Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   SCIM_RS02285 Genome accession   NC_018073
Coordinates   456993..457676 (-) Length   227 a.a.
NCBI ID   WP_003073610.1    Uniprot ID   A0AAE8KBD8
Organism   Streptococcus intermedius JTH08     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 451993..462676
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCIM_RS02255 (SCIM_0395) rsmD 452474..453013 (+) 540 WP_003078233.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SCIM_RS02260 (SCIM_0396) coaD 453003..453500 (+) 498 WP_003078294.1 pantetheine-phosphate adenylyltransferase -
  SCIM_RS02265 (SCIM_0397) sepM 453481..454536 (+) 1056 WP_003078259.1 SepM family pheromone-processing serine protease Regulator
  SCIM_RS02270 (SCIM_0398) - 454817..455380 (+) 564 WP_004234076.1 YutD family protein -
  SCIM_RS02275 (SCIM_0399) rlmN 455414..456496 (+) 1083 WP_003078352.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  SCIM_RS02280 (SCIM_0400) - 456489..457007 (+) 519 WP_003078328.1 VanZ family protein -
  SCIM_RS02285 (SCIM_0401) cclA/cilC 456993..457676 (-) 684 WP_003073610.1 prepilin peptidase Machinery gene
  SCIM_RS02290 (SCIM_0402) - 457827..458354 (+) 528 WP_003078413.1 Dps family protein -
  SCIM_RS02295 - 458617..458841 (+) 225 WP_003073604.1 YqgQ family protein -
  SCIM_RS02300 (SCIM_0403) - 458835..459215 (+) 381 WP_003078427.1 rhodanese-like domain-containing protein -
  SCIM_RS02305 (SCIM_0404) - 459236..459961 (-) 726 WP_004234062.1 16S rRNA pseudouridine(516) synthase -
  SCIM_RS02310 (SCIM_0405) typA 460142..461983 (+) 1842 WP_003078415.1 translational GTPase TypA -
  SCIM_RS02315 (SCIM_0406) - 462045..462329 (+) 285 WP_003073594.1 DUF3165 family protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 25602.95 Da        Isoelectric Point: 8.2377

>NTDB_id=51859 SCIM_RS02285 WP_003073610.1 456993..457676(-) (cclA/cilC) [Streptococcus intermedius JTH08]
MVHFYFFLVGSIVASFLGLVVDRFPEQSIIVPSSHCNTCGQKLTPRDLVPILSQLINRLRCRFCGEKIPIRYILLELTGG
CLFLVTSLGYLNINQLILLVSGMTLSLYDQRHQEYPLLIWLFSHVLLLFLTGFNLLMAIFLALGILTHFIDLRIGAGDFL
FLASCSAIFNLTEVLLVLQISSIIGLFLFCLKSRKDRLAFIPCLFGASSILILIKFVVFHQNILCLI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=51859 SCIM_RS02285 WP_003073610.1 456993..457676(-) (cclA/cilC) [Streptococcus intermedius JTH08]
ATGGTTCATTTTTATTTTTTCTTAGTTGGAAGTATTGTGGCTTCCTTTTTAGGCCTGGTCGTTGATCGCTTTCCTGAACA
ATCTATTATCGTTCCTTCCAGTCATTGCAATACTTGTGGACAAAAATTAACTCCACGTGATTTAGTCCCTATCCTCTCAC
AACTCATCAATCGTCTACGTTGTCGCTTTTGTGGTGAAAAAATTCCCATCCGCTACATTCTCCTAGAACTAACTGGTGGT
TGTCTCTTTCTTGTAACGTCTTTAGGCTATCTAAACATCAACCAGCTCATCCTGCTTGTATCTGGGATGACCTTATCCCT
TTATGATCAGAGACATCAAGAGTATCCTCTGCTTATTTGGCTATTTTCCCATGTCCTTCTTCTCTTTTTAACTGGTTTCA
ATCTTTTGATGGCTATTTTTTTAGCCCTTGGAATTTTAACTCATTTCATTGATTTGCGCATTGGAGCGGGAGATTTTCTT
TTTCTAGCATCCTGTTCAGCGATTTTTAATCTCACAGAAGTTCTCCTTGTTCTTCAAATTTCCAGCATCATCGGCCTGTT
CCTTTTTTGTTTAAAGTCAAGAAAAGACAGATTAGCATTTATTCCCTGTCTTTTTGGTGCTAGCAGCATTCTGATTTTGA
TAAAATTCGTTGTTTTCCACCAAAATATTTTATGCCTTATTTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-87)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

56.279

94.714

0.533
  cclA/cilC Streptococcus mitis NCTC 12261

55.349

94.714

0.524
  cclA/cilC Streptococcus pneumoniae Rx1

54.884

94.714

0.52
  cclA/cilC Streptococcus pneumoniae D39

54.884

94.714

0.52
  cclA/cilC Streptococcus pneumoniae R6

54.884

94.714

0.52
  cclA/cilC Streptococcus pneumoniae TIGR4

54.419

94.714

0.515

Multiple sequence alignment