Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   K0V03_RS10140 Genome accession   NZ_CP080508
Coordinates   1913974..1915176 (-) Length   400 a.a.
NCBI ID   WP_015250812.1    Uniprot ID   A0ABU0V6N7
Organism   Bacillus subtilis strain HD15     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1908974..1920176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K0V03_RS10110 (K0V03_10110) rocD 1909649..1910854 (-) 1206 WP_069838313.1 ornithine aminotransferase -
  K0V03_RS10115 (K0V03_10115) - 1911130..1911762 (-) 633 WP_085185985.1 SdpI family protein -
  K0V03_RS10120 (K0V03_10120) - 1911762..1912046 (-) 285 WP_015715052.1 autorepressor SdpR family transcription factor -
  K0V03_RS10125 (K0V03_10125) rocR 1912276..1913661 (+) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  K0V03_RS10130 (K0V03_10130) - 1913643..1913795 (-) 153 Protein_2009 ATP-binding protein -
  K0V03_RS10135 (K0V03_10135) - 1913823..1913953 (-) 131 Protein_2010 hypothetical protein -
  K0V03_RS10140 (K0V03_10140) htrA 1913974..1915176 (-) 1203 WP_015250812.1 serine protease HtrC Regulator
  K0V03_RS10145 (K0V03_10145) vicX 1915258..1916052 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  K0V03_RS10150 (K0V03_10150) walI 1916074..1916916 (-) 843 WP_046161072.1 WalRK two-component regulatory system regulator WalI -
  K0V03_RS10155 (K0V03_10155) walH 1916903..1918270 (-) 1368 WP_046664054.1 WalRK two-component regulatory system regulator WalH -
  K0V03_RS10160 (K0V03_10160) walK 1918260..1920095 (-) 1836 WP_024572714.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42756.50 Da        Isoelectric Point: 5.5340

>NTDB_id=520020 K0V03_RS10140 WP_015250812.1 1913974..1915176(-) (htrA) [Bacillus subtilis strain HD15]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNTVTK
IVSNVSPAVVGVVNIQKSDIRGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=520020 K0V03_RS10140 WP_015250812.1 1913974..1915176(-) (htrA) [Bacillus subtilis strain HD15]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGTAAAAAAGGATATTTTCTTTCTAG
CCTGATTGGTGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTATCTTTCAAATGAAGGGCTAGATACGGGCG
CTTTAGATCAGCAGCAGAACAATAACGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATACGGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATACGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGATCGCGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGATCTG
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCAGCGGT
TGAAGGGATTGGCCTGTCCATTCCGTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGACTGAAGGAACTCGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTTGACATCAAGCTGTCGTCCGCAGACCAATTAGGAAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(196-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378