Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   I6I02_RS10400 Genome accession   NZ_CP066093
Coordinates   2230646..2231881 (-) Length   411 a.a.
NCBI ID   WP_002892211.1    Uniprot ID   J7SI15
Organism   Streptococcus salivarius strain FDAARGOS_1045     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2225646..2236881
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I02_RS10380 (I6I02_10380) - 2226676..2226867 (-) 192 WP_037599384.1 DUF951 domain-containing protein -
  I6I02_RS10385 (I6I02_10385) dnaN 2226919..2228055 (-) 1137 WP_110980770.1 DNA polymerase III subunit beta -
  I6I02_RS10390 (I6I02_10390) dnaA 2228211..2229575 (-) 1365 WP_037599382.1 chromosomal replication initiator protein DnaA -
  I6I02_RS10395 (I6I02_10395) spo0J 2229813..2230580 (-) 768 WP_037598566.1 ParB/RepB/Spo0J family partition protein Regulator
  I6I02_RS10400 (I6I02_10400) htrA 2230646..2231881 (-) 1236 WP_002892211.1 S1C family serine protease Regulator
  I6I02_RS10405 (I6I02_10405) rlmH 2232087..2232566 (+) 480 WP_037598563.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6I02_RS10410 (I6I02_10410) - 2232583..2233266 (+) 684 WP_002892206.1 YoaK family protein -
  I6I02_RS10430 (I6I02_10430) - 2233816..2236410 (-) 2595 WP_198463569.1 YfhO family protein -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 42959.14 Da        Isoelectric Point: 4.6304

>NTDB_id=517394 I6I02_RS10400 WP_002892211.1 2230646..2231881(-) (htrA) [Streptococcus salivarius strain FDAARGOS_1045]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYNNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSSQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=517394 I6I02_RS10400 WP_002892211.1 2230646..2231881(-) (htrA) [Streptococcus salivarius strain FDAARGOS_1045]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCAATTGCAATGCTTGTTATTGGCTTACTAGGTGGTCTACTAGGTGC
CTTTATCCTATTAACAGCAGCAGGGGTATCTTTTACCAATACAACAGATACAGGTGTTAAAACAGCTAAGACCGTATACA
ACAATACAACAGATACAACTAAGGCCGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTACCAAGAAGGCTCA
TCTTCAGATTCCCTAAATGAACTTTATGGTCGTATTTTTGGTGGAGATGATAGTTCTGATTCTAGCCAAGACAAATCAAA
AGATTCTGATGGATTGCAAGTCGCTGGTGAAGGTTCCGGTGTTATCTATAAAAAAGATGGGAAAGAGGCCTACATCGTAA
CCAACAACCACGTTGTTGATGGTGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTCGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATAAAAACCGTCGCAGAATTTGCAGATTC
AAACTCCCTCACAGTTGGTGAAAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAGG
GAATCGTATCTAGCCTTAGCCGTACCGTAACTATGCAAAACGACAATGGTGAAACTGTCTCAACAAATGCTATCCAAACA
GATGCTGCCATTAACCCTGGTAACTCTGGTGGTGCCTTAGTCAATATTGAAGGACAAGTTATCGGTATTAACTCAAGTAA
GATTTCATCAACGTCAGCAGTCGCTGGTAGTGCCGTTGAAGGTATGGGATTCGCCATTCCATCAAACGATGTTGTCGAAA
TCATTAATCAATTGGAAAAAGACGGTAAAGTTACACGCCCAGCCCTAGGAATCTCAATGGCCGATCTTAATAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGAAGTTAAATCTGGAGTTGTTGTCGGTAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATTACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTATCTGACTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(118-263)

Peptidase family M50 (Peptidase_M50)

(4-406)

PDZ domain (PDZ_2)

(307-402)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SI15

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.787

98.054

0.606
  htrA Streptococcus gordonii str. Challis substr. CH1

57.524

100

0.577
  htrA Streptococcus mitis NCTC 12261

54.768

99.513

0.545
  htrA Streptococcus pneumoniae TIGR4

54.523

99.513

0.543
  htrA Streptococcus pneumoniae D39

54.523

99.513

0.543
  htrA Streptococcus pneumoniae Rx1

54.523

99.513

0.543
  htrA Streptococcus pneumoniae R6

54.523

99.513

0.543