Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   I6I02_RS02355 Genome accession   NZ_CP066093
Coordinates   475422..477296 (+) Length   624 a.a.
NCBI ID   WP_073685669.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_1045     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 470422..482296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I02_RS02340 (I6I02_02340) fmt 472394..473329 (+) 936 WP_073685671.1 methionyl-tRNA formyltransferase -
  I6I02_RS02345 (I6I02_02345) rsmB 473319..474641 (+) 1323 WP_073685670.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  I6I02_RS02350 (I6I02_02350) - 474685..475422 (+) 738 WP_198463716.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  I6I02_RS02355 (I6I02_02355) stkP/pknB 475422..477296 (+) 1875 WP_073685669.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  I6I02_RS02360 (I6I02_02360) - 477442..478200 (+) 759 WP_198463717.1 potassium channel family protein -
  I6I02_RS02365 (I6I02_02365) liaF 478363..479061 (+) 699 WP_073685667.1 cell wall-active antibiotics response protein LiaF -
  I6I02_RS02370 (I6I02_02370) - 479058..480068 (+) 1011 WP_002891418.1 sensor histidine kinase -
  I6I02_RS02375 (I6I02_02375) - 480058..480702 (+) 645 WP_002891417.1 response regulator transcription factor -
  I6I02_RS02390 (I6I02_02390) rimM 481398..481916 (+) 519 WP_060971504.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67978.80 Da        Isoelectric Point: 6.7045

>NTDB_id=517350 I6I02_RS02355 WP_073685669.1 475422..477296(+) (stkP/pknB) [Streptococcus salivarius strain FDAARGOS_1045]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNEKVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSIAQTKIEGAGFKVGEVKEV
EDDSVDTGKVIKTDPIAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGE
ILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKNISSSSIEYHDYNTGAKLDKDKIPSSTEV
LYQDPQAGTSVDGTVILYVSVATASSNLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=517350 I6I02_RS02355 WP_073685669.1 475422..477296(+) (stkP/pknB) [Streptococcus salivarius strain FDAARGOS_1045]
ATGATCCAAGTTGGCAAATTATTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATTCTGGATAATGAAAAAGTGGCTATTAAGGTACTTCGTACCAATTACCAAACTGATCAGGTGG
CTGTGGCCCGTTTCCAACGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTATGTGGACGGTTCGGACTTGAAGAAATACATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTCCTTTCCGCCATGACTCTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTCACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACCAGTCTAACTCAAACGAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
TAAAGCGACTATCCAAAGTGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GCGATAGTGCAGTAACCATTGCACTCCAACATTTCCAAAAACCACTACCATCGATTTTGGCAGAGAACCGTAACGTTCCC
CAAGCTTTGGAAAATGTGGTTATTCGAGCAACAGCCAAAAAACTAGAAAATCGTTACAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGTGATGCCAAGGTAGTCTTTGATGATATGACGGATACCAAGACCT
TGCCGAAGGTTGATCCAGTTCCATCAGCAAGTCTTGAGAAAAAGGCGGTTGCTGCTGAACCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCAAGGAAAAAAACGACACCAGCTAAGAAGAAAAAGAAGAAGAACTTCTTCTCAACCTTACTCAAGGT
TTTTCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCCTATTTAGTCTTTACCAATCCTGATAATGTCCAAGTACCTA
ATGTGGTCGGTCAGGAGTTGTCCATAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTCAAAGAAGTG
GAAGATGACTCTGTCGATACGGGTAAGGTCATCAAGACCGATCCTATAGCTGGAACCACACGAAAAGAAGGATCAAGCAT
TGATGTCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAGGGTAAAAACTATAAGGATGCCATTGAGG
ACTTAACTTCGAATTATGGTGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAA
ATCCTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCTAAGATTAAGTTCCGTGTGGCAAC
TCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTAACGGTTTCAACAGCAGTTCAAACCTTGAATCGTAAGAATATCT
CAAGTAGTAGCATAGAGTACCACGACTATAATACTGGTGCTAAATTAGATAAGGATAAGATTCCTAGCAGTACGGAGGTC
CTTTATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGCAAGTTCAAA
CCTTCAGTCTAGCTCAAGTAGTACGACACATTCGTCATCAACAAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAA
CCTCGACAGAGGCTACTCACACAGAACTACAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(511-580)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(370-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.718

100

0.987
  pknB Streptococcus mutans UA159

66.974

86.859

0.582
  stkP Streptococcus pneumoniae TIGR4

52.265

91.987

0.481
  stkP Streptococcus pneumoniae D39

52.091

91.987

0.479
  stkP Streptococcus pneumoniae R6

52.091

91.987

0.479
  stkP Streptococcus pneumoniae Rx1

51.916

91.987

0.478