Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   JDY60_RS02325 Genome accession   NZ_CP066172
Coordinates   495273..496013 (+) Length   246 a.a.
NCBI ID   WP_200371615.1    Uniprot ID   -
Organism   Streptococcus oralis strain SF100     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 490273..501013
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JDY60_RS02315 (JDY60_02315) - 491113..493626 (+) 2514 WP_200371226.1 MBL fold metallo-hydrolase -
  JDY60_RS02320 (JDY60_02320) - 493672..495150 (-) 1479 WP_000789703.1 oligosaccharide flippase family protein -
  JDY60_RS02325 (JDY60_02325) mecA 495273..496013 (+) 741 WP_200371615.1 adaptor protein MecA Regulator
  JDY60_RS02330 (JDY60_02330) - 496161..497447 (+) 1287 WP_200371228.1 homoserine dehydrogenase -
  JDY60_RS02335 (JDY60_02335) thrB 497449..498318 (+) 870 WP_044020572.1 homoserine kinase -
  JDY60_RS02340 (JDY60_02340) msrB 498532..499470 (+) 939 WP_200371229.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28597.37 Da        Isoelectric Point: 4.1097

>NTDB_id=518037 JDY60_RS02325 WP_200371615.1 495273..496013(+) (mecA) [Streptococcus oralis strain SF100]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQADKETENKKEPYIYYILRFS
SLADLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLN
LQKIRS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=518037 JDY60_RS02325 WP_200371615.1 495273..496013(+) (mecA) [Streptococcus oralis strain SF100]
ATGAAGATGAAACAAATCAGTGATACAACACTAAAAATCACGATGACTTTAGATGATTTGATGGACCGAGGAATGGAGAT
TGCAGACTTTCTCGTTCCTCAGGAAAAAACCGAAGAGTTTTTCTATGCTATTTTAGATGAGTTAGAGATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTCCGCGTGACGCCAAAACCTGATAAGGTGGACGTCTTTGTGACCAAGTCCAAGATT
GACCAGAATTTGGATTTTGAAGATTTGGCGGATCTACCAGACATGGAAGAATTAGCCCAAATGTCGCCGGATGAATTTCT
CAAAACCTTGGAAAAGAGTATTGCAGATAAGACCAAGGACGATATTGAGGCCATCCAATCTCTAGAGCAGGTCGAAGCAA
AGGAAGAAGAGCAAGAGCAGGCAGACAAGGAGACTGAGAATAAGAAAGAACCTTATATCTACTATATCCTGCGCTTTTCA
AGCCTTGCTGACTTGGTTGCTTTTGCAAAGACGGTTAACTACCAGATGGAAACATCTGAACTCTATAAGATGAATGGGCA
CTACTATTTGACAATCTTAGTCGATGTGGAAAATCATCCAAGTCCATATCCGGCTTGGCTCTTGGCTCGTATGCGTGAGT
TTGCAGACGACAGTGACATCAGTCGTTCAGTCTTGCAAGAGTATGGGCAAATCTTGATCAATCACGATGCAGTTCTTAAT
CTGCAAAAGATTCGTTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.574

99.187

0.898
  mecA Streptococcus pneumoniae D39

90.574

99.187

0.898
  mecA Streptococcus pneumoniae R6

90.574

99.187

0.898
  mecA Streptococcus pneumoniae TIGR4

90.164

99.187

0.894
  mecA Streptococcus thermophilus LMD-9

48.016

100

0.492
  mecA Streptococcus thermophilus LMG 18311

47.619

100

0.488
  mecA Streptococcus mutans UA159

48.361

99.187

0.48