Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   I6H73_RS08085 Genome accession   NZ_CP066073
Coordinates   1613404..1615299 (-) Length   631 a.a.
NCBI ID   WP_004230538.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1016     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1608404..1620299
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H73_RS08060 (I6H73_08060) - 1609154..1609513 (-) 360 WP_003056775.1 S1 RNA-binding domain-containing protein -
  I6H73_RS08065 (I6H73_08065) - 1609513..1610913 (-) 1401 WP_014612502.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I6H73_RS08070 (I6H73_08070) - 1610950..1611591 (-) 642 WP_014612503.1 response regulator transcription factor -
  I6H73_RS08075 (I6H73_08075) - 1611584..1612588 (-) 1005 WP_003061197.1 sensor histidine kinase -
  I6H73_RS08080 (I6H73_08080) liaF 1612585..1613277 (-) 693 WP_015057977.1 cell wall-active antibiotics response protein LiaF -
  I6H73_RS08085 (I6H73_08085) pknB 1613404..1615299 (-) 1896 WP_004230538.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  I6H73_RS08090 (I6H73_08090) - 1615296..1616036 (-) 741 WP_003061786.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  I6H73_RS08095 (I6H73_08095) rsmB 1616074..1617396 (-) 1323 WP_003060995.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  I6H73_RS08100 (I6H73_08100) fmt 1617386..1618321 (-) 936 WP_065359323.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 631 a.a.        Molecular weight: 68711.08 Da        Isoelectric Point: 7.2906

>NTDB_id=517191 I6H73_RS08085 WP_004230538.1 1613404..1615299(-) (pknB) [Streptococcus dysgalactiae strain FDAARGOS_1016]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGADLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKNGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENHNVP
QALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYNRSRERKVIFDDVESTKPLPKVTPAPVTTPKVAPTPVTSTTESRL
EHTNQMDTLQKPQKKKRNGRFLGTLLKILFSLFIVGVALFTYLVLTKPTSVKVPNVTGVSLKVAKQELQDLGLKVGKVRQ
IESDTVAEGNVVRTDPPTGTAKRKGSAITVYLSIGNKGFEMENYKGIDYQEAMASLMETYGVPKSKIKIERIVTNEYTEN
TVISQSPSAGDKFNPNGKSKITLSVAVSDTVIMPMVTEYTYADAVNTLTALGIEASRIKAYAPSSSSATGFVQVNSPSSK
AIVSGQTPYYGTTLSLSEKGEISLYLYPEETHSSSSSTSSEASSSSSSTNDGTGTSSNTELSPSESAGQTP

Nucleotide


Download         Length: 1896 bp        

>NTDB_id=517191 I6H73_RS08085 WP_004230538.1 1613404..1615299(-) (pknB) [Streptococcus dysgalactiae strain FDAARGOS_1016]
ATGATTCAGATTGGCAAGTTATTTGCTGGTCGTTATCGCATTCTAAAATCTATTGGCCGCGGTGGTATGGCGGATGTTTA
TTTAGCAAATGATCTAATCTTGGATAATGAAGACGTTGCAATCAAGGTTTTACGTACCAATTATCAGACAGATCAGGTAG
CGGTTGCCCGTTTCCAACGGGAAGCGCGTGCCATGGCTGAGTTAAACCATCCTAATATTGTTGCCATCCGGGATATAGGT
GAAGAAGACGGACAGCAATTTTTAGTAATGGAATACGTAGATGGCGCTGACTTAAAGAAGTATATTCAAGATCATGCTCC
TCTATCCAATAATGAAGTGGTCAGAATCATGGAAGAGGTGCTTTCTGCCATGACATTAGCTCACCAGAAAGGGATTGTTC
ATAGAGATTTAAAACCTCAAAACATTCTTTTAACTAAAAATGGTGTGGTTAAGGTAACTGACTTTGGGATTGCCGTTGCT
TTTGCGGAAACGAGTTTGACTCAAACCAACTCTATGTTGGGAAGCGTCCATTACCTATCGCCTGAGCAGGCTCGCGGCTC
AAAAGCGACCATTCAAAGTGATATTTATGCGATGGGAATTATGCTCTTTGAAATGTTGACAGGACATATCCCTTATGATG
GCGATAGTGCTGTTACCATTGCTTTGCAACATTTCCAAAAGCCTCTTCCGTCTATTATTGACGAAAACCACAATGTACCG
CAAGCTTTAGAGAATGTGGTTATCCGAGCAACAGCTAAGAAATTAAGCGATCGTTACGGATCAACCTTTGAAATGAGTCG
TGATCTGATGACGGCTCTCAGTTACAACCGGAGTCGTGAACGGAAAGTTATTTTTGATGATGTGGAAAGCACAAAACCTC
TCCCTAAAGTAACACCGGCACCAGTAACGACGCCAAAAGTAGCTCCAACTCCTGTTACGTCCACAACTGAAAGTCGTTTA
GAACACACTAATCAGATGGATACGCTCCAGAAACCACAAAAAAAGAAGCGAAATGGTCGTTTCTTGGGTACTTTGTTAAA
AATCCTCTTTTCTCTTTTTATTGTAGGTGTGGCTCTCTTCACTTACTTGGTGCTAACAAAACCTACCTCAGTAAAAGTTC
CTAACGTGACAGGTGTCAGTCTTAAAGTTGCAAAGCAGGAACTGCAAGATTTAGGCTTGAAAGTTGGTAAGGTGAGACAG
ATTGAAAGTGATACTGTTGCGGAAGGGAATGTTGTCCGAACGGATCCACCAACGGGAACAGCCAAGCGCAAGGGTTCAGC
TATCACAGTTTACTTGTCAATTGGTAATAAAGGGTTTGAGATGGAAAACTACAAAGGGATTGATTATCAAGAAGCCATGG
CTAGCTTGATGGAAACTTACGGTGTTCCTAAATCGAAGATTAAGATTGAACGAATCGTGACCAATGAATACACGGAAAAT
ACTGTTATTAGCCAATCTCCGAGTGCAGGGGATAAATTTAATCCTAATGGGAAATCTAAAATTACTCTTAGTGTTGCCGT
GAGTGACACAGTCATTATGCCTATGGTAACAGAATATACCTATGCTGATGCAGTAAATACTTTGACAGCATTAGGTATTG
AAGCTTCAAGGATTAAAGCTTATGCTCCAAGCTCAAGTTCAGCAACAGGTTTTGTTCAGGTTAATTCTCCAAGTTCAAAA
GCTATTGTCAGTGGTCAAACCCCTTATTACGGTACCACATTGAGCCTCTCTGAAAAAGGTGAGATAAGCCTTTACCTTTA
CCCAGAAGAAACGCATTCTTCAAGTAGTTCAACCAGTTCTGAGGCAAGTTCTAGCAGTTCCTCAACAAATGATGGAACGG
GAACAAGTAGTAATACTGAATTAAGCCCATCGGAATCAGCTGGTCAAACCCCTTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-233)

PASTA domain (PASTA)

(511-587)

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(371-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

65.358

92.868

0.607
  stkP/pknB Streptococcus salivarius strain HSISS4

62.017

94.295

0.585
  stkP Streptococcus pneumoniae TIGR4

58.221

81.933

0.477
  stkP Streptococcus pneumoniae D39

58.027

81.933

0.475
  stkP Streptococcus pneumoniae R6

58.027

81.933

0.475
  stkP Streptococcus pneumoniae Rx1

57.834

81.933

0.474