Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6I02_RS08845 Genome accession   NZ_CP066093
Coordinates   1937945..1938634 (-) Length   229 a.a.
NCBI ID   WP_002883757.1    Uniprot ID   A0AB33ZE44
Organism   Streptococcus salivarius strain FDAARGOS_1045     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1932945..1943634
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I02_RS08825 (I6I02_08825) dnaI 1933740..1934642 (-) 903 WP_002883792.1 primosomal protein DnaI -
  I6I02_RS08830 (I6I02_08830) - 1934646..1935821 (-) 1176 WP_198463479.1 DnaD domain protein -
  I6I02_RS08835 (I6I02_08835) nrdR 1935818..1936297 (-) 480 WP_198463480.1 transcriptional regulator NrdR -
  I6I02_RS08840 (I6I02_08840) covS 1936419..1937948 (-) 1530 WP_002889963.1 HAMP domain-containing histidine kinase Regulator
  I6I02_RS08845 (I6I02_08845) covR 1937945..1938634 (-) 690 WP_002883757.1 response regulator transcription factor Regulator
  I6I02_RS08850 (I6I02_08850) - 1938790..1939326 (-) 537 WP_198463481.1 DUF177 domain-containing protein -
  I6I02_RS08855 (I6I02_08855) rsmG 1939625..1940338 (+) 714 WP_048673867.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  I6I02_RS08860 (I6I02_08860) - 1940407..1941771 (+) 1365 WP_269780036.1 TrkH family potassium uptake protein -
  I6I02_RS08865 (I6I02_08865) - 1941811..1942482 (+) 672 WP_104020636.1 potassium channel family protein -
  I6I02_RS08870 (I6I02_08870) - 1942571..1943401 (-) 831 WP_198463482.1 energy-coupling factor transporter transmembrane component T family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26501.51 Da        Isoelectric Point: 4.6354

>NTDB_id=517380 I6I02_RS08845 WP_002883757.1 1937945..1938634(-) (covR) [Streptococcus salivarius strain FDAARGOS_1045]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=517380 I6I02_RS08845 WP_002883757.1 1937945..1938634(-) (covR) [Streptococcus salivarius strain FDAARGOS_1045]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGTGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCCCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGTGGTGCTGATGACTATATTGTAAAACCTTTTGCGATTGA
AGAACTATTGGCACGTATTCGTGCAACCTTCCGTCGCCAAGATATCGAAGCTGCTAAGAATGCACCAGCTAAAGCGTCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGATGCAATCGAAACAAACGTTGTAGACGTTTATATTCGTTACTTGCGTGGAAAAATCGATGTTCCAGGTAAGGAAT
CATACATTCAAACAGTGCGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

100

100

1
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

45.923

100

0.467
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445