Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   I6I02_RS09410 Genome accession   NZ_CP066093
Coordinates   2051930..2052679 (-) Length   249 a.a.
NCBI ID   WP_198463518.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_1045     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2046930..2057679
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I02_RS09390 (I6I02_09390) - 2047252..2048484 (-) 1233 WP_198463517.1 cysteine desulfurase -
  I6I02_RS09395 (I6I02_09395) sufD 2048538..2049800 (-) 1263 WP_048790376.1 Fe-S cluster assembly protein SufD -
  I6I02_RS09400 (I6I02_09400) sufC 2049837..2050607 (-) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  I6I02_RS09405 (I6I02_09405) - 2050769..2051926 (-) 1158 WP_002889771.1 glycosyltransferase family 4 protein -
  I6I02_RS09410 (I6I02_09410) mecA 2051930..2052679 (-) 750 WP_198463518.1 adaptor protein MecA Regulator
  I6I02_RS09415 (I6I02_09415) - 2052886..2053257 (+) 372 WP_198463519.1 DUF3021 family protein -
  I6I02_RS09420 (I6I02_09420) - 2053317..2054171 (-) 855 WP_002883622.1 undecaprenyl-diphosphate phosphatase -
  I6I02_RS09425 (I6I02_09425) - 2054377..2055924 (+) 1548 WP_037597348.1 ABC transporter substrate-binding protein/permease -
  I6I02_RS09430 (I6I02_09430) - 2055924..2056664 (+) 741 WP_002886432.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29100.68 Da        Isoelectric Point: 4.0217

>NTDB_id=517387 I6I02_RS09410 WP_198463518.1 2051930..2052679(-) (mecA) [Streptococcus salivarius strain FDAARGOS_1045]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEELDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEENIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=517387 I6I02_RS09410 WP_198463518.1 2051930..2052679(-) (mecA) [Streptococcus salivarius strain FDAARGOS_1045]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTACACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGCGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGACCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGAACTTGATTTCAACGATTTGTCAGATATGGACGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTCAAGGCTCT
TGAAGGTAACTTTATGGACAAGGGGGATATCGAAGCACACCATAAGCTCGAAGAACTTGAGAAGACCTTGGAAGAAGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGGCTGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTACACAAGGGCTGAAAGATGTGCCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GGATGTCTACTATATGACAATCCTTCTTTACTTAGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTGCCTACCTGCAAGAGCATGCAACAATTTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.976

100

0.94
  mecA Streptococcus thermophilus LMG 18311

93.574

100

0.936
  mecA Streptococcus mutans UA159

60.246

97.992

0.59
  mecA Streptococcus pneumoniae Rx1

47.39

100

0.474
  mecA Streptococcus pneumoniae D39

47.39

100

0.474
  mecA Streptococcus pneumoniae R6

47.39

100

0.474
  mecA Streptococcus pneumoniae TIGR4

47.39

100

0.474