTCTTATATCAAACATATTT
TTACGCTTCCTATGTCTTTCTTTGCGACAAGGCGAACAGGAGAAATCACGTCTCGTTTTACAGATGCCAATCAGATTATT
GATGCTGTAGCGTCAACCATCTTTTCAATCTTTTTAGATATGACTATGGTGATTTTGGTTGGCGGGGTTTTGTTGGCGCA
AAACAATAACCTTTTCTTTCTAACCTTGCTCTCCATTCCGATTTATGCCATCATTATTTTTGCTTTCTTGAAACCCTTTG
AGAAAATGAATCACGAAGTGATGGAAAGCAATGCTGTGGTAAGTTCTTCTATCATTGAAGATATCAATGGGATGGAAACC
ATTAAATCACTCACAAGTGAGTCCGCTCGTTATCAAAACATTGATAGTGAATTTGTTGATTATTTGGAGAAAAACTTTAA
GCTACACAAGTATAGTGCCATTCAAACCGCATTAAAAAGCGGTGCTAAGCTTATCCTCAATGTTGTCATTCTCTGGTATG
GCTCTCGTCTAGTTATGGATAATAAAATCTCAGTTGGTCAGCTTATCACCTTTAATGCTTTGCTGTCTTATTTCTCAAAT
CCAATTGAAAATATTATCAATCTGCAATCCAAACTGCAGTCAGCTCGCGTTGCCAATACACGTCTTAATGAAGTCTATCT
TGTCGAATCTGAATTTGAAAAAGACGGTGATTTATCAGAAAATAGCTTTTTAGATGGTGATATTTCGTTTGAAAATCTTT
CTTATAAATATGGATTTGGGCGAGATACCTTATCAGATATTAATTTATCAATCAAAAAAGGCTCCAAGGTCAGTCTAGTT
GGAGCCAGTGGTTCTGGTAAGACAACTTTGGCTAAACTGATTGTCAATTTCTACGAGCCTAACAAGGGGATTGTTCGAAT
CAATGGCAATGATTTAAAAGTTATTGATAAGACAGCTTTGCGGCGGTATATTAGCTATTTGCCGCAACAGGCCTATGTTT
TTAGTGGCTCTATTATGGATAATCTCGTTTTAGGAGCTAAAGAAGGAACGAGTCAGGAAGACATTATTCGTGCTTGTGAA
ATTGCTGAAATCCGCTCGGACATTGAACAAATGCCTCAAGGCTATCAGACAGAGTTATCAGATGGTGCCGGTATTTCTGG
CGGTCAAAAACAGCGGATTGCTTTAGCTAGGGCCTTATTAACACAGGCACCGGTTTTGATTCTGGATGAAGCCACCAGCA
GTCTTGATATTTTGATAGAAAAGAAAATTATCAGCAATCTCTTACAGATGACGGAGAAAACAATAATTTTTGTTGCCCAC
CGCTTAAGCATTTCACAGCGTACTGACGAAGTCATTGTCATGGATCAAGGAAAAATTGTTGAACAAGGCACTCATAAGGA
ACTTTTAGCTAAGCAAGGTTTCTATTATAACCTGTTTAATTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (50-186)

• ABC transporter transmembrane region (ABC_membrane) (212-481)

• ABC transporter (ABC_tran) (544-693)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	99.605	100	0.996
comA	Streptococcus mitis NCTC 12261	65.411	94.342	0.617
comA	Streptococcus pneumoniae Rx1	64.854	94.342	0.612
comA	Streptococcus pneumoniae D39	64.854	94.342	0.612
comA	Streptococcus pneumoniae R6	64.854	94.342	0.612
comA	Streptococcus mitis SK321	64.714	94.342	0.611
comA	Streptococcus pneumoniae TIGR4	64.575	94.342	0.609
comA	Streptococcus gordonii str. Challis substr. CH1	64.435	94.342	0.608