Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   I6I02_RS08840 Genome accession   NZ_CP066093
Coordinates   1936419..1937948 (-) Length   509 a.a.
NCBI ID   WP_002889963.1    Uniprot ID   J7SI89
Organism   Streptococcus salivarius strain FDAARGOS_1045     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1931419..1942948
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I02_RS08815 (I6I02_08815) - 1931630..1932259 (-) 630 WP_198463478.1 ribonuclease P -
  I6I02_RS08820 (I6I02_08820) der 1932324..1933634 (-) 1311 WP_037597430.1 ribosome biogenesis GTPase Der -
  I6I02_RS08825 (I6I02_08825) dnaI 1933740..1934642 (-) 903 WP_002883792.1 primosomal protein DnaI -
  I6I02_RS08830 (I6I02_08830) - 1934646..1935821 (-) 1176 WP_198463479.1 DnaD domain protein -
  I6I02_RS08835 (I6I02_08835) nrdR 1935818..1936297 (-) 480 WP_198463480.1 transcriptional regulator NrdR -
  I6I02_RS08840 (I6I02_08840) covS 1936419..1937948 (-) 1530 WP_002889963.1 HAMP domain-containing histidine kinase Regulator
  I6I02_RS08845 (I6I02_08845) covR 1937945..1938634 (-) 690 WP_002883757.1 response regulator transcription factor Regulator
  I6I02_RS08850 (I6I02_08850) - 1938790..1939326 (-) 537 WP_198463481.1 DUF177 domain-containing protein -
  I6I02_RS08855 (I6I02_08855) rsmG 1939625..1940338 (+) 714 WP_048673867.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  I6I02_RS08860 (I6I02_08860) - 1940407..1941771 (+) 1365 WP_269780036.1 TrkH family potassium uptake protein -
  I6I02_RS08865 (I6I02_08865) - 1941811..1942482 (+) 672 WP_104020636.1 potassium channel family protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58068.44 Da        Isoelectric Point: 5.1853

>NTDB_id=517379 I6I02_RS08840 WP_002889963.1 1936419..1937948(-) (covS) [Streptococcus salivarius strain FDAARGOS_1045]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLFSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=517379 I6I02_RS08840 WP_002889963.1 1936419..1937948(-) (covS) [Streptococcus salivarius strain FDAARGOS_1045]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTGTTTTCTCGGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAA
ATAACACAATTTCGAAAGTTGTTACTTATATCGAAAAGGACTGGGATTCTGATGAAGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCGCCTAAAAATATCTATGCATCAATCATTAATGGTGTGCTTTCTGAAAAGCACTCTTTGGATGGTCA
AGTTGCAATTTCTAATAAATTATTTTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAAAACACAGACTCTCCTCCAGGCATGTCTGAAGTAAACAAACTGAAGTCAGTGTCCTATAAAGGAAAGCGTGGTTTC
TTACTACAAGTTCCAATTTACGGTAAGGATAAAAAGACCATCGTTGGTTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTGAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTCCTAGTTATCGCAGCAACTG
TGGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTTAGTCATGAATTACGTACGCCGATTGCGGTTATCAAGG
GCCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAGGAGAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCATAGAAATGA
TACGTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCATGAAGATTACCAATTCTATCTCA
ATGATTTTGAGAGCTCAGAGCGTCCAGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACTATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTACAAGTACA
AGATAATGGCGAAGGGATTTCTAAAGAAGATATTGAGCATATCTTTGAACGCTTCTATCGTTCAGATAAGGCACGTAATC
GTACGACAACACAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTACCAAATTGTGGAAGCTTATCGCTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCGGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SI89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

99.607

100

0.996