NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	KZ312_RS24350	Genome accession	NZ_CP080260
Coordinates	5076964..5078088 (-)	Length	374 a.a.
NCBI ID	WP_059328121.1	Uniprot ID	-
Organism	Escherichia coli strain 135
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 5071964..5083088

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KZ312_RS24320 (KZ312_24320)	yrdA	5073764..5074318 (+)	555	WP_001286217.1	gamma carbonic anhydrase family protein	-
KZ312_RS24325 (KZ312_24325)	yrdB	5074294..5074551 (-)	258	WP_059328123.1	DUF1488 domain-containing protein	-
KZ312_RS24330 (KZ312_24330)	aroE	5074548..5075366 (-)	819	WP_059328122.1	shikimate dehydrogenase	-
KZ312_RS24335 (KZ312_24335)	tsaC	5075371..5075943 (-)	573	WP_001297709.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
KZ312_RS24340 (KZ312_24340)	yrdD	5075948..5076490 (-)	543	WP_001129723.1	type I DNA topoisomerase	-
KZ312_RS24345 (KZ312_24345)	smg	5076519..5076992 (-)	474	WP_000460672.1	DUF494 family protein Smg	-
KZ312_RS24350 (KZ312_24350)	dprA	5076964..5078088 (-)	1125	WP_059328121.1	DNA-protecting protein DprA	Machinery gene
KZ312_RS24355 (KZ312_24355)	def	5078218..5078727 (+)	510	WP_000114986.1	peptide deformylase	-
KZ312_RS24360 (KZ312_24360)	fmt	5078742..5079689 (+)	948	WP_000004456.1	methionyl-tRNA formyltransferase	-
KZ312_RS24365 (KZ312_24365)	rsmB	5079735..5081024 (+)	1290	WP_059328120.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
KZ312_RS24370 (KZ312_24370)	trkA	5081046..5082422 (+)	1377	WP_219790118.1	Trk system potassium transporter TrkA	-
KZ312_RS24375 (KZ312_24375)	mscL	5082552..5082962 (+)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40991.96 Da Isoelectric Point: 6.5011

                                >NTDB_id=518908 KZ312_RS24350 WP_059328121.1 5076964..5078088(-) (dprA) [Escherichia coli strain 135]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLSWLKQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=518908 KZ312_RS24350 WP_059328121.1 5076964..5078088(-) (dprA) [Escherichia coli strain 135]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTCTTGGTTGAAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT

TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	48.71	82.888	0.404
dprA	Vibrio cholerae strain A1552	48.71	82.888	0.404
dprA	Glaesserella parasuis strain SC1401	44.51	90.107	0.401
dprA	Haemophilus influenzae Rd KW20	43.917	90.107	0.396
dprA	Legionella pneumophila strain ERS1305867	43.363	90.642	0.393

Detailed information NTG0518908